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Items: 1 to 20 of 67

1.

Elimination of Amyloid beta Neurotoxicity.

Blanchard BJ, Hiniker AE, Lu CC, Margolin Y, Yu AS, Ingram VM.

J Alzheimers Dis. 2000 Jun;2(2):137-149.

PMID:
12214104
2.

Mechanism and prevention of neurotoxicity caused by beta-amyloid peptides: relation to Alzheimer's disease.

Blanchard BJ, Konopka G, Russell M, Ingram VM.

Brain Res. 1997 Nov 21;776(1-2):40-50.

PMID:
9439794
3.

Peptide and protein mimetics inhibiting amyloid beta-peptide aggregation.

Takahashi T, Mihara H.

Acc Chem Res. 2008 Oct;41(10):1309-18. doi: 10.1021/ar8000475.

PMID:
18937396
4.

Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils.

De Ferrari GV, Chacón MA, Barría MI, Garrido JL, Godoy JA, Olivares G, Reyes AE, Alvarez A, Bronfman M, Inestrosa NC.

Mol Psychiatry. 2003 Feb;8(2):195-208.

PMID:
12610652
5.

Role of methionine 35 in the intracellular Ca2+ homeostasis dysregulation and Ca2+-dependent apoptosis induced by amyloid beta-peptide in human neuroblastoma IMR32 cells.

Piacentini R, Ripoli C, Leone L, Misiti F, Clementi ME, D'Ascenzo M, Giardina B, Azzena GB, Grassi C.

J Neurochem. 2008 Nov;107(4):1070-82. doi: 10.1111/j.1471-4159.2008.05680.x.

6.

Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death.

Resende R, Ferreiro E, Pereira C, Resende de Oliveira C.

Neuroscience. 2008 Aug 26;155(3):725-37. doi: 10.1016/j.neuroscience.2008.06.036. Epub 2008 Jun 19.

PMID:
18621106
7.

Modulation of calcium/calmodulin kinase-II provides partial neuroprotection against beta-amyloid peptide toxicity.

Lin KF, Chang RC, Suen KC, So KF, Hugon J.

Eur J Neurosci. 2004 Apr;19(8):2047-55.

PMID:
15090032
8.

Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies.

Pereira C, Agostinho P, Moreira PI, Cardoso SM, Oliveira CR.

Curr Drug Targets CNS Neurol Disord. 2005 Aug;4(4):383-403. Review.

PMID:
16101556
9.

Protective effect of colostrinin on neuroblastoma cell survival is due to reduced aggregation of beta-amyloid.

Schuster D, Rajendran A, Hui SW, Nicotera T, Srikrishnan T, Kruzel ML.

Neuropeptides. 2005 Aug;39(4):419-26.

PMID:
15890402
10.

Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers.

Robert R, Dolezal O, Waddington L, Hattarki MK, Cappai R, Masters CL, Hudson PJ, Wark KL.

Protein Eng Des Sel. 2009 Mar;22(3):199-208. doi: 10.1093/protein/gzn052. Epub 2008 Oct 16.

PMID:
18927231
13.

A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid beta proteins in vitro and in vivo.

Fujiwara H, Tabuchi M, Yamaguchi T, Iwasaki K, Furukawa K, Sekiguchi K, Ikarashi Y, Kudo Y, Higuchi M, Saido TC, Maeda S, Takashima A, Hara M, Yaegashi N, Kase Y, Arai H.

J Neurochem. 2009 Jun;109(6):1648-57. doi: 10.1111/j.1471-4159.2009.06069.x. Epub 2009 May 7.

14.

Structure-function implications in Alzheimer's disease: effect of Abeta oligomers at central synapses.

Cerpa W, Dinamarca MC, Inestrosa NC.

Curr Alzheimer Res. 2008 Jun;5(3):233-43. Review.

PMID:
18537540
15.

Acetylcholinesterase (AChE)--amyloid-beta-peptide complexes in Alzheimer's disease. the Wnt signaling pathway.

Inestrosa NC, Urra S, Colombres M.

Curr Alzheimer Res. 2004 Nov;1(4):249-54. Review.

PMID:
15975054
16.

Alzheimer's disease pathogenesis and therapeutic interventions.

Parihar MS, Hemnani T.

J Clin Neurosci. 2004 Jun;11(5):456-67. Review.

PMID:
15177383
17.

Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers.

Demuro A, Mina E, Kayed R, Milton SC, Parker I, Glabe CG.

J Biol Chem. 2005 Apr 29;280(17):17294-300. Epub 2005 Feb 17.

18.

Glutamate and amyloid beta-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms.

Hiruma H, Katakura T, Takahashi S, Ichikawa T, Kawakami T.

J Neurosci. 2003 Oct 1;23(26):8967-77.

19.

22R-Hydroxycholesterol protects neuronal cells from beta-amyloid-induced cytotoxicity by binding to beta-amyloid peptide.

Yao ZX, Brown RC, Teper G, Greeson J, Papadopoulos V.

J Neurochem. 2002 Dec;83(5):1110-9.

20.

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity.

Ferreiro E, Resende R, Costa R, Oliveira CR, Pereira CM.

Neurobiol Dis. 2006 Sep;23(3):669-78. Epub 2006 Jul 17.

PMID:
16844381

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