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Persistence of wild-type virus and lack of temporal structure in the latent reservoir for human immunodeficiency virus type 1 in pediatric patients with extensive antiretroviral exposure.

Ruff CT, Ray SC, Kwon P, Zinn R, Pendleton A, Hutton N, Ashworth R, Gange S, Quinn TC, Siliciano RF, Persaud D.

J Virol. 2002 Sep;76(18):9481-92.


A stable latent reservoir for HIV-1 in resting CD4(+) T lymphocytes in infected children.

Persaud D, Pierson T, Ruff C, Finzi D, Chadwick KR, Margolick JB, Ruff A, Hutton N, Ray S, Siliciano RF.

J Clin Invest. 2000 Apr;105(7):995-1003.


HIV-1 drug resistance profiles in children and adults with viral load of <50 copies/ml receiving combination therapy.

Hermankova M, Ray SC, Ruff C, Powell-Davis M, Ingersoll R, D'Aquila RT, Quinn TC, Siliciano JD, Siliciano RF, Persaud D.

JAMA. 2001 Jul 11;286(2):196-207.


A novel assay allows genotyping of the latent reservoir for human immunodeficiency virus type 1 in the resting CD4+ T cells of viremic patients.

Monie D, Simmons RP, Nettles RE, Kieffer TL, Zhou Y, Zhang H, Karmon S, Ingersoll R, Chadwick K, Zhang H, Margolick JB, Quinn TC, Ray SC, Wind-Rotolo M, Miller M, Persaud D, Siliciano RF.

J Virol. 2005 Apr;79(8):5185-202.


Autologous neutralizing antibody to human immunodeficiency virus-1 and replication-competent virus recovered from CD4+ T-cell reservoirs in pediatric HIV-1-infected patients on HAART.

Ching N, Nielsen-Saines KA, Deville JG, Wei LS, Garratty E, Bryson YJ.

AIDS Res Hum Retroviruses. 2010 May;26(5):585-91. doi: 10.1089/aid.2008.0274.


Limits on replenishment of the resting CD4+ T cell reservoir for HIV in patients on HAART.

Sedaghat AR, Siliciano JD, Brennan TP, Wilke CO, Siliciano RF.

PLoS Pathog. 2007 Aug 31;3(8):e122.


Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo.

Hermankova M, Siliciano JD, Zhou Y, Monie D, Chadwick K, Margolick JB, Quinn TC, Siliciano RF.

J Virol. 2003 Jul;77(13):7383-92.


Slow human immunodeficiency virus type 1 evolution in viral reservoirs in infants treated with effective antiretroviral therapy.

Persaud D, Ray SC, Kajdas J, Ahonkhai A, Siberry GK, Ferguson K, Ziemniak C, Quinn TC, Casazza JP, Zeichner S, Gange SJ, Watson DC.

AIDS Res Hum Retroviruses. 2007 Mar;23(3):381-90.


The challenge of viral reservoirs in HIV-1 infection.

Blankson JN, Persaud D, Siliciano RF.

Annu Rev Med. 2002;53:557-93. Review.


The lymphocyte HIV reservoir in patients on long-term HAART is a memory of virus evolution.

Lambotte O, Chaix ML, Gubler B, Nasreddine N, Wallon C, Goujard C, Rouzioux C, Taoufik Y, Delfraissy JF.

AIDS. 2004 May 21;18(8):1147-58.


Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy.

Finzi D, Hermankova M, Pierson T, Carruth LM, Buck C, Chaisson RE, Quinn TC, Chadwick K, Margolick J, Brookmeyer R, Gallant J, Markowitz M, Ho DD, Richman DD, Siliciano RF.

Science. 1997 Nov 14;278(5341):1295-300.


Lack of evidence for protease evolution in HIV-1-infected patients after 2 years of successful highly active antiretroviral therapy.

Parera M, Ibañez A, Clotet B, Martinez MA.

J Infect Dis. 2004 Apr 15;189(8):1444-51. Epub 2004 Apr 5.


HIV DNA subspecies persist in both activated and resting memory CD4+ T cells during antiretroviral therapy.

Murray JM, Zaunders JJ, McBride KL, Xu Y, Bailey M, Suzuki K, Cooper DA, Emery S, Kelleher AD, Koelsch KK; PINT Study Team.

J Virol. 2014 Mar;88(6):3516-26. doi: 10.1128/JVI.03331-13. Epub 2014 Jan 8.


Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy.

Chun TW, Stuyver L, Mizell SB, Ehler LA, Mican JA, Baseler M, Lloyd AL, Nowak MA, Fauci AS.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13193-7.


Low-level HIV-1 replication and the dynamics of the resting CD4+ T cell reservoir for HIV-1 in the setting of HAART.

Sedaghat AR, Siliciano RF, Wilke CO.

BMC Infect Dis. 2008 Jan 2;8:2. doi: 10.1186/1471-2334-8-2.


Study of the impact of HIV genotypic drug resistance testing on therapy efficacy.

Van Vaerenbergh K.

Verh K Acad Geneeskd Belg. 2001;63(5):447-73. Review.


Drug-resistant variants that evolve during nonsuppressive therapy persist in HIV-1-infected peripheral blood mononuclear cells after long-term highly active antiretroviral therapy.

Verhofstede C, Noë A, Demecheleer E, De Cabooter N, Van Wanzeele F, Van Der Gucht B, Vogelaers D, Plum J.

J Acquir Immune Defic Syndr. 2004 Apr 15;35(5):473-83.


Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy.

Zhang L, Ramratnam B, Tenner-Racz K, He Y, Vesanen M, Lewin S, Talal A, Racz P, Perelson AS, Korber BT, Markowitz M, Ho DD.

N Engl J Med. 1999 May 27;340(21):1605-13.

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