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Items: 1 to 20 of 304

1.

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair.

Hopfner KP, Craig L, Moncalian G, Zinkel RA, Usui T, Owen BA, Karcher A, Henderson B, Bodmer JL, McMurray CT, Carney JP, Petrini JH, Tainer JA.

Nature. 2002 Aug 1;418(6897):562-6.

PMID:
12152085
2.

Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microscopy.

Anderson DE, Trujillo KM, Sung P, Erickson HP.

J Biol Chem. 2001 Oct 5;276(40):37027-33. Epub 2001 Jul 24.

3.

The Rad50 hook domain is a critical determinant of Mre11 complex functions.

Wiltzius JJ, Hohl M, Fleming JC, Petrini JH.

Nat Struct Mol Biol. 2005 May;12(5):403-7. Epub 2005 Apr 24.

PMID:
15852023
4.

The rad50 signature motif: essential to ATP binding and biological function.

Moncalian G, Lengsfeld B, Bhaskara V, Hopfner KP, Karcher A, Alden E, Tainer JA, Paull TT.

J Mol Biol. 2004 Jan 23;335(4):937-51.

PMID:
14698290
5.

Dimerization of the Rad50 protein is independent of the conserved hook domain.

Cahill D, Carney JP.

Mutagenesis. 2007 Jul;22(4):269-74. Epub 2007 Apr 9.

PMID:
17426050
6.
7.

Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast.

Chen L, Trujillo KM, Van Komen S, Roh DH, Krejci L, Lewis LK, Resnick MA, Sung P, Tomkinson AE.

J Biol Chem. 2005 Jan 28;280(4):2620-7. Epub 2004 Nov 16.

8.

Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.

Hopfner KP, Karcher A, Craig L, Woo TT, Carney JP, Tainer JA.

Cell. 2001 May 18;105(4):473-85.

9.

Yeast xrs2 binds DNA and helps target rad50 and mre11 to DNA ends.

Trujillo KM, Roh DH, Chen L, Van Komen S, Tomkinson A, Sung P.

J Biol Chem. 2003 Dec 5;278(49):48957-64. Epub 2003 Sep 30.

11.

The Mre11/Rad50/Xrs2 complex and non-homologous end-joining of incompatible ends in S. cerevisiae.

Zhang X, Paull TT.

DNA Repair (Amst). 2005 Nov 21;4(11):1281-94. Epub 2005 Jul 25.

PMID:
16043424
12.

Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.

Lee JH, Ghirlando R, Bhaskara V, Hoffmeyer MR, Gu J, Paull TT.

J Biol Chem. 2003 Nov 14;278(46):45171-81. Epub 2003 Sep 8.

13.

DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex.

Trujillo KM, Sung P.

J Biol Chem. 2001 Sep 21;276(38):35458-64. Epub 2001 Jul 13.

14.

Tethering on the brink: the evolutionarily conserved Mre11-Rad50 complex.

Connelly JC, Leach DR.

Trends Biochem Sci. 2002 Aug;27(8):410-8. Review.

PMID:
12151226
15.
16.

ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.

Williams GJ, Williams RS, Williams JS, Moncalian G, Arvai AS, Limbo O, Guenther G, SilDas S, Hammel M, Russell P, Tainer JA.

Nat Struct Mol Biol. 2011 Apr;18(4):423-31. doi: 10.1038/nsmb.2038. Epub 2011 Mar 27. Erratum in: Nat Struct Mol Biol. 2012 Mar;19(3):364. Nat Struct Mol Biol. 2011 Sep;18(9):1084.

17.

Crystal structure of the Mre11-Rad50-ATPγS complex: understanding the interplay between Mre11 and Rad50.

Lim HS, Kim JS, Park YB, Gwon GH, Cho Y.

Genes Dev. 2011 May 15;25(10):1091-104. doi: 10.1101/gad.2037811. Epub 2011 Apr 21.

18.
19.

Interdependence of the rad50 hook and globular domain functions.

Hohl M, Kochańczyk T, Tous C, Aguilera A, Krężel A, Petrini JH.

Mol Cell. 2015 Feb 5;57(3):479-91. doi: 10.1016/j.molcel.2014.12.018. Epub 2015 Jan 15.

20.

The plant Rad50-Mre11 protein complex.

Daoudal-Cotterell S, Gallego ME, White CI.

FEBS Lett. 2002 Apr 10;516(1-3):164-6.

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