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Items: 1 to 20 of 398

1.

ATR enforces the topoisomerase II-dependent G2 checkpoint through inhibition of Plk1 kinase.

Deming PB, Flores KG, Downes CS, Paules RS, Kaufmann WK.

J Biol Chem. 2002 Sep 27;277(39):36832-8. Epub 2002 Jul 29.

2.

The human decatenation checkpoint.

Deming PB, Cistulli CA, Zhao H, Graves PR, Piwnica-Worms H, Paules RS, Downes CS, Kaufmann WK.

Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12044-9. Epub 2001 Oct 2.

3.

Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage.

Tsvetkov L, Stern DF.

Cell Cycle. 2005 Jan;4(1):166-71. Epub 2005 Jan 5.

PMID:
15611664
4.

Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.

Bower JJ, Zhou Y, Zhou T, Simpson DA, Arlander SJ, Paules RS, Cordeiro-Stone M, Kaufmann WK.

Cell Cycle. 2010 Apr 15;9(8):1617-28. Epub 2010 Apr 15.

5.

Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase.

Toyoshima-Morimoto F, Taniguchi E, Shinya N, Iwamatsu A, Nishida E.

Nature. 2001 Mar 8;410(6825):215-20. Erratum in: Nature 2001 Apr 12;410(6830):847.

PMID:
11242082
6.

Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase.

Yim H, Erikson RL.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19742-7. doi: 10.1073/pnas.1013557107. Epub 2010 Nov 1.

7.

FGF inhibits the activity of the cyclin B1/CDK1 kinase to induce a transient G₂arrest in RCS chondrocytes.

Tran T, Kolupaeva V, Basilico C.

Cell Cycle. 2010 Nov 1;9(21):4379-86. Epub 2010 Nov 15.

8.

The auto-ubiquitylation of E3 ubiquitin-protein ligase Chfr at G2 phase is required for accumulation of polo-like kinase 1 and mitotic entry in mammalian cells.

Kim JS, Park YY, Park SY, Cho H, Kang D, Cho H.

J Biol Chem. 2011 Sep 2;286(35):30615-23. doi: 10.1074/jbc.M111.231803. Epub 2011 Jul 15.

9.

Loss of p53 induces M-phase retardation following G2 DNA damage checkpoint abrogation.

Minemoto Y, Uchida S, Ohtsubo M, Shimura M, Sasagawa T, Hirata M, Nakagama H, Ishizaka Y, Yamashita K.

Arch Biochem Biophys. 2003 Apr 1;412(1):13-9.

PMID:
12646262
10.

Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.

Lee HJ, Hwang HI, Jang YJ.

Cell Cycle. 2010 Jun 15;9(12):2389-98. Epub 2010 Jun 15.

PMID:
20581453
11.

Degradation of ATM-independent decatenation checkpoint function in human cells is secondary to inactivation of p53 and correlated with chromosomal destabilization.

Kaufmann WK, Campbell CB, Simpson DA, Deming PB, Filatov L, Galloway DA, Zhao XJ, Creighton AM, Downes CS.

Cell Cycle. 2002 May-Jun;1(3):210-9.

PMID:
12429935
12.

Polo-like kinase-1 is a target of the DNA damage checkpoint.

Smits VA, Klompmaker R, Arnaud L, Rijksen G, Nigg EA, Medema RH.

Nat Cell Biol. 2000 Sep;2(9):672-6.

PMID:
10980711
14.

Active cyclin B1-Cdk1 first appears on centrosomes in prophase.

Jackman M, Lindon C, Nigg EA, Pines J.

Nat Cell Biol. 2003 Feb;5(2):143-8.

PMID:
12524548
15.

Regulation of Polo-like kinase 1 by DNA damage in mitosis. Inhibition of mitotic PLK-1 by protein phosphatase 2A.

Jang YJ, Ji JH, Choi YC, Ryu CJ, Ko SY.

J Biol Chem. 2007 Jan 26;282(4):2473-82. Epub 2006 Nov 22.

17.

p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress.

Charrier-Savournin FB, Château MT, Gire V, Sedivy J, Piette J, Dulic V.

Mol Biol Cell. 2004 Sep;15(9):3965-76. Epub 2004 Jun 4.

18.

Cooperative phosphorylation including the activity of polo-like kinase 1 regulates the subcellular localization of cyclin B1.

Yuan J, Eckerdt F, Bereiter-Hahn J, Kurunci-Csacsko E, Kaufmann M, Strebhardt K.

Oncogene. 2002 Nov 28;21(54):8282-92.

19.

Polo-like kinase 1 inactivation following mitotic DNA damaging treatments is independent of ataxia telangiectasia mutated kinase.

Yuan JH, Feng Y, Fisher RH, Maloid S, Longo DL, Ferris DK.

Mol Cancer Res. 2004 Jul;2(7):417-26.

20.

Human topoisomerase II function, tyrosine phosphorylation and cell cycle checkpoints.

Kaufmann WK.

Proc Soc Exp Biol Med. 1998 Mar;217(3):327-34. Review.

PMID:
9492343

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