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Items: 1 to 20 of 115

1.

The phosphoinositide 3-kinase pathway.

Cantley LC.

Science. 2002 May 31;296(5573):1655-7. Review.

PMID:
12040186
2.

The role of PI 3-kinase in insulin action.

Alessi DR, Downes CP.

Biochim Biophys Acta. 1998 Dec 8;1436(1-2):151-64. Review.

PMID:
9838087
3.

The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation.

Carricaburu V, Lamia KA, Lo E, Favereaux L, Payrastre B, Cantley LC, Rameh LE.

Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9867-72. Epub 2003 Aug 1.

4.

Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction.

Corvera S, Czech MP.

Trends Cell Biol. 1998 Nov;8(11):442-6. Review.

PMID:
9854311
5.

PI3K-Akt pathway: its functions and alterations in human cancer.

Osaki M, Oshimura M, Ito H.

Apoptosis. 2004 Nov;9(6):667-76. Review.

PMID:
15505410
6.

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B.

Stephens L, Anderson K, Stokoe D, Erdjument-Bromage H, Painter GF, Holmes AB, Gaffney PR, Reese CB, McCormick F, Tempst P, Coadwell J, Hawkins PT.

Science. 1998 Jan 30;279(5351):710-4.

7.
8.

Phosphatidylinositol Phosphate 5-Kinase Iγ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth.

Thapa N, Choi S, Tan X, Wise T, Anderson RA.

J Biol Chem. 2015 Jul 24;290(30):18843-54. doi: 10.1074/jbc.M114.596742. Epub 2015 Jun 12.

9.

RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1.

Kim DW, Hwang JH, Suh JM, Kim H, Song JH, Hwang ES, Hwang IY, Park KC, Chung HK, Kim JM, Park J, Hemmings BA, Shong M.

Mol Endocrinol. 2003 Jul;17(7):1382-94. Epub 2003 May 8.

PMID:
12738763
10.

Endomembrane PtdIns(3,4,5)P3 activates the PI3K-Akt pathway.

Jethwa N, Chung GH, Lete MG, Alonso A, Byrne RD, Calleja V, Larijani B.

J Cell Sci. 2015 Sep 15;128(18):3456-65. doi: 10.1242/jcs.172775. Epub 2015 Aug 3.

11.

The PI3K-PDK1 connection: more than just a road to PKB.

Vanhaesebroeck B, Alessi DR.

Biochem J. 2000 Mar 15;346 Pt 3:561-76. Review.

12.

The phosphatidylinositol 3-Kinase AKT pathway in human cancer.

Vivanco I, Sawyers CL.

Nat Rev Cancer. 2002 Jul;2(7):489-501. Review. No abstract available.

PMID:
12094235
13.

Imaging antigen-induced PI3K activation in T cells.

Harriague J, Bismuth G.

Nat Immunol. 2002 Nov;3(11):1090-6. Epub 2002 Oct 21.

PMID:
12389041
14.

Copper ions strongly activate the phosphoinositide-3-kinase/Akt pathway independent of the generation of reactive oxygen species.

Ostrakhovitch EA, Lordnejad MR, Schliess F, Sies H, Klotz LO.

Arch Biochem Biophys. 2002 Jan 15;397(2):232-9.

PMID:
11795876
15.

Herpes simplex virus protein kinases US3 and UL13 modulate VP11/12 phosphorylation, virion packaging, and phosphatidylinositol 3-kinase/Akt signaling activity.

Eaton HE, Saffran HA, Wu FW, Quach K, Smiley JR.

J Virol. 2014 Jul;88(13):7379-88. doi: 10.1128/JVI.00712-14. Epub 2014 Apr 16.

17.

Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase.

Didichenko SA, Tilton B, Hemmings BA, Ballmer-Hofer K, Thelen M.

Curr Biol. 1996 Oct 1;6(10):1271-8.

18.

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B.

Stokoe D, Stephens LR, Copeland T, Gaffney PR, Reese CB, Painter GF, Holmes AB, McCormick F, Hawkins PT.

Science. 1997 Jul 25;277(5325):567-70.

19.

Association of PI3K-Akt signaling pathway with digitalis-induced hypertrophy of cardiac myocytes.

Liu L, Zhao X, Pierre SV, Askari A.

Am J Physiol Cell Physiol. 2007 Nov;293(5):C1489-97. Epub 2007 Aug 29.

20.

A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.

Sekulić A, Hudson CC, Homme JL, Yin P, Otterness DM, Karnitz LM, Abraham RT.

Cancer Res. 2000 Jul 1;60(13):3504-13.

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