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Items: 1 to 20 of 98

1.

Distinct Mg(2+)-dependent steps rate limit opening and closing of a single CFTR Cl(-) channel.

Dousmanis AG, Nairn AC, Gadsby DC.

J Gen Physiol. 2002 Jun;119(6):545-59.

2.

ATP hydrolysis cycles and the gating of CFTR Cl- channels.

Gadsby DC, Dousmanis AG, Nairn AC.

Acta Physiol Scand Suppl. 1998 Aug;643:247-56. Review.

PMID:
9789567
3.

Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis.

Hwang TC, Nagel G, Nairn AC, Gadsby DC.

Proc Natl Acad Sci U S A. 1994 May 24;91(11):4698-702.

4.

Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains.

Csanády L, Chan KW, Seto-Young D, Kopsco DC, Nairn AC, Gadsby DC.

J Gen Physiol. 2000 Sep;116(3):477-500.

5.

Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle.

Baukrowitz T, Hwang TC, Nairn AC, Gadsby DC.

Neuron. 1994 Mar;12(3):473-82.

PMID:
7512348
6.

Regulation of CFTR Cl- channel gating by ATP binding and hydrolysis.

Ikuma M, Welsh MJ.

Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8675-80.

7.

Thermodynamics of CFTR channel gating: a spreading conformational change initiates an irreversible gating cycle.

Csanády L, Nairn AC, Gadsby DC.

J Gen Physiol. 2006 Nov;128(5):523-33. Epub 2006 Oct 16.

9.

Cysteine accessibility probes timing and extent of NBD separation along the dimer interface in gating CFTR channels.

Chaves LA, Gadsby DC.

J Gen Physiol. 2015 Apr;145(4):261-83. doi: 10.1085/jgp.201411347.

10.
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13.

State-dependent modulation of CFTR gating by pyrophosphate.

Tsai MF, Shimizu H, Sohma Y, Li M, Hwang TC.

J Gen Physiol. 2009 Apr;133(4):405-19. doi: 10.1085/jgp.200810186.

14.

The non-hydrolytic pathway of cystic fibrosis transmembrane conductance regulator ion channel gating.

Aleksandrov AA, Chang X, Aleksandrov L, Riordan JR.

J Physiol. 2000 Oct 15;528 Pt 2:259-65.

15.
16.

The CFTR chloride channel: nucleotide interactions and temperature-dependent gating.

Mathews CJ, Tabcharani JA, Hanrahan JW.

J Membr Biol. 1998 May 1;163(1):55-66.

PMID:
9569250
17.

CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains.

Vergani P, Lockless SW, Nairn AC, Gadsby DC.

Nature. 2005 Feb 24;433(7028):876-80.

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19.

G551D and G1349D, two CF-associated mutations in the signature sequences of CFTR, exhibit distinct gating defects.

Bompadre SG, Sohma Y, Li M, Hwang TC.

J Gen Physiol. 2007 Apr;129(4):285-98. Epub 2007 Mar 12.

20.

On the mechanism of MgATP-dependent gating of CFTR Cl- channels.

Vergani P, Nairn AC, Gadsby DC.

J Gen Physiol. 2003 Jan;121(1):17-36.

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