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Items: 1 to 20 of 143


The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins.

Henis-Korenblit S, Shani G, Sines T, Marash L, Shohat G, Kimchi A.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5400-5. Epub 2002 Apr 9.


Expression of fragments of translation initiation factor eIF4GI reveals a nuclear localisation signal within the N-terminal apoptotic cleavage fragment N-FAG.

Coldwell MJ, Hashemzadeh-Bonehi L, Hinton TM, Morley SJ, Pain VM.

J Cell Sci. 2004 May 15;117(Pt 12):2545-55. Epub 2004 May 5.


DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis.

Marash L, Liberman N, Henis-Korenblit S, Sivan G, Reem E, Elroy-Stein O, Kimchi A.

Mol Cell. 2008 May 23;30(4):447-59. doi: 10.1016/j.molcel.2008.03.018. Epub 2008 May 1.


Translation driven by an eIF4G core domain in vivo.

De Gregorio E, Preiss T, Hentze MW.

EMBO J. 1999 Sep 1;18(17):4865-74.


The eIF4G homolog DAP5/p97 supports the translation of select mRNAs during endoplasmic reticulum stress.

Lewis SM, Cerquozzi S, Graber TE, Ungureanu NH, Andrews M, Holcik M.

Nucleic Acids Res. 2008 Jan;36(1):168-78. Epub 2007 Nov 14.


The crystal structure of the C-terminal DAP5/p97 domain sheds light on the molecular basis for its processing by caspase cleavage.

Liberman N, Dym O, Unger T, Albeck S, Peleg Y, Jacobovitch Y, Branzburg A, Eisenstein M, Marash L, Kimchi A.

J Mol Biol. 2008 Nov 14;383(3):539-48. doi: 10.1016/j.jmb.2008.08.013. Epub 2008 Aug 12.


Polypyrimidine tract-binding proteins are cleaved by caspase-3 during apoptosis.

Back SH, Shin S, Jang SK.

J Biol Chem. 2002 Jul 26;277(30):27200-9. Epub 2002 May 9.


Cleavage of eukaryotic translation initiation factor 4GII correlates with translation inhibition during apoptosis.

Marissen WE, Gradi A, Sonenberg N, Lloyd RE.

Cell Death Differ. 2000 Dec;7(12):1234-43.


The eIF4G-homolog p97 can activate translation independent of caspase cleavage.

Nousch M, Reed V, Bryson-Richardson RJ, Currie PD, Preiss T.

RNA. 2007 Mar;13(3):374-84. Epub 2007 Jan 19.


In vitro cleavage of eIF4GI but not eIF4GII by HIV-1 protease and its effects on translation in the rabbit reticulocyte lysate system.

Ohlmann T, Prévôt D, Décimo D, Roux F, Garin J, Morley SJ, Darlix JL.

J Mol Biol. 2002 Apr 19;318(1):9-20.


Cleavage of DAP5 by coxsackievirus B3 2A protease facilitates viral replication and enhances apoptosis by altering translation of IRES-containing genes.

Hanson PJ, Ye X, Qiu Y, Zhang HM, Hemida MG, Wang F, Lim T, Gu A, Cho B, Kim H, Fung G, Granville DJ, Yang D.

Cell Death Differ. 2016 May;23(5):828-40. doi: 10.1038/cdd.2015.145. Epub 2015 Nov 20.


Protection of cap-dependent protein synthesis in vivo and in vitro with an eIF4G-1 variant highly resistant to cleavage by Coxsackievirus 2A protease.

Zhao X, Lamphear BJ, Xiong D, Knowlton K, Rhoads RE.

J Biol Chem. 2003 Feb 14;278(7):4449-57. Epub 2002 Dec 9.

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