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Items: 1 to 20 of 130

1.

Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency.

Li S, Sonenberg N, Gingras AC, Peterson M, Avdulov S, Polunovsky VA, Bitterman PB.

Mol Cell Biol. 2002 Apr;22(8):2853-61.

4.

Translational repression by human 4E-BP1 in yeast specifically requires human eIF4E as target.

Hughes JM, Ptushkina M, Karim MM, Koloteva N, von der Haar T, McCarthy JE.

J Biol Chem. 1999 Feb 5;274(6):3261-4.

5.

Translational control of the antiapoptotic function of Ras.

Polunovsky VA, Gingras AC, Sonenberg N, Peterson M, Tan A, Rubins JB, Manivel JC, Bitterman PB.

J Biol Chem. 2000 Aug 11;275(32):24776-80.

6.
7.

RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation.

Villalonga P, Fernández de Mattos S, Ridley AJ.

J Biol Chem. 2009 Dec 18;284(51):35287-96. doi: 10.1074/jbc.M109.050120.

8.

Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma.

Jacobson BA, De A, Kratzke MG, Patel MR, Jay-Dixon J, Whitson BA, Sadiq AA, Bitterman PB, Polunovsky VA, Kratzke RA.

Br J Cancer. 2009 Aug 4;101(3):424-31. doi: 10.1038/sj.bjc.6605184. Epub 2009 Jul 14.

9.
10.

New hierarchical phosphorylation pathway of the translational repressor eIF4E-binding protein 1 (4E-BP1) in ischemia-reperfusion stress.

Ayuso MI, Hernández-Jiménez M, Martín ME, Salinas M, Alcázar A.

J Biol Chem. 2010 Nov 5;285(45):34355-63. doi: 10.1074/jbc.M110.135103. Epub 2010 Aug 24.

11.

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism.

Gingras AC, Gygi SP, Raught B, Polakiewicz RD, Abraham RT, Hoekstra MF, Aebersold R, Sonenberg N.

Genes Dev. 1999 Jun 1;13(11):1422-37.

12.
13.

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation.

Beretta L, Gingras AC, Svitkin YV, Hall MN, Sonenberg N.

EMBO J. 1996 Feb 1;15(3):658-64.

14.

Phosphorylation dynamics of eukaryotic initiation factor 4E binding protein 1 (4E-BP1) is discordant with its potential to interact with eukaryotic initiation factor 4E (eIF4E).

Showkat M, Beigh MA, Bhat BB, Batool A, Andrabi KI.

Cell Signal. 2014 Oct;26(10):2117-21. doi: 10.1016/j.cellsig.2014.06.008. Epub 2014 Jun 26.

PMID:
24975846
15.
16.

Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation.

Kumar V, Pandey P, Sabatini D, Kumar M, Majumder PK, Bharti A, Carmichael G, Kufe D, Kharbanda S.

EMBO J. 2000 Mar 1;19(5):1087-97.

17.
18.

Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.

Sekiyama N, Arthanari H, Papadopoulos E, Rodriguez-Mias RA, Wagner G, Léger-Abraham M.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4036-45. doi: 10.1073/pnas.1512118112. Epub 2015 Jul 13.

19.

Hierarchical phosphorylation of the translation inhibitor 4E-BP1.

Gingras AC, Raught B, Gygi SP, Niedzwiecka A, Miron M, Burley SK, Polakiewicz RD, Wyslouch-Cieszynska A, Aebersold R, Sonenberg N.

Genes Dev. 2001 Nov 1;15(21):2852-64.

20.

Protein phosphatase PPM1G regulates protein translation and cell growth by dephosphorylating 4E binding protein 1 (4E-BP1).

Liu J, Stevens PD, Eshleman NE, Gao T.

J Biol Chem. 2013 Aug 9;288(32):23225-33. doi: 10.1074/jbc.M113.492371. Epub 2013 Jun 28.

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