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Items: 1 to 20 of 187


Anthrax spores make an essential contribution to vaccine efficacy.

Brossier F, Levy M, Mock M.

Infect Immun. 2002 Feb;70(2):661-4.


Efficacy of a vaccine based on protective antigen and killed spores against experimental inhalational anthrax.

Gauthier YP, Tournier JN, Paucod JC, Corre JP, Mock M, Goossens PL, Vidal DR.

Infect Immun. 2009 Mar;77(3):1197-207. doi: 10.1128/IAI.01217-08. Epub 2008 Dec 29.


The role of antibodies to Bacillus anthracis and anthrax toxin components in inhibiting the early stages of infection by anthrax spores.

Welkos S, Little S, Friedlander A, Fritz D, Fellows P.

Microbiology. 2001 Jun;147(Pt 6):1677-85.


A novel live attenuated anthrax spore vaccine based on an acapsular Bacillus anthracis Sterne strain with mutations in the htrA, lef and cya genes.

Chitlaru T, Israeli M, Rotem S, Elia U, Bar-Haim E, Ehrlich S, Cohen O, Shafferman A.

Vaccine. 2017 Oct 20;35(44):6030-6040. doi: 10.1016/j.vaccine.2017.03.033. Epub 2017 Mar 23.


Mucosal immunization with a novel nanoemulsion-based recombinant anthrax protective antigen vaccine protects against Bacillus anthracis spore challenge.

Bielinska AU, Janczak KW, Landers JJ, Makidon P, Sower LE, Peterson JW, Baker JR Jr.

Infect Immun. 2007 Aug;75(8):4020-9. Epub 2007 May 14.


Comparative analysis of the immunologic response induced by the Sterne 34F2 live spore Bacillus anthracis vaccine in a ruminant model.

Ndumnego OC, Köhler SM, Crafford J, van Heerden H, Beyer W.

Vet Immunol Immunopathol. 2016 Oct 1;178:14-21. doi: 10.1016/j.vetimm.2016.06.005. Epub 2016 Jun 16.


Protection of farm goats by combinations of recombinant peptides and formalin inactivated spores from a lethal Bacillus anthracis challenge under field conditions.

Koehler SM, Buyuk F, Celebi O, Demiraslan H, Doganay M, Sahin M, Moehring J, Ndumnego OC, Otlu S, van Heerden H, Beyer W.

BMC Vet Res. 2017 Jul 12;13(1):220. doi: 10.1186/s12917-017-1140-2.


Immunization of mice with formalin-inactivated spores from avirulent Bacillus cereus strains provides significant protection from challenge with Bacillus anthracis Ames.

Vergis JM, Cote CK, Bozue J, Alem F, Ventura CL, Welkos SL, O'Brien AD.

Clin Vaccine Immunol. 2013 Jan;20(1):56-65. doi: 10.1128/CVI.00550-12. Epub 2012 Oct 31.


Killed but metabolically active Bacillus anthracis vaccines induce broad and protective immunity against anthrax.

Skoble J, Beaber JW, Gao Y, Lovchik JA, Sower LE, Liu W, Luckett W, Peterson JW, Calendar R, Portnoy DA, Lyons CR, Dubensky TW Jr.

Infect Immun. 2009 Apr;77(4):1649-63. doi: 10.1128/IAI.00530-08. Epub 2009 Jan 21.


Poly-gamma-d-glutamic acid and protective antigen conjugate vaccines induce functional antibodies against the protective antigen and capsule of Bacillus anthracis in guinea-pigs and rabbits.

Lee DY, Chun JH, Ha HJ, Park J, Kim BS, Oh HB, Rhie GE.

FEMS Immunol Med Microbiol. 2009 Nov;57(2):165-72. doi: 10.1111/j.1574-695X.2009.00595.x. Epub 2009 Aug 6.


Efficacious, nontoxigenic Bacillus anthracis spore vaccines based on strains expressing mutant variants of lethal toxin components.

Mendelson I, Gat O, Aloni-Grinstein R, Altboum Z, Inbar I, Kronman C, Bar-Haim E, Cohen S, Velan B, Shafferman A.

Vaccine. 2005 Dec 1;23(48-49):5688-97. Epub 2005 Feb 5.


Recombinant GroEL enhances protective antigen-mediated protection against Bacillus anthracis spore challenge.

Sinha K, Bhatnagar R.

Med Microbiol Immunol. 2013 Apr;202(2):153-65. doi: 10.1007/s00430-012-0280-z. Epub 2012 Dec 21.


Progress and novel strategies in vaccine development and treatment of anthrax.

Chitlaru T, Altboum Z, Reuveny S, Shafferman A.

Immunol Rev. 2011 Jan;239(1):221-36. doi: 10.1111/j.1600-065X.2010.00969.x. Review.


The detection of protective antigen (PA) associated with spores of Bacillus anthracis and the effects of anti-PA antibodies on spore germination and macrophage interactions.

Cote CK, Rossi CA, Kang AS, Morrow PR, Lee JS, Welkos SL.

Microb Pathog. 2005 May-Jun;38(5-6):209-25. Epub 2005 Apr 22.


An intranasal vaccine targeting both the Bacillus anthracis toxin and bacterium provides protection against aerosol spore challenge in rabbits.

Wimer-Mackin S, Hinchcliffe M, Petrie CR, Warwood SJ, Tino WT, Williams MS, Stenz JP, Cheff A, Richardson C.

Vaccine. 2006 May 1;24(18):3953-63. Epub 2006 Feb 28.


Recombinant Bacillus anthracis spore proteins enhance protection of mice primed with suboptimal amounts of protective antigen.

Cybulski RJ Jr, Sanz P, McDaniel D, Darnell S, Bull RL, O'Brien AD.

Vaccine. 2008 Sep 8;26(38):4927-39. doi: 10.1016/j.vaccine.2008.07.015. Epub 2008 Jul 25.


Revisiting the Concept of Targeting Only Bacillus anthracis Toxins as a Treatment for Anthrax.

Glinert I, Bar-David E, Sittner A, Weiss S, Schlomovitz J, Ben-Shmuel A, Mechaly A, Altboum Z, Kobiler D, Levy H.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):4878-85. doi: 10.1128/AAC.00546-16. Print 2016 Aug.


Efficiency of protection of guinea pigs against infection with Bacillus anthracis spores by passive immunization.

Kobiler D, Gozes Y, Rosenberg H, Marcus D, Reuveny S, Altboum Z.

Infect Immun. 2002 Feb;70(2):544-60.


Next-Generation Bacillus anthracis Live Attenuated Spore Vaccine Based on the htrA(-) (High Temperature Requirement A) Sterne Strain.

Chitlaru T, Israeli M, Bar-Haim E, Elia U, Rotem S, Ehrlich S, Cohen O, Shafferman A.

Sci Rep. 2016 Jan 6;6:18908. doi: 10.1038/srep18908.

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