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Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease.

Brown BG, Zhao XQ, Chait A, Fisher LD, Cheung MC, Morse JS, Dowdy AA, Marino EK, Bolson EL, Alaupovic P, Frohlich J, Albers JJ.

N Engl J Med. 2001 Nov 29;345(22):1583-92.


Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL.

Cheung MC, Zhao XQ, Chait A, Albers JJ, Brown BG.

Arterioscler Thromb Vasc Biol. 2001 Aug;21(8):1320-6.


Antioxidant versus lipid-altering therapy--some answers, more questions.

Freedman JE.

N Engl J Med. 2001 Nov 29;345(22):1636-7. No abstract available.


Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B.

Brown G, Albers JJ, Fisher LD, Schaefer SM, Lin JT, Kaplan C, Zhao XQ, Bisson BD, Fitzpatrick VF, Dodge HT.

N Engl J Med. 1990 Nov 8;323(19):1289-98.


Long-term safety and efficacy of triple combination ezetimibe/simvastatin plus extended-release niacin in patients with hyperlipidemia.

Fazio S, Guyton JR, Polis AB, Adewale AJ, Tomassini JE, Ryan NW, Tershakovec AM.

Am J Cardiol. 2010 Feb 15;105(4):487-94. doi: 10.1016/j.amjcard.2009.10.001. Epub 2009 Nov 13.


Safety and tolerability of simvastatin plus niacin in patients with coronary artery disease and low high-density lipoprotein cholesterol (The HDL Atherosclerosis Treatment Study).

Zhao XQ, Morse JS, Dowdy AA, Heise N, DeAngelis D, Frohlich J, Chait A, Albers JJ, Brown BG.

Am J Cardiol. 2004 Feb 1;93(3):307-12.


Lipid altering or antioxidant vitamins for patients with coronary disease and very low HDL cholesterol? The HDL-Atherosclerosis Treatment Study Design.

Brown BG, Zhao XQ, Chait A, Frohlich J, Cheung M, Heise N, Dowdy A, DeAngelis D, Fisher LD, Albers J.

Can J Cardiol. 1998 Apr;14 Suppl A:6A-13A. Review.


Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group.

Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, Faas FH, Linares E, Schaefer EJ, Schectman G, Wilt TJ, Wittes J.

N Engl J Med. 1999 Aug 5;341(6):410-8.


The effects of simvastatin-niacin and antioxidant therapy on HDL.

Drown DJ.

Prog Cardiovasc Nurs. 2002 Spring;17(2):102-3. No abstract available.


Lipid-altering efficacy and safety of ezetimibe/simvastatin coadministered with extended-release niacin in patients with type IIa or type IIb hyperlipidemia.

Guyton JR, Brown BG, Fazio S, Polis A, Tomassini JE, Tershakovec AM.

J Am Coll Cardiol. 2008 Apr 22;51(16):1564-72. doi: 10.1016/j.jacc.2008.03.003.


Impact of simvastatin, niacin, and/or antioxidants on cholesterol metabolism in CAD patients with low HDL.

Matthan NR, Giovanni A, Schaefer EJ, Brown BG, Lichtenstein AH.

J Lipid Res. 2003 Apr;44(4):800-6. Epub 2003 Feb 1.


[The effects of simvastatin combined with different antioxidant vitamin regimens on serum lipid profile in patients with low HDL cholesterol levels].

Pirat B, Korkmaz ME, Eroğlu S, Tayfun E, Yildirir A, Uluçam M, Ozin B, Müderrisoğlu H.

Anadolu Kardiyol Derg. 2004 Dec;4(4):318-22. Turkish.


A pilot study with simvastatin and folic acid/vitamin B12 in preparation for the Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH).

MacMahon M, Kirkpatrick C, Cummings CE, Clayton A, Robinson PJ, Tomiak RH, Liu M, Kush D, Tobert J.

Nutr Metab Cardiovasc Dis. 2000 Aug;10(4):195-203. Erratum in: Nutr Metab Cardiovasc Dis 2001 Aug;11(4):III.


Antioxidant vitamins and lipid therapy: end of a long romance?

Brown BG, Cheung MC, Lee AC, Zhao XQ, Chait A.

Arterioscler Thromb Vasc Biol. 2002 Oct 1;22(10):1535-46. Review.


Efficacy and safety of combination of extended release niacin and atorvastatin in patients with low levels of high density lipoprotein cholesterol.

Harikrishnan S, Rajeev E, Tharakan JA, Titus T, Ajit Kumar VK, Sivasankaran S, Krishnamoorthy KM, Nair K.

Indian Heart J. 2008 May-Jun;60(3):215-22.


Effects of simvastatin on the lipid profile and attainment of low-density lipoprotein cholesterol goals when added to thiazolidinedione therapy in patients with type 2 diabetes mellitus: A multicenter, randomized, double-blind, placebo-controlled trial.

Lewin AJ, Kipnes MS, Meneghini LF, Plotkin DJ, Perevozskaya IT, Shah S, Maccubbin DL, Mitchel YB, Tobert JA; Simvastatin/Thiazolidinedione Study Group.

Clin Ther. 2004 Mar;26(3):379-89.


Antioxidant nutrient supplementation and brachial reactivity in patients with coronary artery disease.

McKechnie R, Rubenfire M, Mosca L.

J Lab Clin Med. 2002 Mar;139(3):133-9.


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