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Items: 1 to 20 of 109

1.
2.

Receptor endocytosis counteracts the development of opioid tolerance.

Koch T, Widera A, Bartzsch K, Schulz S, Brandenburg LO, Wundrack N, Beyer A, Grecksch G, Höllt V.

Mol Pharmacol. 2005 Jan;67(1):280-7. Epub 2004 Oct 8.

3.

An opiate cocktail that reduces morphine tolerance and dependence.

He L, Whistler JL.

Curr Biol. 2005 Jun 7;15(11):1028-33.

4.

Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization.

He L, Fong J, von Zastrow M, Whistler JL.

Cell. 2002 Jan 25;108(2):271-82.

5.

The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence.

Martini L, Whistler JL.

Curr Opin Neurobiol. 2007 Oct;17(5):556-64. Epub 2007 Dec 18. Review.

PMID:
18068348
6.

RGS14 prevents morphine from internalizing Mu-opioid receptors in periaqueductal gray neurons.

Rodríguez-Muñoz M, de la Torre-Madrid E, Gaitán G, Sánchez-Blázquez P, Garzón J.

Cell Signal. 2007 Dec;19(12):2558-71. Epub 2007 Aug 15.

PMID:
17825524
7.

Functional characterization of human variants of the mu-opioid receptor gene.

Ravindranathan A, Joslyn G, Robertson M, Schuckit MA, Whistler JL, White RL.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10811-6. doi: 10.1073/pnas.0904509106. Epub 2009 Jun 15.

8.

Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons.

Haberstock-Debic H, Wein M, Barrot M, Colago EE, Rahman Z, Neve RL, Pickel VM, Nestler EJ, von Zastrow M, Svingos AL.

J Neurosci. 2003 May 15;23(10):4324-32.

9.

Chronic methadone treatment shows a better cost/benefit ratio than chronic morphine in mice.

Enquist J, Ferwerda M, Milan-Lobo L, Whistler JL.

J Pharmacol Exp Ther. 2012 Feb;340(2):386-92. doi: 10.1124/jpet.111.187583. Epub 2011 Nov 7.

10.

A RAVE about opioid withdrawal.

Alvarez V, Arttamangkul S, Williams JT.

Neuron. 2001 Dec 6;32(5):761-3. Review.

11.

Enhancement of morphine analgesic effect with induction of mu-opioid receptor endocytosis in rats.

Hashimoto T, Saito Y, Yamada K, Hara N, Kirihara Y, Tsuchiya M.

Anesthesiology. 2006 Sep;105(3):574-80.

PMID:
16931992
12.
13.

Morphine induces endocytosis of neuronal mu-opioid receptors through the sustained transfer of Galpha subunits to RGSZ2 proteins.

Rodríguez-Muñoz M, de la Torre-Madrid E, Sánchez-Blázquez P, Garzón J.

Mol Pain. 2007 Jul 17;3:19.

14.

Chronic ethanol consumption in rats produces opioid antinociceptive tolerance through inhibition of mu opioid receptor endocytosis.

He L, Whistler JL.

PLoS One. 2011;6(5):e19372. doi: 10.1371/journal.pone.0019372. Epub 2011 May 13.

15.

Role of receptor internalization in opioid tolerance and dependence.

Koch T, Höllt V.

Pharmacol Ther. 2008 Feb;117(2):199-206. Epub 2007 Nov 17. Review.

PMID:
18076994
17.

Opioids: cellular mechanisms of tolerance and physical dependence.

Bailey CP, Connor M.

Curr Opin Pharmacol. 2005 Feb;5(1):60-8. Review.

PMID:
15661627
18.

Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons.

Yu YJ, Arttamangkul S, Evans CJ, Williams JT, von Zastrow M.

J Neurosci. 2009 Jan 7;29(1):222-33. doi: 10.1523/JNEUROSCI.4315-08.2009.

19.

How important is protein kinase C in mu-opioid receptor desensitization and morphine tolerance?

Bailey CP, Smith FL, Kelly E, Dewey WL, Henderson G.

Trends Pharmacol Sci. 2006 Nov;27(11):558-65. Epub 2006 Sep 25.

PMID:
17000011
20.

Opioid agonists have different efficacy profiles for G protein activation, rapid desensitization, and endocytosis of mu-opioid receptors.

Borgland SL, Connor M, Osborne PB, Furness JB, Christie MJ.

J Biol Chem. 2003 May 23;278(21):18776-84. Epub 2003 Mar 17.

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