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Items: 1 to 20 of 148

1.

l-Threonine aldolase, serine hydroxymethyltransferase and fungal alanine racemase. A subgroup of strictly related enzymes specialized for different functions.

Contestabile R, Paiardini A, Pascarella S, di Salvo ML, D'Aguanno S, Bossa F.

Eur J Biochem. 2001 Dec;268(24):6508-25.

2.

Threonine aldolase and alanine racemase: novel examples of convergent evolution in the superfamily of vitamin B6-dependent enzymes.

Paiardini A, Contestabile R, D'Aguanno S, Pascarella S, Bossa F.

Biochim Biophys Acta. 2003 Apr 11;1647(1-2):214-9. Review.

PMID:
12686135
3.

Alanine racemase from Tolypocladium inflatum: a key PLP-dependent enzyme in cyclosporin biosynthesis and a model of catalytic promiscuity.

di Salvo ML, Florio R, Paiardini A, Vivoli M, D'Aguanno S, Contestabile R.

Arch Biochem Biophys. 2013 Jan 15;529(2):55-65. doi: 10.1016/j.abb.2012.11.011.

PMID:
23219598
4.

Crystal structure at 2.4 A resolution of E. coli serine hydroxymethyltransferase in complex with glycine substrate and 5-formyl tetrahydrofolate.

Scarsdale JN, Radaev S, Kazanina G, Schirch V, Wright HT.

J Mol Biol. 2000 Feb 11;296(1):155-68.

PMID:
10656824
5.

On the catalytic mechanism and stereospecificity of Escherichia coli L-threonine aldolase.

di Salvo ML, Remesh SG, Vivoli M, Ghatge MS, Paiardini A, D'Aguanno S, Safo MK, Contestabile R.

FEBS J. 2014 Jan;281(1):129-45. doi: 10.1111/febs.12581.

6.

Serine hydroxymethyltransferase and threonine aldolase: are they identical?

Ogawa H, Gomi T, Fujioka M.

Int J Biochem Cell Biol. 2000 Mar;32(3):289-301. Review.

PMID:
10716626
7.

Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation.

Seebeck FP, Hilvert D.

J Am Chem Soc. 2003 Aug 27;125(34):10158-9.

PMID:
12926923
8.

Conformational transitions driven by pyridoxal-5'-phosphate uptake in the psychrophilic serine hydroxymethyltransferase from Psychromonas ingrahamii.

Angelaccio S, Dworkowski F, Di Bello A, Milano T, Capitani G, Pascarella S.

Proteins. 2014 Oct;82(10):2831-41. doi: 10.1002/prot.24646.

PMID:
25044250
10.

Serine hydroxymethyltransferase from Plasmodium vivax is different in substrate specificity from its homologues.

Sopitthummakhun K, Maenpuen S, Yuthavong Y, Leartsakulpanich U, Chaiyen P.

FEBS J. 2009 Aug;276(15):4023-36. doi: 10.1111/j.1742-4658.2009.07111.x.

11.

Purification and properties of serine hydroxymethyltransferase from Sulfolobus solfataricus.

Delle Fratte S, White RH, Maras B, Bossa F, Schirch V.

J Bacteriol. 1997 Dec;179(23):7456-61.

12.

Serine hydroxymethyltransferase: a model enzyme for mechanistic, structural, and evolutionary studies.

Florio R, di Salvo ML, Vivoli M, Contestabile R.

Biochim Biophys Acta. 2011 Nov;1814(11):1489-96. doi: 10.1016/j.bbapap.2010.10.010. Review.

PMID:
21059411
13.

Importance of tyrosine residues of Bacillus stearothermophilus serine hydroxymethyltransferase in cofactor binding and L-allo-Thr cleavage.

Bhavani BS, Rajaram V, Bisht S, Kaul P, Prakash V, Murthy MR, Appaji Rao N, Savithri HS.

FEBS J. 2008 Sep;275(18):4606-19. doi: 10.1111/j.1742-4658.2008.06603.x.

14.

Disruption of distal interactions of Arg 262 and of substrate binding to Ser 52 affect catalysis of sheep liver cytosolic serine hydroxymethyltransferase.

Jala VR, Ambili M, Prakash V, Rao NA, Savithri HS.

Indian J Biochem Biophys. 2003 Aug;40(4):226-37.

PMID:
22900314
15.

Role of Lys-226 in the catalytic mechanism of Bacillus stearothermophilus serine hydroxymethyltransferase--crystal structure and kinetic studies.

Bhavani S, Trivedi V, Jala VR, Subramanya HS, Kaul P, Prakash V, Appaji Rao N, Savithri HS.

Biochemistry. 2005 May 10;44(18):6929-37.

PMID:
15865438
16.

Purification and partial characterization of three isoforms of serine hydroxymethyltransferase from Crithidia fasciculata.

Capelluto DG, Hellman U, Cazzulo JJ, Cannata JJ.

Mol Biochem Parasitol. 1999 Jan 25;98(2):187-201.

PMID:
10080388
17.

Catalytic and thermodynamic properties of tetrahydromethanopterin-dependent serine hydroxymethyltransferase from Methanococcus jannaschii.

Angelaccio S, Chiaraluce R, Consalvi V, Buchenau B, Giangiacomo L, Bossa F, Contestabile R.

J Biol Chem. 2003 Oct 24;278(43):41789-97.

18.
19.

Similarity between serine hydroxymethyltransferase and other pyridoxal phosphate-dependent enzymes.

Pascarella S, Schirch V, Bossa F.

FEBS Lett. 1993 Sep 27;331(1-2):145-9.

20.

Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism.

Szebenyi DM, Musayev FN, di Salvo ML, Safo MK, Schirch V.

Biochemistry. 2004 Jun 8;43(22):6865-76.

PMID:
15170323
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