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SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.

Kato H, Tjernberg A, Zhang W, Krutchinsky AN, An W, Takeuchi T, Ohtsuki Y, Sugano S, de Bruijn DR, Chait BT, Roeder RG.

J Biol Chem. 2002 Feb 15;277(7):5498-505. Epub 2001 Dec 4. Erratum in: J Biol Chem 2002 Apr 19;277(16):14350.


Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus.

Thaete C, Brett D, Monaghan P, Whitehouse S, Rennie G, Rayner E, Cooper CS, Goodwin G.

Hum Mol Genet. 1999 Apr;8(4):585-91.


Delineation of the protein domains responsible for SYT, SSX, and SYT-SSX nuclear localization.

dos Santos NR, de Bruijn DR, Kater-Baats E, Otte AP, van Kessel AG.

Exp Cell Res. 2000 Apr 10;256(1):192-202.


Transcriptional co-activator activity of SYT is negatively regulated by BRM and Brg1.

Ishida M, Tanaka S, Ohki M, Ohta T.

Genes Cells. 2004 May;9(5):419-28.


The proto-oncoprotein SYT interacts with SYT-interacting protein/co-activator activator (SIP/CoAA), a human nuclear receptor co-activator with similarity to EWS and TLS/FUS family of proteins.

Perani M, Antonson P, Hamoudi R, Ingram CJ, Cooper CS, Garrett MD, Goodwin GH.

J Biol Chem. 2005 Dec 30;280(52):42863-76. Epub 2005 Oct 14.


The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies.

Brett D, Whitehouse S, Antonson P, Shipley J, Cooper C, Goodwin G.

Hum Mol Genet. 1997 Sep;6(9):1559-64.


Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.

Nie Z, Yan Z, Chen EH, Sechi S, Ling C, Zhou S, Xue Y, Yang D, Murray D, Kanakubo E, Cleary ML, Wang W.

Mol Cell Biol. 2003 Apr;23(8):2942-52.


A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex.

Nie Z, Xue Y, Yang D, Zhou S, Deroo BJ, Archer TK, Wang W.

Mol Cell Biol. 2000 Dec;20(23):8879-88.


Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.

Crew AJ, Clark J, Fisher C, Gill S, Grimer R, Chand A, Shipley J, Gusterson BA, Cooper CS.

EMBO J. 1995 May 15;14(10):2333-40.


Nuclear localization of SYT, SSX and the synovial sarcoma-associated SYT-SSX fusion proteins.

dos Santos NR, de Bruijn DR, Balemans M, Janssen B, Gärtner F, Lopes JM, de Leeuw B, Geurts van Kessel A.

Hum Mol Genet. 1997 Sep;6(9):1549-58.


Multiple regions of ETO cooperate in transcriptional repression.

Hildebrand D, Tiefenbach J, Heinzel T, Grez M, Maurer AB.

J Biol Chem. 2001 Mar 30;276(13):9889-95. Epub 2001 Jan 9.


The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10.

de Bruijn DR, dos Santos NR, Thijssen J, Balemans M, Debernardi S, Linder B, Young BD, Geurts van Kessel A.

Oncogene. 2001 May 31;20(25):3281-9.


Induction of p21(WAF1/CIP1) by human synovial sarcoma-associated chimeric oncoprotein SYT-SSX1.

Tsuda M, Watanabe T, Seki T, Kimura T, Sawa H, Minami A, Akagi T, Isobe K, Nagashima K, Tanaka S.

Oncogene. 2005 Dec 1;24(54):7984-90.


Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter.

Baker KM, Wei G, Schaffner AE, Ostrowski MC.

J Biol Chem. 2003 May 16;278(20):17876-84. Epub 2003 Mar 10.


The transcriptional corepressor, PELP1, recruits HDAC2 and masks histones using two separate domains.

Choi YB, Ko JK, Shin J.

J Biol Chem. 2004 Dec 3;279(49):50930-41. Epub 2004 Sep 27.


Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.

Otsuki T, Furukawa Y, Ikeda K, Endo H, Yamashita T, Shinohara A, Iwamatsu A, Ozawa K, Liu JM.

Hum Mol Genet. 2001 Nov 1;10(23):2651-60.


Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation.

Harada J, Kokura K, Kanei-Ishii C, Nomura T, Khan MM, Kim Y, Ishii S.

J Biol Chem. 2003 Oct 3;278(40):38998-9005. Epub 2003 Jul 21.


Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF.

Cairns BR, Erdjument-Bromage H, Tempst P, Winston F, Kornberg RD.

Mol Cell. 1998 Nov;2(5):639-51.

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