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Items: 1 to 20 of 101

1.

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome.

Brown V, Jin P, Ceman S, Darnell JC, O'Donnell WT, Tenenbaum SA, Jin X, Feng Y, Wilkinson KD, Keene JD, Darnell RB, Warren ST.

Cell. 2001 Nov 16;107(4):477-87.

2.

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function.

Darnell JC, Jensen KB, Jin P, Brown V, Warren ST, Darnell RB.

Cell. 2001 Nov 16;107(4):489-99.

3.

The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses.

Zalfa F, Giorgi M, Primerano B, Moro A, Di Penta A, Reis S, Oostra B, Bagni C.

Cell. 2003 Feb 7;112(3):317-27.

4.

Evidence that fragile X mental retardation protein is a negative regulator of translation.

Laggerbauer B, Ostareck D, Keidel EM, Ostareck-Lederer A, Fischer U.

Hum Mol Genet. 2001 Feb 15;10(4):329-38.

PMID:
11157796
5.

The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif.

Schaeffer C, Bardoni B, Mandel JL, Ehresmann B, Ehresmann C, Moine H.

EMBO J. 2001 Sep 3;20(17):4803-13.

6.

The fragile X mental retardation protein, FMRP, recognizes G-quartets.

Darnell JC, Warren ST, Darnell RB.

Ment Retard Dev Disabil Res Rev. 2004;10(1):49-52. Review.

PMID:
14994288
7.

The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain.

Aschrafi A, Cunningham BA, Edelman GM, Vanderklish PW.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2180-5. Epub 2005 Jan 31.

8.

New insights into fragile X syndrome: from molecules to neurobehaviors.

Jin P, Warren ST.

Trends Biochem Sci. 2003 Mar;28(3):152-8. Review.

PMID:
12633995
9.
10.

Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes.

Darnell JC, Fraser CE, Mostovetsky O, Stefani G, Jones TA, Eddy SR, Darnell RB.

Genes Dev. 2005 Apr 15;19(8):903-18. Epub 2005 Apr 1.

11.

The RNA binding protein FMRP: new connections and missing links.

Schaeffer C, Beaulande M, Ehresmann C, Ehresmann B, Moine H.

Biol Cell. 2003 May-Jun;95(3-4):221-8. Review.

PMID:
12867085
12.

Fragile X syndrome, the Fragile X related proteins, and animal models.

Hoogeveen AT, Willemsen R, Oostra BA.

Microsc Res Tech. 2002 May 1;57(3):148-55. Review.

PMID:
12112450
13.

The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95.

Todd PK, Mack KJ, Malter JS.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14374-8. Epub 2003 Nov 12.

14.

Regulating a translational regulator: mechanisms cells use to control the activity of the fragile X mental retardation protein.

Denman RB, Dolzhanskaya N, Sung YJ.

Cell Mol Life Sci. 2004 Jul;61(14):1714-28. Review.

PMID:
15241549
15.

The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.

Lu R, Wang H, Liang Z, Ku L, O'donnell WT, Li W, Warren ST, Feng Y.

Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15201-6. Epub 2004 Oct 8.

16.

FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association.

Feng Y, Absher D, Eberhart DE, Brown V, Malter HE, Warren ST.

Mol Cell. 1997 Dec;1(1):109-18.

18.

G-quartet-dependent recognition between the FMRP RGG box and RNA.

Ramos A, Hollingworth D, Pastore A.

RNA. 2003 Oct;9(10):1198-207.

19.
20.

Biology of the fragile X mental retardation protein, an RNA-binding protein.

Khandjian EW.

Biochem Cell Biol. 1999;77(4):331-42. Review.

PMID:
10546896

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