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Items: 1 to 20 of 422

1.

The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex.

Tomoda K, Kubota Y, Arata Y, Mori S, Maeda M, Tanaka T, Yoshida M, Yoneda-Kato N, Kato JY.

J Biol Chem. 2002 Jan 18;277(3):2302-10. Epub 2001 Nov 9.

2.

Direct binding of the signal-transducing adaptor Grb2 facilitates down-regulation of the cyclin-dependent kinase inhibitor p27Kip1.

Sugiyama Y, Tomoda K, Tanaka T, Arata Y, Yoneda-Kato N, Kato J.

J Biol Chem. 2001 Apr 13;276(15):12084-90. Epub 2001 Jan 22.

3.

Multiple functions of Jab1 are required for early embryonic development and growth potential in mice.

Tomoda K, Yoneda-Kato N, Fukumoto A, Yamanaka S, Kato JY.

J Biol Chem. 2004 Oct 8;279(41):43013-8. Epub 2004 Aug 6.

4.

The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression.

Tomoda K, Kato JY, Tatsumi E, Takahashi T, Matsuo Y, Yoneda-Kato N.

Blood. 2005 Jan 15;105(2):775-83. Epub 2004 Sep 7.

5.

Prognostic significance of localized p27Kip1 and potential role of Jab1/CSN5 in pancreatic cancer.

Fukumoto A, Ikeda N, Sho M, Tomoda K, Kanehiro H, Hisanaga M, Tsurui Y, Tsutsumi M, Kato JY, Nakajima Y.

Oncol Rep. 2004 Feb;11(2):277-84.

PMID:
14719054
6.

Jab1/CSN5 induces the cytoplasmic localization and degradation of RUNX3.

Kim JH, Choi JK, Cinghu S, Jang JW, Lee YS, Li YH, Goh YM, Chi XZ, Lee KS, Wee H, Bae SC.

J Cell Biochem. 2009 Jun 1;107(3):557-65. doi: 10.1002/jcb.22157.

PMID:
19350572
7.

JAB1/CSN5 and the COP9 signalosome. A complex situation.

Chamovitz DA, Segal D.

EMBO Rep. 2001 Feb;2(2):96-101. Review.

8.

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1.

Tomoda K, Kubota Y, Kato J.

Nature. 1999 Mar 11;398(6723):160-5.

PMID:
10086358
9.

Jab1 co-activation of c-Jun is abrogated by the serine 10-phosphorylated form of p27Kip1.

Chopra S, Fernandez De Mattos S, Lam EW, Mann DJ.

J Biol Chem. 2002 Sep 6;277(36):32413-6. Epub 2002 Jul 15.

10.
11.

Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1.

Hwang CY, Ryu YS, Chung MS, Kim KD, Park SS, Chae SK, Chae HZ, Kwon KS.

Oncogene. 2004 Nov 25;23(55):8868-75.

PMID:
15480426
12.

Jab1 mediates cytoplasmic localization and degradation of West Nile virus capsid protein.

Oh W, Yang MR, Lee EW, Park KM, Pyo S, Yang JS, Lee HW, Song J.

J Biol Chem. 2006 Oct 6;281(40):30166-74. Epub 2006 Aug 1.

13.

Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1.

Jeon JH, Lee KN, Hwang CY, Kwon KS, You KH, Choi I.

Cancer Res. 2005 Jun 1;65(11):4485-9.

14.

A novel nuclear export signal in Smad1 is essential for its signaling activity.

Xiao Z, Brownawell AM, Macara IG, Lodish HF.

J Biol Chem. 2003 Sep 5;278(36):34245-52. Epub 2003 Jun 23.

15.

Retinoic acid stabilizes p27Kip1 in EBV-immortalized lymphoblastoid B cell lines through enhanced proteasome-dependent degradation of the p45Skp2 and Cks1 proteins.

Zancai P, Dal Col J, Piccinin S, Guidoboni M, Cariati R, Rizzo S, Boiocchi M, Maestro R, Dolcetti R.

Oncogene. 2005 Apr 7;24(15):2483-94.

PMID:
15735731
16.

CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis.

Connor MK, Kotchetkov R, Cariou S, Resch A, Lupetti R, Beniston RG, Melchior F, Hengst L, Slingerland JM.

Mol Biol Cell. 2003 Jan;14(1):201-13.

17.

Functional interaction of the Ras effector RASSF5 with the tyrosine kinase Lck: critical role in nucleocytoplasmic transport and cell cycle regulation.

Kumari G, Singhal PK, Suryaraja R, Mahalingam S.

J Mol Biol. 2010 Mar 19;397(1):89-109. doi: 10.1016/j.jmb.2010.01.005. Epub 2010 Jan 11.

PMID:
20064523
18.

Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1).

Kouvaraki MA, Rassidakis GZ, Tian L, Kumar R, Kittas C, Claret FX.

Cancer Res. 2003 Jun 1;63(11):2977-81.

19.

Overexpression of adenovirus-mediated p27kip1 lacking the Jab1-binding region enhances cytotoxicity and inhibits xenografted human cholangiocarcinoma growth.

Shiraso S, Katayose Y, Yamamoto K, Mizuma M, Yabuuchi S, Oda A, Rikiyama T, Onogawa T, Yoshida H, Hayashi H, Ohtsuka H, Motoi F, Egawa S, Kato J, Unno M.

Anticancer Res. 2009 Jun;29(6):2015-24.

20.

Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1.

Kleemann R, Hausser A, Geiger G, Mischke R, Burger-Kentischer A, Flieger O, Johannes FJ, Roger T, Calandra T, Kapurniotu A, Grell M, Finkelmeier D, Brunner H, Bernhagen J.

Nature. 2000 Nov 9;408(6809):211-6.

PMID:
11089976

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