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Items: 1 to 20 of 194

2.

A Conserved C-terminal Element in the Yeast Doa10 and Human MARCH6 Ubiquitin Ligases Required for Selective Substrate Degradation.

Zattas D, Berk JM, Kreft SG, Hochstrasser M.

J Biol Chem. 2016 Jun 3;291(23):12105-18. doi: 10.1074/jbc.M116.726877. Epub 2016 Apr 11.

PMID:
27068744
3.

Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase.

Deng M, Hochstrasser M.

Nature. 2006 Oct 19;443(7113):827-31.

PMID:
17051211
4.

N-terminal acetylation of the yeast Derlin Der1 is essential for Hrd1 ubiquitin-ligase activity toward luminal ER substrates.

Zattas D, Adle DJ, Rubenstein EM, Hochstrasser M.

Mol Biol Cell. 2013 Apr;24(7):890-900. doi: 10.1091/mbc.E12-11-0838. Epub 2013 Jan 30.

5.

Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways.

Ravid T, Kreft SG, Hochstrasser M.

EMBO J. 2006 Feb 8;25(3):533-43. Epub 2006 Jan 26.

6.

An unusual transmembrane helix in the endoplasmic reticulum ubiquitin ligase Doa10 modulates degradation of its cognate E2 enzyme.

Kreft SG, Hochstrasser M.

J Biol Chem. 2011 Jun 10;286(23):20163-74. doi: 10.1074/jbc.M110.196360. Epub 2011 Apr 5.

7.
8.

Natural substrates of the proteasome and their recognition by the ubiquitin system.

Ulrich HD.

Curr Top Microbiol Immunol. 2002;268:137-74. Review.

PMID:
12083004
9.

Degradation signals recognized by the Ubc6p-Ubc7p ubiquitin-conjugating enzyme pair.

Gilon T, Chomsky O, Kulka RG.

Mol Cell Biol. 2000 Oct;20(19):7214-9.

10.

Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor.

Chen P, Johnson P, Sommer T, Jentsch S, Hochstrasser M.

Cell. 1993 Jul 30;74(2):357-69.

PMID:
8393731
11.

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

Bays NW, Gardner RG, Seelig LP, Joazeiro CA, Hampton RY.

Nat Cell Biol. 2001 Jan;3(1):24-9.

PMID:
11146622
12.

A role for mammalian Ubc6 homologues in ER-associated protein degradation.

Lenk U, Yu H, Walter J, Gelman MS, Hartmann E, Kopito RR, Sommer T.

J Cell Sci. 2002 Jul 15;115(Pt 14):3007-14.

13.

The yeast ERAD-C ubiquitin ligase Doa10 recognizes an intramembrane degron.

Habeck G, Ebner FA, Shimada-Kreft H, Kreft SG.

J Cell Biol. 2015 Apr 27;209(2):261-73. doi: 10.1083/jcb.201408088. Erratum in: J Cell Biol. 2015 May 25;209(4):621. J Cell Biol. 2015 Apr 27;209(2):260.

14.

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum.

Kikkert M, Doolman R, Dai M, Avner R, Hassink G, van Voorden S, Thanedar S, Roitelman J, Chau V, Wiertz E.

J Biol Chem. 2004 Jan 30;279(5):3525-34. Epub 2003 Oct 30.

15.

Protein quality control at the inner nuclear membrane.

Khmelinskii A, Blaszczak E, Pantazopoulou M, Fischer B, Omnus DJ, Le Dez G, Brossard A, Gunnarsson A, Barry JD, Meurer M, Kirrmaier D, Boone C, Huber W, Rabut G, Ljungdahl PO, Knop M.

Nature. 2014 Dec 18;516(7531):410-3. doi: 10.1038/nature14096.

16.

Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase.

Rubenstein EM, Kreft SG, Greenblatt W, Swanson R, Hochstrasser M.

J Cell Biol. 2012 Jun 11;197(6):761-73. doi: 10.1083/jcb.201203061.

17.

Distinct activation of an E2 ubiquitin-conjugating enzyme by its cognate E3 ligases.

Cohen I, Wiener R, Reiss Y, Ravid T.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E625-32. doi: 10.1073/pnas.1415621112. Epub 2015 Feb 2.

18.

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway.

Hiller MM, Finger A, Schweiger M, Wolf DH.

Science. 1996 Sep 20;273(5282):1725-8.

PMID:
8781238
19.

'ER degradation' of a mutant yeast plasma membrane protein by the ubiquitin-proteasome pathway.

Galan JM, Cantegrit B, Garnier C, Namy O, Haguenauer-Tsapis R.

FASEB J. 1998 Mar;12(3):315-23.

PMID:
9506475
20.

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