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Items: 1 to 20 of 200

1.

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

Lim GP, Chu T, Yang F, Beech W, Frautschy SA, Cole GM.

J Neurosci. 2001 Nov 1;21(21):8370-7.

2.

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

Lim GP, Yang F, Chu T, Chen P, Beech W, Teter B, Tran T, Ubeda O, Ashe KH, Frautschy SA, Cole GM.

J Neurosci. 2000 Aug 1;20(15):5709-14.

3.

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.

Yang F, Lim GP, Begum AN, Ubeda OJ, Simmons MR, Ambegaokar SS, Chen PP, Kayed R, Glabe CG, Frautschy SA, Cole GM.

J Biol Chem. 2005 Feb 18;280(7):5892-901.

4.

Transgenic AD model mice, effects of potential anti-AD treatments on inflammation, and pathology.

van Groen T, Miettinen P, Kadish I.

J Alzheimers Dis. 2011;24(2):301-13. doi: 10.3233/JAD-2011-101479.

PMID:
21239852
5.

NSAID and antioxidant prevention of Alzheimer's disease: lessons from in vitro and animal models.

Cole GM, Morihara T, Lim GP, Yang F, Begum A, Frautschy SA.

Ann N Y Acad Sci. 2004 Dec;1035:68-84. Review.

PMID:
15681801
6.

Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.

Kukar T, Prescott S, Eriksen JL, Holloway V, Murphy MP, Koo EH, Golde TE, Nicolle MM.

BMC Neurosci. 2007 Jul 24;8:54.

7.

Anti-inflammatory drug therapy alters beta-amyloid processing and deposition in an animal model of Alzheimer's disease.

Yan Q, Zhang J, Liu H, Babu-Khan S, Vassar R, Biere AL, Citron M, Landreth G.

J Neurosci. 2003 Aug 20;23(20):7504-9.

8.

Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice.

Sivilia S, Lorenzini L, Giuliani A, Gusciglio M, Fernandez M, Baldassarro VA, Mangano C, Ferraro L, Pietrini V, Baroc MF, Viscomi AR, Ottonello S, Villetti G, Imbimbo BP, Calzà L, Giardino L.

BMC Neurosci. 2013 Apr 5;14:44. doi: 10.1186/1471-2202-14-44.

9.

Age-dependent neuroplasticity mechanisms in Alzheimer Tg2576 mice following modulation of brain amyloid-β levels.

Lilja AM, Röjdner J, Mustafiz T, Thomé CM, Storelli E, Gonzalez D, Unger-Lithner C, Greig NH, Nordberg A, Marutle A.

PLoS One. 2013;8(3):e58752. doi: 10.1371/journal.pone.0058752.

10.

Curcumin derivative with the substitution at C-4 position, but not curcumin, is effective against amyloid pathology in APP/PS1 mice.

Yanagisawa D, Ibrahim NF, Taguchi H, Morikawa S, Hirao K, Shirai N, Sogabe T, Tooyama I.

Neurobiol Aging. 2015 Jan;36(1):201-10. doi: 10.1016/j.neurobiolaging.2014.07.041.

PMID:
25179227
11.

Ibuprofen suppresses interleukin-1beta induction of pro-amyloidogenic alpha1-antichymotrypsin to ameliorate beta-amyloid (Abeta) pathology in Alzheimer's models.

Morihara T, Teter B, Yang F, Lim GP, Boudinot S, Boudinot FD, Frautschy SA, Cole GM.

Neuropsychopharmacology. 2005 Jun;30(6):1111-20.

12.

Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology.

Frautschy SA, Hu W, Kim P, Miller SA, Chu T, Harris-White ME, Cole GM.

Neurobiol Aging. 2001 Nov-Dec;22(6):993-1005.

PMID:
11755008
13.

Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.

Jantzen PT, Connor KE, DiCarlo G, Wenk GL, Wallace JL, Rojiani AM, Coppola D, Morgan D, Gordon MN.

J Neurosci. 2002 Mar 15;22(6):2246-54.

14.

Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation.

Xu PX, Wang SW, Yu XL, Su YJ, Wang T, Zhou WW, Zhang H, Wang YJ, Liu RT.

Behav Brain Res. 2014 May 1;264:173-80. doi: 10.1016/j.bbr.2014.02.002.

PMID:
24512768
15.
16.

The effect of focal brain injury on beta-amyloid plaque deposition, inflammation and synapses in the APP/PS1 mouse model of Alzheimer's disease.

Collins JM, King AE, Woodhouse A, Kirkcaldie MT, Vickers JC.

Exp Neurol. 2015 May;267:219-29. doi: 10.1016/j.expneurol.2015.02.034.

PMID:
25747037
17.

Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice.

Nikolic WV, Hou H, Town T, Zhu Y, Giunta B, Sanberg CD, Zeng J, Luo D, Ehrhart J, Mori T, Sanberg PR, Tan J.

Stem Cells Dev. 2008 Jun;17(3):423-39. doi: 10.1089/scd.2008.0018.

18.

Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease.

Calabrese V, Butterfield DA, Stella AM.

Ital J Biochem. 2003 Dec;52(4):177-81. Review.

PMID:
15141484
19.

Decreasing oxidative stress and neuroinflammation with a multifunctional peptide rescues memory deficits in mice with Alzheimer disease.

Zhou WW, Lu S, Su YJ, Xue D, Yu XL, Wang SW, Zhang H, Xu PX, Xie XX, Liu RT.

Free Radic Biol Med. 2014 Sep;74:50-63. doi: 10.1016/j.freeradbiomed.2014.06.013.

PMID:
24960578
20.

Chronic intranasal treatment with an anti-Aβ(30-42) scFv antibody ameliorates amyloid pathology in a transgenic mouse model of Alzheimer's disease.

Cattepoel S, Hanenberg M, Kulic L, Nitsch RM.

PLoS One. 2011 Apr 5;6(4):e18296. doi: 10.1371/journal.pone.0018296.

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