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Effects of cocaine and its major metabolites on the HERG-encoded potassium channel.

Ferreira S, Crumb WJ Jr, Carlton CG, Clarkson CW.

J Pharmacol Exp Ther. 2001 Oct;299(1):220-6.


Cocaine blocks HERG, but not KvLQT1+minK, potassium channels.

Zhang S, Rajamani S, Chen Y, Gong Q, Rong Y, Zhou Z, Ruoho A, January CT.

Mol Pharmacol. 2001 May;59(5):1069-76.


Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines.

Taglialatela M, Pannaccione A, Castaldo P, Giorgio G, Zhou Z, January CT, Genovese A, Marone G, Annunziato L.

Mol Pharmacol. 1998 Jul;54(1):113-21.


Inhibition of human ether-a-go-go potassium channels by cocaine.

O'Leary ME.

Mol Pharmacol. 2001 Feb;59(2):269-77.


Spironolactone and its main metabolite, canrenoic acid, block human ether-a-go-go-related gene channels.

Caballero R, Moreno I, González T, Arias C, Valenzuela C, Delpón E, Tamargo J.

Circulation. 2003 Feb 18;107(6):889-95.


Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics.

Volberg WA, Koci BJ, Su W, Lin J, Zhou J.

J Pharmacol Exp Ther. 2002 Jul;302(1):320-7.


Effects of Na+ channel blocker, pilsicainide, on HERG current expressed in HEK-293 cells.

Wu LM, Orikabe M, Hirano Y, Kawano S, Hiraoka M.

J Cardiovasc Pharmacol. 2003 Sep;42(3):410-8.


Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline.

Teschemacher AG, Seward EP, Hancox JC, Witchel HJ.

Br J Pharmacol. 1999 Sep;128(2):479-85.


The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes.

Suessbrich H, Schönherr R, Heinemann SH, Attali B, Lang F, Busch AE.

Br J Pharmacol. 1997 Mar;120(5):968-74.


The antipsychotic agent sertindole is a high affinity antagonist of the human cardiac potassium channel HERG.

Rampe D, Murawsky MK, Grau J, Lewis EW.

J Pharmacol Exp Ther. 1998 Aug;286(2):788-93.


The anti-malarial drug halofantrine and its metabolite N-desbutylhalofantrine block HERG potassium channels.

Mbai M, Rajamani S, January CT.

Cardiovasc Res. 2002 Sep;55(4):799-805.


Influence of opioid agonists on cardiac human ether-a-go-go-related gene K(+) currents.

Katchman AN, McGroary KA, Kilborn MJ, Kornick CA, Manfredi PL, Woosley RL, Ebert SN.

J Pharmacol Exp Ther. 2002 Nov;303(2):688-94.


Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG.

Kang J, Wang L, Chen XL, Triggle DJ, Rampe D.

Mol Pharmacol. 2001 Jan;59(1):122-6.


Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature.

Zhou Z, Gong Q, Ye B, Fan Z, Makielski JC, Robertson GA, January CT.

Biophys J. 1998 Jan;74(1):230-41.


Open channel block of HERG K(+) channels by vesnarinone.

Kamiya K, Mitcheson JS, Yasui K, Kodama I, Sanguinetti MC.

Mol Pharmacol. 2001 Aug;60(2):244-53.


Altered gating of HERG potassium channels by cobalt and lanthanum.

Sanchez-Chapula JA, Sanguinetti MC.

Pflugers Arch. 2000 Jun;440(2):264-74.


Interactions of the 5-hydroxytryptamine 3 antagonist class of antiemetic drugs with human cardiac ion channels.

Kuryshev YA, Brown AM, Wang L, Benedict CR, Rampe D.

J Pharmacol Exp Ther. 2000 Nov;295(2):614-20.


Molecular determinants of voltage-dependent human ether-a-go-go related gene (HERG) K+ channel block.

Sánchez-Chapula JA, Navarro-Polanco RA, Culberson C, Chen J, Sanguinetti MC.

J Biol Chem. 2002 Jun 28;277(26):23587-95. Epub 2002 Apr 17.

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