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Items: 1 to 20 of 289

1.

Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.

Steinkellner H, Rabot S, Freywald C, Nobis E, Scharf G, Chabicovsky M, Knasmüller S, Kassie F.

Mutat Res. 2001 Sep 1;480-481:285-97. Review.

PMID:
11506821
2.

Chemoprevention of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced colonic and hepatic preneoplastic lesions in the F344 rat by cruciferous vegetables administered simultaneously with the carcinogen.

Kassie F, Uhl M, Rabot S, Grasl-Kraupp B, Verkerk R, Kundi M, Chabicovsky M, Schulte-Hermann R, Knasmüller S.

Carcinogenesis. 2003 Feb;24(2):255-61.

PMID:
12584175
3.

Effects of consumption of Brussels sprouts on intestinal and lymphocytic glutathione S-transferases in humans.

Nijhoff WA, Grubben MJ, Nagengast FM, Jansen JB, Verhagen H, van Poppel G, Peters WH.

Carcinogenesis. 1995 Sep;16(9):2125-8.

PMID:
7554064
4.
5.

Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism.

Talalay P, Fahey JW.

J Nutr. 2001 Nov;131(11 Suppl):3027S-33S. Review.

PMID:
11694642
6.

Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver.

Perocco P, Bronzetti G, Canistro D, Valgimigli L, Sapone A, Affatato A, Pedulli GF, Pozzetti L, Broccoli M, Iori R, Barillari J, Sblendorio V, Legator MS, Paolini M, Abdel-Rahman SZ.

Mutat Res. 2006 Mar 20;595(1-2):125-36.

PMID:
16442570
7.

A principal mechanism for the cancer chemopreventive activity of phenethyl isothiocyanate is modulation of carcinogen metabolism.

Ioannides C, Konsue N.

Drug Metab Rev. 2015 Aug;47(3):356-73. doi: 10.3109/03602532.2015.1058819. Epub 2015 Jun 29. Review.

PMID:
26119477
8.

4-Methylsulfanyl-3-butenyl isothiocyanate derived from glucoraphasatin is a potent inducer of rat hepatic phase II enzymes and a potential chemopreventive agent.

Abdull Razis AF, De Nicola GR, Pagnotta E, Iori R, Ioannides C.

Arch Toxicol. 2012 Feb;86(2):183-94. doi: 10.1007/s00204-011-0750-x. Epub 2011 Sep 30.

PMID:
21960141
9.

Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention.

Buetler TM, Bammler TK, Hayes JD, Eaton DL.

Cancer Res. 1996 May 15;56(10):2306-13.

10.

Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables.

Shapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P.

Cancer Epidemiol Biomarkers Prev. 1998 Dec;7(12):1091-100.

11.
12.

Heat treatment of Brussels sprouts retains their ability to induce detoxification enzyme expression in vitro and in vivo.

Robbins MG, Andersen G, Somoza V, Eshelman BD, Barnes DM, Hanlon PR.

J Food Sci. 2011 Apr;76(3):C454-61. doi: 10.1111/j.1750-3841.2011.02105.x.

PMID:
21535814
13.

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens.

Fahey JW, Zhang Y, Talalay P.

Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10367-72.

14.

Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.

Higdon JV, Delage B, Williams DE, Dashwood RH.

Pharmacol Res. 2007 Mar;55(3):224-36. Epub 2007 Jan 25. Review.

15.
16.

Cruciferous vegetables: cancer protective mechanisms of glucosinolate hydrolysis products and selenium.

Keck AS, Finley JW.

Integr Cancer Ther. 2004 Mar;3(1):5-12. Review.

PMID:
15035868
17.

A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.

Abdull Razis AF, De Nicola GR, Pagnotta E, Iori R, Ioannides C.

Eur J Nutr. 2013 Apr;52(3):1279-85. doi: 10.1007/s00394-012-0397-2. Epub 2012 Jun 19.

PMID:
22710810
18.

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure.

Zhang Y, Talalay P, Cho CG, Posner GH.

Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2399-403.

19.

Potent induction of phase 2 enzymes in human prostate cells by sulforaphane.

Brooks JD, Paton VG, Vidanes G.

Cancer Epidemiol Biomarkers Prev. 2001 Sep;10(9):949-54.

20.

Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man.

Murray S, Lake BG, Gray S, Edwards AJ, Springall C, Bowey EA, Williamson G, Boobis AR, Gooderham NJ.

Carcinogenesis. 2001 Sep;22(9):1413-20.

PMID:
11532863

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