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Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut.

Melmed G, Thomas LS, Lee N, Tesfay SY, Lukasek K, Michelsen KS, Zhou Y, Hu B, Arditi M, Abreu MT.

J Immunol. 2003 Feb 1;170(3):1406-15.


Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4.

Medvedev AE, Henneke P, Schromm A, Lien E, Ingalls R, Fenton MJ, Golenbock DT, Vogel SN.

J Immunol. 2001 Aug 15;167(4):2257-67.


Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2.

Hirschfeld M, Kirschning CJ, Schwandner R, Wesche H, Weis JH, Wooten RM, Weis JJ.

J Immunol. 1999 Sep 1;163(5):2382-6.


Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent.

Huang LY, Aliberti J, Leifer CA, Segal DM, Sher A, Golenbock DT, Golding B.

J Immunol. 2003 Aug 1;171(3):1441-6.


Signaling events induced by lipopolysaccharide-activated toll-like receptor 2.

Yang RB, Mark MR, Gurney AL, Godowski PJ.

J Immunol. 1999 Jul 15;163(2):639-43.


Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes.

Zhang FX, Kirschning CJ, Mancinelli R, Xu XP, Jin Y, Faure E, Mantovani A, Rothe M, Muzio M, Arditi M.

J Biol Chem. 1999 Mar 19;274(12):7611-4.


Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses.

Means TK, Jones BW, Schromm AB, Shurtleff BA, Smith JA, Keane J, Golenbock DT, Vogel SN, Fenton MJ.

J Immunol. 2001 Mar 15;166(6):4074-82.


Induction of bacterial lipoprotein tolerance is associated with suppression of toll-like receptor 2 expression.

Wang JH, Doyle M, Manning BJ, Di Wu Q, Blankson S, Redmond HP.

J Biol Chem. 2002 Sep 27;277(39):36068-75. Epub 2002 Jul 19.


Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.

Hajjar AM, O'Mahony DS, Ozinsky A, Underhill DM, Aderem A, Klebanoff SJ, Wilson CB.

J Immunol. 2001 Jan 1;166(1):15-9.


Expression and function of Toll-like receptors 2 and 4 in human keratinocytes.

Pivarcsi A, Bodai L, Réthi B, Kenderessy-Szabó A, Koreck A, Széll M, Beer Z, Bata-Csörgoo Z, Magócsi M, Rajnavölgyi E, Dobozy A, Kemény L.

Int Immunol. 2003 Jun;15(6):721-30.


Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells.

Vabulas RM, Ahmad-Nejad P, da Costa C, Miethke T, Kirschning CJ, Häcker H, Wagner H.

J Biol Chem. 2001 Aug 17;276(33):31332-9. Epub 2001 Jun 11.


Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies.

Raschi E, Testoni C, Bosisio D, Borghi MO, Koike T, Mantovani A, Meroni PL.

Blood. 2003 May 1;101(9):3495-500. Epub 2003 Jan 16.


A dominant role of Toll-like receptor 4 in the signaling of apoptosis in bacteria-faced macrophages.

Haase R, Kirschning CJ, Sing A, Schröttner P, Fukase K, Kusumoto S, Wagner H, Heesemann J, Ruckdeschel K.

J Immunol. 2003 Oct 15;171(8):4294-303.


The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors.

Means TK, Lien E, Yoshimura A, Wang S, Golenbock DT, Fenton MJ.

J Immunol. 1999 Dec 15;163(12):6748-55.

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