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Items: 1 to 20 of 232

1.

26S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer.

Shah SA, Potter MW, McDade TP, Ricciardi R, Perugini RA, Elliott PJ, Adams J, Callery MP.

J Cell Biochem. 2001 Apr 2-27;82(1):110-22.

PMID:
11400168
2.

Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition.

Cusack JC Jr, Liu R, Houston M, Abendroth K, Elliott PJ, Adams J, Baldwin AS Jr.

Cancer Res. 2001 May 1;61(9):3535-40.

3.

Chemosensitization of pancreatic cancer by inhibition of the 26S proteasome.

Bold RJ, Virudachalam S, McConkey DJ.

J Surg Res. 2001 Sep;100(1):11-7.

PMID:
11516199
4.

The proteasome inhibitor bortezomib enhances the activity of docetaxel in orthotopic human pancreatic tumor xenografts.

Nawrocki ST, Sweeney-Gotsch B, Takamori R, McConkey DJ.

Mol Cancer Ther. 2004 Jan;3(1):59-70. Erratum in: Mol Cancer Ther. 2009 Feb;8(2):479.

5.

Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines.

Ling YH, Liebes L, Jiang JD, Holland JF, Elliott PJ, Adams J, Muggia FM, Perez-Soler R.

Clin Cancer Res. 2003 Mar;9(3):1145-54.

6.

Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.

Russo SM, Tepper JE, Baldwin AS Jr, Liu R, Adams J, Elliott P, Cusack JC Jr.

Int J Radiat Oncol Biol Phys. 2001 May 1;50(1):183-93.

PMID:
11316563
7.

Proteasome inhibition sensitizes non-small-cell lung cancer to gemcitabine-induced apoptosis.

Denlinger CE, Rundall BK, Keller MD, Jones DR.

Ann Thorac Surg. 2004 Oct;78(4):1207-14; discussion 1207-14.

PMID:
15464472
8.

Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-kappaB mutations or activation of the CD30, CD40, and RANK receptors.

Zheng B, Georgakis GV, Li Y, Bharti A, McConkey D, Aggarwal BB, Younes A.

Clin Cancer Res. 2004 May 1;10(9):3207-15. Erratum in: Clin Cancer Res. 2014 Jun 1;20(11):3044.

9.

Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells.

Nawrocki ST, Carew JS, Pino MS, Highshaw RA, Andtbacka RH, Dunner K Jr, Pal A, Bornmann WG, Chiao PJ, Huang P, Xiong H, Abbruzzese JL, McConkey DJ.

Cancer Res. 2006 Apr 1;66(7):3773-81.

10.

Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis.

Bota DA, Alexandru D, Keir ST, Bigner D, Vredenburgh J, Friedman HS.

J Neurosurg. 2013 Dec;119(6):1415-23. doi: 10.3171/2013.7.JNS1323. Epub 2013 Oct 4.

11.

The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors in vivo.

Kamat AM, Karashima T, Davis DW, Lashinger L, Bar-Eli M, Millikan R, Shen Y, Dinney CP, McConkey DJ.

Mol Cancer Ther. 2004 Mar;3(3):279-90.

12.

Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells.

Khanbolooki S, Nawrocki ST, Arumugam T, Andtbacka R, Pino MS, Kurzrock R, Logsdon CD, Abbruzzese JL, McConkey DJ.

Mol Cancer Ther. 2006 Sep;5(9):2251-60.

13.

Proteasome inhibitor PS-341 causes cell growth arrest and apoptosis in human glioblastoma multiforme (GBM).

Yin D, Zhou H, Kumagai T, Liu G, Ong JM, Black KL, Koeffler HP.

Oncogene. 2005 Jan 13;24(3):344-54.

PMID:
15531918
14.

Proteasome inhibition in cancer: development of PS-341.

Adams J.

Semin Oncol. 2001 Dec;28(6):613-9. Review.

PMID:
11740819
15.

Anti-tumor activity of the proteasome inhibitor bortezomib in gastric cancer.

Nakata W, Hayakawa Y, Nakagawa H, Sakamoto K, Kinoshita H, Takahashi R, Hirata Y, Maeda S, Koike K.

Int J Oncol. 2011 Dec;39(6):1529-36. doi: 10.3892/ijo.2011.1141. Epub 2011 Jul 22.

PMID:
21785822
16.

Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma.

Sunwoo JB, Chen Z, Dong G, Yeh N, Crowl Bancroft C, Sausville E, Adams J, Elliott P, Van Waes C.

Clin Cancer Res. 2001 May;7(5):1419-28.

17.

Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts.

Williams S, Pettaway C, Song R, Papandreou C, Logothetis C, McConkey DJ.

Mol Cancer Ther. 2003 Sep;2(9):835-43.

18.

The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

Hideshima T, Richardson P, Chauhan D, Palombella VJ, Elliott PJ, Adams J, Anderson KC.

Cancer Res. 2001 Apr 1;61(7):3071-6.

19.
20.

Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress.

Fribley A, Wang CY.

Cancer Biol Ther. 2006 Jul;5(7):745-8. Epub 2006 Jul 1.

PMID:
16861900

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