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Items: 1 to 20 of 159

1.

Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1.

Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES.

J Biol Chem. 2001 Jul 27;276(30):28309-13. Epub 2001 Jun 4.

2.

Pro-apoptotic proteins released from the mitochondria regulate the protein composition and caspase-processing activity of the native Apaf-1/caspase-9 apoptosome complex.

Twiddy D, Brown DG, Adrain C, Jukes R, Martin SJ, Cohen GM, MacFarlane M, Cain K.

J Biol Chem. 2004 May 7;279(19):19665-82. Epub 2004 Mar 1.

3.

The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis.

Lauber K, Appel HA, Schlosser SF, Gregor M, Schulze-Osthoff K, Wesselborg S.

J Biol Chem. 2001 Aug 10;276(32):29772-81. Epub 2001 May 31.

4.

CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis.

Razmara M, Srinivasula SM, Wang L, Poyet JL, Geddes BJ, DiStefano PS, Bertin J, Alnemri ES.

J Biol Chem. 2002 Apr 19;277(16):13952-8. Epub 2002 Jan 30.

5.

Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis.

Geddes BJ, Wang L, Huang WJ, Lavellee M, Manji GA, Brown M, Jurman M, Cao J, Morgenstern J, Merriam S, Glucksmann MA, DiStefano PS, Bertin J.

Biochem Biophys Res Commun. 2001 Jun 1;284(1):77-82.

PMID:
11374873
6.

TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.

Pathan N, Marusawa H, Krajewska M, Matsuzawa S, Kim H, Okada K, Torii S, Kitada S, Krajewski S, Welsh K, Pio F, Godzik A, Reed JC.

J Biol Chem. 2001 Aug 24;276(34):32220-9. Epub 2001 Jun 14.

7.

Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1.

Day CL, Dupont C, Lackmann M, Vaux DL, Hinds MG.

Cell Death Differ. 1999 Nov;6(11):1125-32.

9.

Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade.

Droin N, Beauchemin M, Solary E, Bertrand R.

Cancer Res. 2000 Dec 15;60(24):7039-47.

10.

Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c.

Martin MC, Allan LA, Lickrish M, Sampson C, Morrice N, Clarke PR.

J Biol Chem. 2005 Apr 15;280(15):15449-55. Epub 2005 Feb 9.

11.

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization.

Srinivasula SM, Ahmad M, Fernandes-Alnemri T, Alnemri ES.

Mol Cell. 1998 Jun;1(7):949-57.

12.

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1.

Qin H, Srinivasula SM, Wu G, Fernandes-Alnemri T, Alnemri ES, Shi Y.

Nature. 1999 Jun 10;399(6736):549-57.

PMID:
10376594
13.

WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation.

Hu Y, Ding L, Spencer DM, Núñez G.

J Biol Chem. 1998 Dec 11;273(50):33489-94.

14.

Neuronal apoptosis-inhibitory protein does not interact with Smac and requires ATP to bind caspase-9.

Davoodi J, Lin L, Kelly J, Liston P, MacKenzie AE.

J Biol Chem. 2004 Sep 24;279(39):40622-8. Epub 2004 Jul 26.

15.

Apaf-1 is a mediator of E2F-1-induced apoptosis.

Furukawa Y, Nishimura N, Furukawa Y, Satoh M, Endo H, Iwase S, Yamada H, Matsuda M, Kano Y, Nakamura M.

J Biol Chem. 2002 Oct 18;277(42):39760-8. Epub 2002 Jul 30.

16.
17.

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB.

Inohara N, Koseki T, del Peso L, Hu Y, Yee C, Chen S, Carrio R, Merino J, Liu D, Ni J, Núñez G.

J Biol Chem. 1999 May 21;274(21):14560-7.

18.

Interaction with Sug1 enables Ipaf ubiquitination leading to caspase 8 activation and cell death.

Kumar Y, Radha V, Swarup G.

Biochem J. 2010 Mar 15;427(1):91-104. doi: 10.1042/BJ20091349.

PMID:
20085538
19.

Involvement of caspase 1 and its activator Ipaf upstream of mitochondrial events in apoptosis.

Thalappilly S, Sadasivam S, Radha V, Swarup G.

FEBS J. 2006 Jun;273(12):2766-78.

20.

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