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Items: 1 to 20 of 116

1.

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans.

Rudolph KL, Millard M, Bosenberg MW, DePinho RA.

Nat Genet. 2001 Jun;28(2):155-9.

PMID:
11381263
2.
3.

Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma.

Farazi PA, Glickman J, Jiang S, Yu A, Rudolph KL, DePinho RA.

Cancer Res. 2003 Aug 15;63(16):5021-7.

4.

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

González-Suárez E, Samper E, Flores JM, Blasco MA.

Nat Genet. 2000 Sep;26(1):114-7.

5.

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis.

Chin L, Artandi SE, Shen Q, Tam A, Lee SL, Gottlieb GJ, Greider CW, DePinho RA.

Cell. 1999 May 14;97(4):527-38.

6.
7.

Telomere dysfunction: multiple paths to the same end.

Harrington L, Robinson MO.

Oncogene. 2002 Jan 21;21(4):592-7. Review.

8.

Human telomerase reverse transcriptase, p53 and Ki-67 expression and apoptosis in colorectal serrated adenoma.

Oka S, Tanaka S, Hiyama T, Kitadai Y, Yoshihara M, Shimamoto F, Haruma K, Chayama K.

Scand J Gastroenterol. 2002 Oct;37(10):1194-200.

PMID:
12408525
9.

Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease.

Lechel A, Holstege H, Begus Y, Schienke A, Kamino K, Lehmann U, Kubicka S, Schirmacher P, Jonkers J, Rudolph KL.

Gastroenterology. 2007 Apr;132(4):1465-75. Epub 2007 Jan 26.

PMID:
17433324
10.

Chromosomal end fusion resulting from telomere erosion increases susceptibility to radiation via multinucleation: effect of p53.

Ju YJ, Park JE, Juhn KM, Jeong J, Yun M, Park MJ, Park GH, Choi KY, Cho MH, Wong KK, Park WB, Lee KH.

Int J Oncol. 2006 Oct;29(4):753-63.

PMID:
16964373
11.

Telomerase inhibition by an siRNA directed against hTERT leads to telomere attrition in HT29 cells.

de Souza Nascimento P, Alves G, Fiedler W.

Oncol Rep. 2006 Aug;16(2):423-8.

PMID:
16820926
12.

Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes.

Argilla D, Chin K, Singh M, Hodgson JG, Bosenberg M, de Solórzano CO, Lockett S, DePinho RA, Gray J, Hanahan D.

Cancer Cell. 2004 Oct;6(4):373-85.

13.

Telomerase activity and hTERT mRNA in development and progression of adenoma to colorectal cancer.

Kanamaru T, Tanaka K, Kotani J, Ueno K, Yamamoto M, Idei Y, Hisatomi H, Takeyama Y.

Int J Mol Med. 2002 Aug;10(2):205-10.

PMID:
12119560
14.

High levels of telomere dysfunction bestow a selective disadvantage during the progression of human oral squamous cell carcinoma.

Gordon KE, Ireland H, Roberts M, Steeghs K, McCaul JA, MacDonald DG, Parkinson EK.

Cancer Res. 2003 Jan 15;63(2):458-67.

15.

Increased p53 activity does not accelerate telomere-driven ageing.

García-Cao I, García-Cao M, Tomás-Loba A, Martín-Caballero J, Flores JM, Klatt P, Blasco MA, Serrano M.

EMBO Rep. 2006 May;7(5):546-52. Epub 2006 Mar 31.

16.

Mechanisms of carcinogenesis and the mutant mouse.

Williams BO, Jacks T.

Curr Opin Genet Dev. 1996 Feb;6(1):65-70. Review.

PMID:
8791481
17.

Telomere attrition predominantly occurs in precursor lesions during in vivo carcinogenic process of the uterine cervix.

Zhang A, Wang J, Zheng B, Fang X, Angström T, Liu C, Li X, Erlandsson F, Björkholm M, Nordenskjörd M, Gruber A, Wallin KL, Xu D.

Oncogene. 2004 Sep 23;23(44):7441-7.

PMID:
15318175
18.

Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.

Begus-Nahrmann Y, Hartmann D, Kraus J, Eshraghi P, Scheffold A, Grieb M, Rasche V, Schirmacher P, Lee HW, Kestler HA, Lechel A, Rudolph KL.

J Clin Invest. 2012 Jun;122(6):2283-8. doi: 10.1172/JCI61745. Epub 2012 May 24.

19.

Telomeres and telomerase in cancer stem cells.

Ju Z, Rudolph KL.

Eur J Cancer. 2006 Jun;42(9):1197-203. Epub 2006 Apr 27. Review.

PMID:
16644207
20.

Telomere shortening and telomerase expression during multistage carcinogenesis of intraductal papillary mucinous neoplasms of the pancreas.

Hashimoto Y, Murakami Y, Uemura K, Hayashidani Y, Sudo T, Ohge H, Fukuda E, Shimamoto F, Sueda T, Hiyama E.

J Gastrointest Surg. 2008 Jan;12(1):17-28; discussion 28-9.

PMID:
17960465

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