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Items: 1 to 20 of 174


Lefty proteins exhibit unique processing and activate the MAPK pathway.

Ulloa L, Creemers JW, Roy S, Liu S, Mason J, Tabibzadeh S.

J Biol Chem. 2001 Jun 15;276(24):21387-96. Epub 2001 Feb 20.


Processing of transforming growth factor beta 1 precursor by human furin convertase.

Dubois CM, Laprise MH, Blanchette F, Gentry LE, Leduc R.

J Biol Chem. 1995 May 5;270(18):10618-24.


Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos.

Meno C, Saijoh Y, Fujii H, Ikeda M, Yokoyama T, Yokoyama M, Toyoda Y, Hamada H.

Nature. 1996 May 9;381(6578):151-5.


Stra3/lefty, a retinoic acid-inducible novel member of the transforming growth factor-beta superfamily.

Oulad-Abdelghani M, Chazaud C, Bouillet P, Mattei MG, Dollé P, Chambon P.

Int J Dev Biol. 1998 Jan;42(1):23-32.


Activation of human furin precursor processing endoprotease occurs by an intramolecular autoproteolytic cleavage.

Leduc R, Molloy SS, Thorne BA, Thomas G.

J Biol Chem. 1992 Jul 15;267(20):14304-8.


Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-beta-independent mechanism.

Rodríguez-Vita J, Sánchez-López E, Esteban V, Rupérez M, Egido J, Ruiz-Ortega M.

Circulation. 2005 May 17;111(19):2509-17. Epub 2005 May 9.


Lefty at the crossroads of "stemness" and differentiative events.

Tabibzadeh S, Hemmati-Brivanlou A.

Stem Cells. 2006 Sep;24(9):1998-2006. Epub 2006 May 25. Review.


Smad5 is essential for left-right asymmetry in mice.

Chang H, Zwijsen A, Vogel H, Huylebroeck D, Matzuk MM.

Dev Biol. 2000 Mar 1;219(1):71-8.


Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation.

Yoo J, Ghiassi M, Jirmanova L, Balliet AG, Hoffman B, Fornace AJ Jr, Liebermann DA, Bottinger EP, Roberts AB.

J Biol Chem. 2003 Oct 31;278(44):43001-7. Epub 2003 Aug 21.


Site-directed mutagenesis, proteolytic cleavage, and activation of human proheparanase.

Abboud-Jarrous G, Rangini-Guetta Z, Aingorn H, Atzmon R, Elgavish S, Peretz T, Vlodavsky I.

J Biol Chem. 2005 Apr 8;280(14):13568-75. Epub 2005 Jan 19.


Transforming growth factor-beta-mediated chondrogenesis of human mesenchymal progenitor cells involves N-cadherin and mitogen-activated protein kinase and Wnt signaling cross-talk.

Tuli R, Tuli S, Nandi S, Huang X, Manner PA, Hozack WJ, Danielson KG, Hall DJ, Tuan RS.

J Biol Chem. 2003 Oct 17;278(42):41227-36. Epub 2003 Jul 31.


The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis.

Siegfried G, Basak A, Cromlish JA, Benjannet S, Marcinkiewicz J, Chrétien M, Seidah NG, Khatib AM.

J Clin Invest. 2003 Jun;111(11):1723-32.

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