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Items: 1 to 20 of 125

1.

XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair.

Whitehouse CJ, Taylor RM, Thistlethwaite A, Zhang H, Karimi-Busheri F, Lasko DD, Weinfeld M, Caldecott KW.

Cell. 2001 Jan 12;104(1):107-17.

2.

DNA 3'-phosphatase activity is critical for rapid global rates of single-strand break repair following oxidative stress.

Breslin C, Caldecott KW.

Mol Cell Biol. 2009 Sep;29(17):4653-62. doi: 10.1128/MCB.00677-09. Epub 2009 Jun 22.

3.

The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks.

Loizou JI, El-Khamisy SF, Zlatanou A, Moore DJ, Chan DW, Qin J, Sarno S, Meggio F, Pinna LA, Caldecott KW.

Cell. 2004 Apr 2;117(1):17-28.

4.

XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage.

Hanssen-Bauer A, Solvang-Garten K, Sundheim O, Peña-Diaz J, Andersen S, Slupphaug G, Krokan HE, Wilson DM 3rd, Akbari M, Otterlei M.

Environ Mol Mutagen. 2011 Oct;52(8):623-35. doi: 10.1002/em.20663. Epub 2011 Jul 22.

5.

Repair of DNA strand gaps and nicks containing 3'-phosphate and 5'-hydroxyl termini by purified mammalian enzymes.

Karimi-Busheri F, Lee J, Tomkinson AE, Weinfeld M.

Nucleic Acids Res. 1998 Oct 1;26(19):4395-400.

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8.

Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions.

Plo I, Liao ZY, Barceló JM, Kohlhagen G, Caldecott KW, Weinfeld M, Pommier Y.

DNA Repair (Amst). 2003 Oct 7;2(10):1087-100.

PMID:
13679147
9.

XRCC1 stimulates polynucleotide kinase by enhancing its damage discrimination and displacement from DNA repair intermediates.

Mani RS, Fanta M, Karimi-Busheri F, Silver E, Virgen CA, Caldecott KW, Cass CE, Weinfeld M.

J Biol Chem. 2007 Sep 21;282(38):28004-13. Epub 2007 Jul 23.

10.

Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV.

Koch CA, Agyei R, Galicia S, Metalnikov P, O'Donnell P, Starostine A, Weinfeld M, Durocher D.

EMBO J. 2004 Oct 1;23(19):3874-85. Epub 2004 Sep 23.

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12.

Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway.

Audebert M, Salles B, Weinfeld M, Calsou P.

J Mol Biol. 2006 Feb 17;356(2):257-65. Epub 2005 Nov 28.

PMID:
16364363
13.

Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining.

Chappell C, Hanakahi LA, Karimi-Busheri F, Weinfeld M, West SC.

EMBO J. 2002 Jun 3;21(11):2827-32.

14.

NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells.

Das A, Wiederhold L, Leppard JB, Kedar P, Prasad R, Wang H, Boldogh I, Karimi-Busheri F, Weinfeld M, Tomkinson AE, Wilson SH, Mitra S, Hazra TK.

DNA Repair (Amst). 2006 Dec 9;5(12):1439-48. Epub 2006 Sep 18.

15.

A cell cycle-specific requirement for the XRCC1 BRCT II domain during mammalian DNA strand break repair.

Taylor RM, Moore DJ, Whitehouse J, Johnson P, Caldecott KW.

Mol Cell Biol. 2000 Jan;20(2):735-40.

16.

Enzyme action at 3' termini of ionizing radiation-induced DNA strand breaks.

Henner WD, Grunberg SM, Haseltine WA.

J Biol Chem. 1983 Dec 25;258(24):15198-205.

17.

Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1.

Iftner T, Elbel M, Schopp B, Hiller T, Loizou JI, Caldecott KW, Stubenrauch F.

EMBO J. 2002 Sep 2;21(17):4741-8.

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19.

AP endonuclease-independent DNA base excision repair in human cells.

Wiederhold L, Leppard JB, Kedar P, Karimi-Busheri F, Rasouli-Nia A, Weinfeld M, Tomkinson AE, Izumi T, Prasad R, Wilson SH, Mitra S, Hazra TK.

Mol Cell. 2004 Jul 23;15(2):209-20.

20.

Polynucleotide kinase as a potential target for enhancing cytotoxicity by ionizing radiation and topoisomerase I inhibitors.

Bernstein NK, Karimi-Busheri F, Rasouli-Nia A, Mani R, Dianov G, Glover JN, Weinfeld M.

Anticancer Agents Med Chem. 2008 May;8(4):358-67. Review.

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