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Items: 1 to 20 of 154

1.
2.

Activation of Paneth cell alpha-defensins in mouse small intestine.

Ayabe T, Satchell DP, Pesendorfer P, Tanabe H, Wilson CL, Hagen SJ, Ouellette AJ.

J Biol Chem. 2002 Feb 15;277(7):5219-28. Epub 2001 Dec 3.

3.

Paneth cells and innate immunity in the crypt microenvironment.

Ouellette AJ.

Gastroenterology. 1997 Nov;113(5):1779-84. Review.

PMID:
9352884
4.

Enteric defensins: antibiotic peptide components of intestinal host defense.

Selsted ME, Miller SI, Henschen AH, Ouellette AJ.

J Cell Biol. 1992 Aug;118(4):929-36.

5.

Cryptdins: antimicrobial defensins of the murine small intestine.

Eisenhauer PB, Harwig SS, Lehrer RI.

Infect Immun. 1992 Sep;60(9):3556-65.

6.

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria.

Ayabe T, Satchell DP, Wilson CL, Parks WC, Selsted ME, Ouellette AJ.

Nat Immunol. 2000 Aug;1(2):113-8.

PMID:
11248802
7.
8.

Alpha-defensins in enteric innate immunity: functional Paneth cell alpha-defensins in mouse colonic lumen.

Mastroianni JR, Ouellette AJ.

J Biol Chem. 2009 Oct 9;284(41):27848-56. doi: 10.1074/jbc.M109.050773. Epub 2009 Aug 17.

9.

Paneth cell defensins: endogenous peptide components of intestinal host defense.

Ouellette AJ, Selsted ME.

FASEB J. 1996 Sep;10(11):1280-9. Review.

PMID:
8836041
10.

Abnormal Paneth cell granule dissolution and compromised resistance to bacterial colonization in the intestine of CF mice.

Clarke LL, Gawenis LR, Bradford EM, Judd LM, Boyle KT, Simpson JE, Shull GE, Tanabe H, Ouellette AJ, Franklin CL, Walker NM.

Am J Physiol Gastrointest Liver Physiol. 2004 Jun;286(6):G1050-8. Epub 2004 Jan 8.

11.

A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells.

Huttner KM, Ouellette AJ.

Genomics. 1994 Nov 1;24(1):99-109.

PMID:
7896294
12.

Cryptdin gene expression in developing mouse small intestine.

Darmoul D, Brown D, Selsted ME, Ouellette AJ.

Am J Physiol. 1997 Jan;272(1 Pt 1):G197-206.

PMID:
9038894
13.

Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.

Ouellette AJ, Hsieh MM, Nosek MT, Cano-Gauci DF, Huttner KM, Buick RN, Selsted ME.

Infect Immun. 1994 Nov;62(11):5040-7.

14.

Peptide localization and gene structure of cryptdin 4, a differentially expressed mouse paneth cell alpha-defensin.

Ouellette AJ, Darmoul D, Tran D, Huttner KM, Yuan J, Selsted ME.

Infect Immun. 1999 Dec;67(12):6643-51.

15.

Alpha-defensins in the gastrointestinal tract.

Cunliffe RN.

Mol Immunol. 2003 Nov;40(7):463-7. Review.

PMID:
14568393
16.

Structure-activity determinants in paneth cell alpha-defensins: loss-of-function in mouse cryptdin-4 by charge-reversal at arginine residue positions.

Tanabe H, Qu X, Weeks CS, Cummings JE, Kolusheva S, Walsh KB, Jelinek R, Vanderlick TK, Selsted ME, Ouellette AJ.

J Biol Chem. 2004 Mar 19;279(12):11976-83. Epub 2003 Dec 31.

17.

Regulation of microbiota by antimicrobial peptides in the gut.

Masuda K, Nakamura K, Yoshioka S, Fukaya R, Sakai N, Ayabe T.

Adv Otorhinolaryngol. 2011;72:97-9. doi: 10.1159/000324625. Epub 2011 Aug 18. Review.

PMID:
21865701
18.

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense.

Wilson CL, Ouellette AJ, Satchell DP, Ayabe T, López-Boado YS, Stratman JL, Hultgren SJ, Matrisian LM, Parks WC.

Science. 1999 Oct 1;286(5437):113-7.

19.

Antimicrobial protection of the mouse testis: synthesis of defensins of the cryptdin family.

Grandjean V, Vincent S, Martin L, Rassoulzadegan M, Cuzin F.

Biol Reprod. 1997 Nov;57(5):1115-22.

PMID:
9369178
20.

Secreted enteric antimicrobial activity localises to the mucus surface layer.

Meyer-Hoffert U, Hornef MW, Henriques-Normark B, Axelsson LG, Midtvedt T, Pütsep K, Andersson M.

Gut. 2008 Jun;57(6):764-71. doi: 10.1136/gut.2007.141481. Epub 2008 Feb 4.

PMID:
18250125

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