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Items: 1 to 20 of 167

1.

Functional coexpression of HSV-1 thymidine kinase and green fluorescent protein: implications for noninvasive imaging of transgene expression.

Jacobs A, Dubrovin M, Hewett J, Sena-Esteves M, Tan CW, Slack M, Sadelain M, Breakefield XO, Tjuvajev JG.

Neoplasia. 1999 Jun;1(2):154-61.

2.

Positron emission tomography-based imaging of transgene expression mediated by replication-conditional, oncolytic herpes simplex virus type 1 mutant vectors in vivo.

Jacobs A, Tjuvajev JG, Dubrovin M, Akhurst T, Balatoni J, Beattie B, Joshi R, Finn R, Larson SM, Herrlinger U, Pechan PA, Chiocca EA, Breakefield XO, Blasberg RG.

Cancer Res. 2001 Apr 1;61(7):2983-95.

3.

Enhanced green fluorescent protein fusion proteins of herpes simplex virus type 1 thymidine kinase and cytochrome P450 4B1: applications for prodrug-activating gene therapy.

Steffens S, Frank S, Fischer U, Heuser C, Meyer KL, Dobberstein KU, Rainov NG, Kramm CM.

Cancer Gene Ther. 2000 May;7(5):806-12.

4.

Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography.

Tjuvajev JG, Avril N, Oku T, Sasajima T, Miyagawa T, Joshi R, Safer M, Beattie B, DiResta G, Daghighian F, Augensen F, Koutcher J, Zweit J, Humm J, Larson SM, Finn R, Blasberg R.

Cancer Res. 1998 Oct 1;58(19):4333-41.

5.

Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: a potential method for monitoring clinical gene therapy.

Tjuvajev JG, Finn R, Watanabe K, Joshi R, Oku T, Kennedy J, Beattie B, Koutcher J, Larson S, Blasberg RG.

Cancer Res. 1996 Sep 15;56(18):4087-95.

6.
7.

Herpes simplex virus thymidine kinase as a marker/reporter gene for PET imaging of gene therapy.

Blasberg RG, Tjuvajev JG.

Q J Nucl Med. 1999 Jun;43(2):163-9. Review.

PMID:
10429512
8.

Imaging expression of cytosine deaminase-herpes virus thymidine kinase fusion gene (CD/TK) expression with [124I]FIAU and PET.

Hackman T, Doubrovin M, Balatoni J, Beresten T, Ponomarev V, Beattie B, Finn R, Bornmann W, Blasberg R, Tjuvajev JG.

Mol Imaging. 2002 Jan-Mar;1(1):36-42.

9.

Improved herpes simplex virus type 1 amplicon vectors for proportional coexpression of positron emission tomography marker and therapeutic genes.

Jacobs AH, Winkeler A, Hartung M, Slack M, Dittmar C, Kummer C, Knoess C, Galldiks N, Vollmar S, Wienhard K, Heiss WD.

Hum Gene Ther. 2003 Feb 10;14(3):277-97.

PMID:
12639307
10.

Comparison of [18F]FHPG and [124/125I]FIAU for imaging herpes simplex virus type 1 thymidine kinase gene expression.

Brust P, Haubner R, Friedrich A, Scheunemann M, Anton M, Koufaki ON, Hauses M, Noll S, Noll B, Haberkorn U, Schackert G, Schackert HK, Avril N, Johannsen B.

Eur J Nucl Med. 2001 Jun;28(6):721-9.

PMID:
11440032
11.

Imaging TCR-dependent NFAT-mediated T-cell activation with positron emission tomography in vivo.

Ponomarev V, Doubrovin M, Lyddane C, Beresten T, Balatoni J, Bornman W, Finn R, Akhurst T, Larson S, Blasberg R, Sadelain M, Tjuvajev JG.

Neoplasia. 2001 Nov-Dec;3(6):480-8.

12.

A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging.

Ponomarev V, Doubrovin M, Serganova I, Vider J, Shavrin A, Beresten T, Ivanova A, Ageyeva L, Tourkova V, Balatoni J, Bornmann W, Blasberg R, Gelovani Tjuvajev J.

Eur J Nucl Med Mol Imaging. 2004 May;31(5):740-51. Epub 2004 Mar 11.

PMID:
15014901
13.

TK-GFP fusion gene virus vectors as tools for studying the features of HSV-TK/ganciclovir cancer gene therapy in vivo.

Pasanen T, Hakkarainen T, Timonen P, Parkkinen J, Tenhunen A, Loimas S, Wahlfors J.

Int J Mol Med. 2003 Oct;12(4):525-31.

PMID:
12964030
14.

In vitro and in vivo characterization of a dual-function green fluorescent protein--HSV1-thymidine kinase reporter gene driven by the human elongation factor 1 alpha promoter.

Luker GD, Luker KE, Sharma V, Pica CM, Dahlheimer JL, Ocheskey JA, Fahrner TJ, Milbrandt J, Piwnica-Worms D.

Mol Imaging. 2002 Apr-Jun;1(2):65-73.

15.

Generation of fusion genes carrying drug resistance, green fluorescent protein, and herpes simplex virus thymidine kinase genes in a single cistron.

Oh SC, Nam SY, Kwon HC, Kim CM, Seo JS, Seong RH, Jang YJ, Chung YH, Chung HY.

Mol Cells. 2001 Apr 30;11(2):192-7.

16.

PET of cardiac transgene expression: comparison of 2 approaches based on herpesviral thymidine kinase reporter gene.

Miyagawa M, Anton M, Haubner R, Simoes MV, Städele C, Erhardt W, Reder S, Lehner T, Wagner B, Noll S, Noll B, Grote M, Gambhir SS, Gansbacher B, Schwaiger M, Bengel FM.

J Nucl Med. 2004 Nov;45(11):1917-23.

17.

Quantitative kinetics of [124I]FIAU in cat and man.

Jacobs A, Bräunlich I, Graf R, Lercher M, Sakaki T, Voges J, Hesselmann V, Brandau W, Wienhard K, Heiss WD.

J Nucl Med. 2001 Mar;42(3):467-75.

18.

Construction of mutant TKGFP for real-time imaging of temporal dynamics of HIF-1 signal transduction activity mediated by hypoxia and reoxygenation in tumors in living mice.

Hsieh CH, Kuo JW, Lee YJ, Chang CW, Gelovani JG, Liu RS.

J Nucl Med. 2009 Dec;50(12):2049-57. doi: 10.2967/jnumed.108.061234. Epub 2009 Nov 12.

19.
20.

Imaging of gene expression in live pancreatic islet cell lines using dual-isotope SPECT.

Tai JH, Nguyen B, Wells RG, Kovacs MS, McGirr R, Prato FS, Morgan TG, Dhanvantari S.

J Nucl Med. 2008 Jan;49(1):94-102. Epub 2007 Dec 12.

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