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Items: 1 to 20 of 229

1.

Anti-tumor activity of K1-LysPE38QQR, an immunotoxin targeting mesothelin, a cell-surface antigen overexpressed in ovarian cancer and malignant mesothelioma.

Hassan R, Viner JL, Wang QC, Margulies I, Kreitman RJ, Pastan I.

J Immunother. 2000 Jul-Aug;23(4):473-9.

PMID:
10916757
2.

Bivalent disulfide-stabilized fragment variable immunotoxin directed against mesotheliomas and ovarian cancer.

Bera TK, Williams-Gould J, Beers R, Chowdhury P, Pastan I.

Mol Cancer Ther. 2001 Dec;1(2):79-84.

3.
4.

Antitumor effects of B3-PE and B3-LysPE40 in a nude mouse model of human breast cancer and the evaluation of B3-PE toxicity in monkeys.

Pai LH, Batra JK, FitzGerald DJ, Willingham MC, Pastan I.

Cancer Res. 1992 Jun 1;52(11):3189-93.

7.

Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin.

Batra JK, Jinno Y, Chaudhary VK, Kondo T, Willingham MC, FitzGerald DJ, Pastan I.

Proc Natl Acad Sci U S A. 1989 Nov;86(21):8545-9.

8.

Enhanced therapeutic efficacy against an ovarian tumor xenograft of immunotoxins used in conjunction with recombinant alpha-interferon.

Pearson JW, Hedrick E, Fogler WE, Bull RL, Ferris DK, Riggs CW, Wiltrout RH, Sivam G, Morgan AC, Groves E, et al.

Cancer Res. 1990 Oct 1;50(19):6379-88.

10.

Improved binding and antitumor activity of a recombinant anti-erbB2 immunotoxin by disulfide stabilization of the Fv fragment.

Reiter Y, Brinkmann U, Jung SH, Lee B, Kasprzyk PG, King CR, Pastan I.

J Biol Chem. 1994 Jul 15;269(28):18327-31.

11.

Anti-tumor activities of immunotoxins made of monoclonal antibody B3 and various forms of Pseudomonas exotoxin.

Pai LH, Batra JK, FitzGerald DJ, Willingham MC, Pastan I.

Proc Natl Acad Sci U S A. 1991 Apr 15;88(8):3358-62. Erratum in: Proc Natl Acad Sci U S A 1991 Jun 1;88(11):5066.

12.

Targeted therapy against human lung cancer in nude mice by high-affinity recombinant antimesothelin single-chain Fv immunotoxin.

Fan D, Yano S, Shinohara H, Solorzano C, Van Arsdall M, Bucana CD, Pathak S, Kruzel E, Herbst RS, Onn A, Roach JS, Onda M, Wang QC, Pastan I, Fidler IJ.

Mol Cancer Ther. 2002 Jun;1(8):595-600.

14.
15.

Pseudomonas exotoxin-based immunotoxins containing the antibody LL2 or LL2-Fab' induce regression of subcutaneous human B-cell lymphoma in mice.

Kreitman RJ, Hansen HJ, Jones AL, FitzGerald DJ, Goldenberg DM, Pastan I.

Cancer Res. 1993 Feb 15;53(4):819-25.

16.

Antitumor effects of an immunotoxin made with Pseudomonas exotoxin in a nude mouse model of human ovarian cancer.

FitzGerald DJ, Willingham MC, Pastan I.

Proc Natl Acad Sci U S A. 1986 Sep;83(17):6627-30.

17.

Characterization of immunotoxins active against ovarian cancer cell lines.

Pirker R, FitzGerald DJ, Hamilton TC, Ozols RF, Laird W, Frankel AE, Willingham MC, Pastan I.

J Clin Invest. 1985 Sep;76(3):1261-7.

18.
19.

B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice.

Brinkmann U, Pai LH, FitzGerald DJ, Willingham M, Pastan I.

Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8616-20.

20.

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