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Items: 1 to 20 of 320

1.

A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits.

Okamoto H, Yonemori F, Wakitani K, Minowa T, Maeda K, Shinkai H.

Nature. 2000 Jul 13;406(6792):203-7.

PMID:
10910363
2.

Pharmacological modulation of cholesteryl ester transfer protein, a new therapeutic target in atherogenic dyslipidemia.

Le Goff W, Guerin M, Chapman MJ.

Pharmacol Ther. 2004 Jan;101(1):17-38. Review.

PMID:
14729390
3.

Cholesteryl ester transfer protein inhibitor (JTT-705) and the development of atherosclerosis in rabbits with severe hypercholesterolaemia.

Huang Z, Inazu A, Nohara A, Higashikata T, Mabuchi H.

Clin Sci (Lond). 2002 Dec;103(6):587-94.

PMID:
12444911
4.

Effect of inhibiting cholesteryl ester transfer protein on the kinetics of high-density lipoprotein cholesteryl ester transport in plasma: in vivo studies in rabbits.

Kee P, Caiazza D, Rye KA, Barrett PH, Morehouse LA, Barter PJ.

Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):884-90.

5.

Cholesteryl ester transfer protein: an enigmatic protein.

Moulin P.

Horm Res. 1996;45(3-5):238-44. Review.

PMID:
8964591
6.

Effect of JTT-705 on cholesteryl ester transfer protein and plasma lipid levels in normolipidemic animals.

Okamoto H, Iwamoto Y, Maki M, Sotani T, Yonemori F, Wakitani K.

Eur J Pharmacol. 2003 Apr 11;466(1-2):147-54.

PMID:
12679151
7.

Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice.

Föger B, Chase M, Amar MJ, Vaisman BL, Shamburek RD, Paigen B, Fruchart-Najib J, Paiz JA, Koch CA, Hoyt RF, Brewer HB Jr, Santamarina-Fojo S.

J Biol Chem. 1999 Dec 24;274(52):36912-20.

8.

Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein.

Marotti KR, Castle CK, Boyle TP, Lin AH, Murray RW, Melchior GW.

Nature. 1993 Jul 1;364(6432):73-5.

PMID:
8316302
9.

Effect of antisense oligonucleotides against cholesteryl ester transfer protein on the development of atherosclerosis in cholesterol-fed rabbits.

Sugano M, Makino N, Sawada S, Otsuka S, Watanabe M, Okamoto H, Kamada M, Mizushima A.

J Biol Chem. 1998 Feb 27;273(9):5033-6.

11.

Cholesteryl ester transfer protein inhibition, high-density lipoprotein metabolism and heart disease risk reduction.

Schaefer EJ, Asztalos BF.

Curr Opin Lipidol. 2006 Aug;17(4):394-8. Review.

PMID:
16832162
12.

Cholesteryl ester transfer protein: a novel target for raising HDL and inhibiting atherosclerosis.

Barter PJ, Brewer HB Jr, Chapman MJ, Hennekens CH, Rader DJ, Tall AR.

Arterioscler Thromb Vasc Biol. 2003 Feb 1;23(2):160-7. Review.

13.
14.

Efficacy and safety of a novel cholesteryl ester transfer protein inhibitor, JTT-705, in humans: a randomized phase II dose-response study.

de Grooth GJ, Kuivenhoven JA, Stalenhoef AF, de Graaf J, Zwinderman AH, Posma JL, van Tol A, Kastelein JJ.

Circulation. 2002 May 7;105(18):2159-65.

15.

Increased high-density lipoprotein cholesterol concentration in alcoholics is related to low cholesteryl ester transfer protein activity.

Savolainen MJ, Hannuksela M, Seppänen S, Kervinen K, Kesäniemi YA.

Eur J Clin Invest. 1990 Dec;20(6):593-9.

PMID:
2127749
16.

Cholesteryl ester transfer protein (CETP) inhibition beyond raising high-density lipoprotein cholesterol levels: pathways by which modulation of CETP activity may alter atherogenesis.

Klerkx AH, El Harchaoui K, van der Steeg WA, Boekholdt SM, Stroes ES, Kastelein JJ, Kuivenhoven JA.

Arterioscler Thromb Vasc Biol. 2006 Apr;26(4):706-15. Review.

17.

Targeting cholesteryl ester transfer protein for the prevention and management of cardiovascular disease.

Barter PJ, Kastelein JJ.

J Am Coll Cardiol. 2006 Feb 7;47(3):492-9. Review.

19.

Stereospecific inhibition of CETP by chiral N,N-disubstituted trifluoro-3-amino-2-propanols.

Connolly DT, Witherbee BJ, Melton MA, Durley RC, Grapperhaus ML, McKinnis BR, Vernier WF, Babler MA, Shieh JJ, Smith ME, Sikorski JA.

Biochemistry. 2000 Nov 14;39(45):13870-9.

PMID:
11076528
20.
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