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Items: 1 to 20 of 48

1.

Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.

Klapper LN, Waterman H, Sela M, Yarden Y.

Cancer Res. 2000 Jul 1;60(13):3384-8.

2.

A subclass of tumor-inhibitory monoclonal antibodies to ErbB-2/HER2 blocks crosstalk with growth factor receptors.

Klapper LN, Vaisman N, Hurwitz E, Pinkas-Kramarski R, Yarden Y, Sela M.

Oncogene. 1997 May 1;14(17):2099-109.

3.

Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors.

Haglund K, Shimokawa N, Szymkiewicz I, Dikic I.

Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12191-6.

4.

In vitro and in vivo anti-tumour effects of a humanised monoclonal antibody against c-erbB-2 product.

Tokuda Y, Ohnishi Y, Shimamura K, Iwasawa M, Yoshimura M, Ueyama Y, Tamaoki N, Tajima T, Mitomi T.

Br J Cancer. 1996 Jun;73(11):1362-5.

5.

C-erbB-2/ HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines.

Grothey A, Hashizume R, Ji H, Tubb BE, Patrick CW Jr, Yu D, Mooney EE, McCrea PD.

Oncogene. 2000 Oct 5;19(42):4864-75.

6.

Specific inhibition of the reaction between a tumor-inhibitory antibody and the ErbB-2 receptor by a mimotope derived from a phage display library.

Vaisman N, Nissim A, Klapper LN, Tirosh B, Yarden Y, Sela M.

Immunol Lett. 2000 Dec 1;75(1):61-7.

PMID:
11163868
7.

Cbl-ArgBP2 complex mediates ubiquitination and degradation of c-Abl.

Soubeyran P, Barac A, Szymkiewicz I, Dikic I.

Biochem J. 2003 Feb 15;370(Pt 1):29-34.

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10.

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor.

Levkowitz G, Waterman H, Zamir E, Kam Z, Oved S, Langdon WY, Beguinot L, Geiger B, Yarden Y.

Genes Dev. 1998 Dec 1;12(23):3663-74.

11.

Construction, expression and characterization of the engineered antibody against tumor surface antigen, p185(c-erbB-2).

Cheng LS, Liu AP, Yang JH, Dong YQ, Li LW, Wang J, Wang CC, Liu J.

Cell Res. 2003 Feb;13(1):35-48.

12.

Prolonged survival of mice with human gastric cancer treated with an anti-c-ErbB-2 monoclonal antibody.

Ohnishi Y, Nakamura H, Yoshimura M, Tokuda Y, Iwasawa M, Ueyama Y, Tamaoki N, Shimamura K.

Br J Cancer. 1995 May;71(5):969-73.

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Epidermal growth factor contains both positive and negative determinants for interaction with ErbB-2/ErbB-3 heterodimers.

Stortelers C, van De Poll ML, Lenferink AE, Gadellaa MM, van Zoelen C, van Zoelen EJ.

Biochemistry. 2002 Apr 2;41(13):4292-301.

PMID:
11914075
20.
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