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Items: 1 to 20 of 124


Neoplastic transformation by Notch requires nuclear localization.

Jeffries S, Capobianco AJ.

Mol Cell Biol. 2000 Jun;20(11):3928-41.


Neoplastic transformation by Notch is independent of transcriptional activation by RBP-J signalling.

Dumont E, Fuchs KP, Bommer G, Christoph B, Kremmer E, Kempkes B.

Oncogene. 2000 Jan 27;19(4):556-61.


Activated Notch1 modulates gene expression in B cells similarly to Epstein-Barr viral nuclear antigen 2.

Strobl LJ, Höfelmayr H, Marschall G, Brielmeier M, Bornkamm GW, Zimber-Strobl U.

J Virol. 2000 Feb;74(4):1727-35.


The origin of the ankyrin repeat region in Notch intracellular domains is critical for regulation of HES promoter activity.

Beatus P, Lundkvist J, Oberg C, Pedersen K, Lendahl U.

Mech Dev. 2001 Jun;104(1-2):3-20.


Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling.

Berezovska O, Jack C, McLean P, Aster JC, Hicks C, Xia W, Wolfe MS, Kimberly WT, Weinmaster G, Selkoe DJ, Hyman BT.

J Neurochem. 2000 Aug;75(2):583-93.


Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain.

Wang J, Shelly L, Miele L, Boykins R, Norcross MA, Guan E.

J Immunol. 2001 Jul 1;167(1):289-95.


Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis.

Kuroda K, Tani S, Tamura K, Minoguchi S, Kurooka H, Honjo T.

J Biol Chem. 1999 Mar 12;274(11):7238-44.


HERP, a new primary target of Notch regulated by ligand binding.

Iso T, Sartorelli V, Chung G, Shichinohe T, Kedes L, Hamamori Y.

Mol Cell Biol. 2001 Sep;21(17):6071-9.


Repression of activator protein-1-mediated transcriptional activation by the Notch-1 intracellular domain.

Chu J, Jeffries S, Norton JE, Capobianco AJ, Bresnick EH.

J Biol Chem. 2002 Mar 1;277(9):7587-97. Epub 2001 Dec 5.


Effect of PS1 deficiency and an APP gamma-secretase inhibitor on Notch1 signaling in primary mammalian neurons.

Jack C, Berezovska O, Wolfe MS, Hyman BT.

Brain Res Mol Brain Res. 2001 Mar 5;87(2):166-74.


p300 acts as a transcriptional coactivator for mammalian Notch-1.

Oswald F, Täuber B, Dobner T, Bourteele S, Kostezka U, Adler G, Liptay S, Schmid RM.

Mol Cell Biol. 2001 Nov;21(22):7761-74.


HERP1 is a cell type-specific primary target of Notch.

Iso T, Chung G, Hamamori Y, Kedes L.

J Biol Chem. 2002 Feb 22;277(8):6598-607. Epub 2001 Dec 6.


Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex.

Nam Y, Weng AP, Aster JC, Blacklow SC.

J Biol Chem. 2003 Jun 6;278(23):21232-9. Epub 2003 Mar 18.


Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2.

Hsieh JJ, Henkel T, Salmon P, Robey E, Peterson MG, Hayward SD.

Mol Cell Biol. 1996 Mar;16(3):952-9.

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