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Items: 1 to 20 of 709

1.

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions.

Graser RT, DiLorenzo TP, Wang F, Christianson GJ, Chapman HD, Roopenian DC, Nathenson SG, Serreze DV.

J Immunol. 2000 Apr 1;164(7):3913-8.

2.
3.

Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice.

Verdaguer J, Schmidt D, Amrani A, Anderson B, Averill N, Santamaria P.

J Exp Med. 1997 Nov 17;186(10):1663-76.

4.

MHC class II molecules play a role in the selection of autoreactive class I-restricted CD8 T cells that are essential contributors to type 1 diabetes development in nonobese diabetic mice.

Serreze DV, Holl TM, Marron MP, Graser RT, Johnson EA, Choisy-Rossi C, Slattery RM, Lieberman SM, DiLorenzo TP.

J Immunol. 2004 Jan 15;172(2):871-9.

5.

Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4.

Takaki T, Lieberman SM, Holl TM, Han B, Santamaria P, Serreze DV, DiLorenzo TP.

J Immunol. 2004 Aug 15;173(4):2530-41.

7.

Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains.

Verdaguer J, Yoon JW, Anderson B, Averill N, Utsugi T, Park BJ, Santamaria P.

J Immunol. 1996 Nov 15;157(10):4726-35.

PMID:
8906855
8.

Through regulation of TCR expression levels, an Idd7 region gene(s) interactively contributes to the impaired thymic deletion of autoreactive diabetogenic CD8+ T cells in nonobese diabetic mice.

Serreze DV, Choisy-Rossi CM, Grier AE, Holl TM, Chapman HD, Gahagan JR, Osborne MA, Zhang W, King BL, Brown A, Roopenian D, Marron MP.

J Immunol. 2008 Mar 1;180(5):3250-9.

9.

Active CD4+ helper T cells directly stimulate CD8+ cytotoxic T lymphocyte responses in wild-type and MHC II gene knockout C57BL/6 mice and transgenic RIP-mOVA mice expressing islet beta-cell ovalbumin antigen leading to diabetes.

Ye Z, Ahmed KA, Hao S, Zhang X, Xie Y, Munegowda MA, Meng Q, Chibbar R, Xiang J.

Autoimmunity. 2008 Nov;41(7):501-11. doi: 10.1080/08916930802069256.

PMID:
18855194
10.

Cross-priming of diabetogenic T cells dissociated from CTL-induced shedding of beta cell autoantigens.

Yamanouchi J, Verdaguer J, Han B, Amrani A, Serra P, Santamaria P.

J Immunol. 2003 Dec 15;171(12):6900-9.

11.

HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes.

Takaki T, Marron MP, Mathews CE, Guttmann ST, Bottino R, Trucco M, DiLorenzo TP, Serreze DV.

J Immunol. 2006 Mar 1;176(5):3257-65.

12.

Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.

Serreze DV, Johnson EA, Chapman HD, Graser RT, Marron MP, DiLorenzo TP, Silveira P, Yoshimura Y, Nathenson SG, Joyce S.

Diabetes. 2001 Sep;50(9):1992-2000.

13.
14.

Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent.

Serreze DV, Chapman HD, Varnum DS, Gerling I, Leiter EH, Shultz LD.

J Immunol. 1997 Apr 15;158(8):3978-86.

PMID:
9103469
15.

Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.

Anderson B, Park BJ, Verdaguer J, Amrani A, Santamaria P.

Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9311-6.

16.

Beta-cell-cytotoxic CD8+ T cells from nonobese diabetic mice use highly homologous T cell receptor alpha-chain CDR3 sequences.

Santamaria P, Utsugi T, Park BJ, Averill N, Kawazu S, Yoon JW.

J Immunol. 1995 Mar 1;154(5):2494-503.

PMID:
7868915
17.

Enhanced pathogenicity of diabetogenic T cells escaping a non-MHC gene-controlled near death experience.

Choisy-Rossi CM, Holl TM, Pierce MA, Chapman HD, Serreze DV.

J Immunol. 2004 Sep 15;173(6):3791-800.

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20.

CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice.

Pang S, Zhang L, Wang H, Yi Z, Li L, Gao L, Zhao J, Tisch R, Katz JD, Wang B.

Eur J Immunol. 2009 Oct;39(10):2716-24. doi: 10.1002/eji.200939408.

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