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Items: 1 to 20 of 88

1.

The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling properties.

Qian X, Esteban L, Vass WC, Upadhyaya C, Papageorge AG, Yienger K, Ward JM, Lowy DR, Santos E.

EMBO J. 2000 Feb 15;19(4):642-54.

2.
3.

Activation of Ras-dependent signaling pathways by G(14) -coupled receptors requires the adaptor protein TPR1.

Kwan DH, Yung LY, Ye RD, Wong YH.

J Cell Biochem. 2012 Nov;113(11):3486-97. doi: 10.1002/jcb.24225.

PMID:
22711498
4.

Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival.

Baltanás FC, Pérez-Andrés M, Ginel-Picardo A, Diaz D, Jimeno D, Liceras-Boillos P, Kortum RL, Samelson LE, Orfao A, Santos E.

Mol Cell Biol. 2013 Nov;33(22):4562-78. doi: 10.1128/MCB.01026-13.

5.

Ras-guanine nucleotide exchange factor sos2 is dispensable for mouse growth and development.

Esteban LM, Fernández-Medarde A, López E, Yienger K, Guerrero C, Ward JM, Tessarollo L, Santos E.

Mol Cell Biol. 2000 Sep;20(17):6410-3.

7.

Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development.

Wang DZ, Hammond VE, Abud HE, Bertoncello I, McAvoy JW, Bowtell DD.

Genes Dev. 1997 Feb 1;11(3):309-20.

8.

Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1.

Reynolds LF, de Bettignies C, Norton T, Beeser A, Chernoff J, Tybulewicz VL.

J Biol Chem. 2004 Apr 30;279(18):18239-46.

10.

A novel SOS1 mutation in Costello/CFC syndrome affects signaling in both RAS and PI3K pathways.

Tumurkhuu M, Saitoh M, Takita J, Mizuno Y, Mizuguchi M.

J Recept Signal Transduct Res. 2013 Apr;33(2):124-8. doi: 10.3109/10799893.2013.779279.

PMID:
23528009
13.

Deconstructing Ras signaling in the thymus.

Kortum RL, Sommers CL, Pinski JM, Alexander CP, Merrill RK, Li W, Love PE, Samelson LE.

Mol Cell Biol. 2012 Jul;32(14):2748-59. doi: 10.1128/MCB.00317-12.

14.

Sos1 regulates sustained TCR-mediated Erk activation.

Poltorak M, Meinert I, Stone JC, Schraven B, Simeoni L.

Eur J Immunol. 2014 May;44(5):1535-40. doi: 10.1002/eji.201344046.

15.

SUMOylation of Grb2 enhances the ERK activity by increasing its binding with Sos1.

Qu Y, Chen Q, Lai X, Zhu C, Chen C, Zhao X, Deng R, Xu M, Yuan H, Wang Y, Yu J, Huang J.

Mol Cancer. 2014 Apr 29;13:95. doi: 10.1186/1476-4598-13-95.

16.

Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos.

Zhao C, Du G, Skowronek K, Frohman MA, Bar-Sagi D.

Nat Cell Biol. 2007 Jun;9(6):706-12.

PMID:
17486115
17.

SOS1 over-expression in genital skin fibroblasts from hirsute women: a putative role of the SOS1/RAS pathway in the pathogenesis of hirsutism.

Minella D, Wannenes F, Biancolella M, Amati F, Testa B, Nardone A, Bueno S, Fabbri A, Lauro D, Novelli G, Moretti C.

J Biol Regul Homeost Agents. 2011 Oct-Dec;25(4):615-26.

PMID:
22217993
18.

Understanding SOS (Son of Sevenless).

Pierre S, Bats AS, Coumoul X.

Biochem Pharmacol. 2011 Nov 1;82(9):1049-56. doi: 10.1016/j.bcp.2011.07.072. Review.

PMID:
21787760
19.
20.

Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L.

Wang JB, Wu WJ, Cerione RA.

J Biol Chem. 2005 Jun 17;280(24):22883-91.

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