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Items: 1 to 20 of 98


Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1).

Chen YR, Meyer CF, Ahmed B, Yao Z, Tan TH.

Oncogene. 1999 Dec 2;18(51):7370-7.


Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB.

Arnold R, Liou J, Drexler HC, Weiss A, Kiefer F.

J Biol Chem. 2001 May 4;276(18):14675-84. Epub 2001 Jan 29.


A novel src homology 3 domain-containing adaptor protein, HIP-55, that interacts with hematopoietic progenitor kinase 1.

Ensenat D, Yao Z, Wang XS, Kori R, Zhou G, Lee SC, Tan TH.

J Biol Chem. 1999 Nov 26;274(48):33945-50. Erratum in: J Biol Chem 2000 May 5;275(18):14004.


Sustained JNK signaling by proteolytically processed HPK1 mediates IL-3 independent survival during monocytic differentiation.

Arnold R, Frey CR, Müller W, Brenner D, Krammer PH, Kiefer F.

Cell Death Differ. 2007 Mar;14(3):568-75. Epub 2006 Oct 6.


Functional interactions of HPK1 with adaptor proteins.

Boomer JS, Tan TH.

J Cell Biochem. 2005 May 1;95(1):34-44. Review.


Enhanced JNK activation by NESK without kinase activity upon caspase-mediated cleavage during apoptosis.

Kakinuma H, Inomata H, Kitamura N.

Cell Signal. 2005 Nov;17(11):1439-48.


The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins.

Oehrl W, Kardinal C, Ruf S, Adermann K, Groffen J, Feng GS, Blenis J, Tan TH, Feller SM.

Oncogene. 1998 Oct 15;17(15):1893-901.


Hematopoietic progenitor kinase 1 supports apoptosis of T lymphocytes.

Schulze-Luehrmann J, Santner-Nanan B, Jha MK, Schimpl A, Avots A, Serfling E.

Blood. 2002 Aug 1;100(3):954-60.


Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress.

Ito Y, Pandey P, Sathyanarayana P, Ling P, Rana A, Weichselbaum R, Tan TH, Kufe D, Kharbanda S.

J Biol Chem. 2001 May 25;276(21):18130-8. Epub 2001 Jan 30.


Proteolytic activation of PKN by caspase-3 or related protease during apoptosis.

Takahashi M, Mukai H, Toshimori M, Miyamoto M, Ono Y.

Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11566-71.


MST1-JNK promotes apoptosis via caspase-dependent and independent pathways.

Ura S, Masuyama N, Graves JD, Gotoh Y.

Genes Cells. 2001 Jun;6(6):519-30.


MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation.

Lee KK, Ohyama T, Yajima N, Tsubuki S, Yonehara S.

J Biol Chem. 2001 Jun 1;276(22):19276-85. Epub 2001 Mar 7.


Caspase-cleaved HPK1 induces CD95L-independent activation-induced cell death in T and B lymphocytes.

Brenner D, Golks A, Becker M, Müller W, Frey CR, Novak R, Melamed D, Kiefer F, Krammer PH, Arnold R.

Blood. 2007 Dec 1;110(12):3968-77. Epub 2007 Aug 21.


Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway.

Sawasdikosol S, Pyarajan S, Alzabin S, Matejovic G, Burakoff SJ.

J Biol Chem. 2007 Nov 30;282(48):34693-9. Epub 2007 Sep 25.


Specific proteolysis of the A-kinase-anchoring protein 149 at the Asp582 residue by caspases during apoptosis.

Yoo H, Cha HJ, Lee J, Yu EO, Bae S, Jung JH, Sohn I, Lee SJ, Yang KH, Woo SH, Seo SK, Park IC, Kim CS, Jin YW, Ahn SK.

Oncol Rep. 2008 Jun;19(6):1577-82.

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