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Items: 1 to 20 of 100

1.
2.

Biochemistry and pharmacology of catechol-O-methyltransferase inhibitors.

Nissinen E, Männistö PT.

Int Rev Neurobiol. 2010;95:73-118. doi: 10.1016/B978-0-12-381326-8.00005-3. Review.

PMID:
21095460
3.
4.

Catechol-O-methyltransferase and Parkinson's disease.

Tai CH, Wu RM.

Acta Med Okayama. 2002 Feb;56(1):1-6. Review.

5.

Catechol-O-methyltransferase and its inhibitors in Parkinson's disease.

Bonifácio MJ, Palma PN, Almeida L, Soares-da-Silva P.

CNS Drug Rev. 2007 Fall;13(3):352-79. Review.

6.

Characteristics of catechol O-methyl-transferase (COMT) and properties of selective COMT inhibitors.

Männistö PT, Ulmanen I, Lundström K, Taskinen J, Tenhunen J, Tilgmann C, Kaakkola S.

Prog Drug Res. 1992;39:291-350. Review. No abstract available.

PMID:
1475365
7.

Regulation of catechol O-methyltransferase expression in granulosa cells: a potential role for follicular arrest in polycystic ovary syndrome.

Salih SM, Jamaluddin M, Salama SA, Fadl AA, Nagamani M, Al-Hendy A.

Fertil Steril. 2008 May;89(5 Suppl):1414-21.

PMID:
17612537
8.

Bisubstrate inhibitors for the enzyme catechol-O-methyltransferase (COMT): influence of inhibitor preorganisation and linker length between the two substrate moieties on binding affinity.

Lerner C, Masjost B, Ruf A, Gramlich V, Jakob-Roetne R, Zürcher G, Borroni E, Diederich F.

Org Biomol Chem. 2003 Jan 7;1(1):42-9.

PMID:
12929389
9.

A semiempirical study on inhibition of catechol O-methyltransferase by substituted catechols.

Ovaska M, Yliniemelä A.

J Comput Aided Mol Des. 1998 May;12(3):301-7.

PMID:
9749372
10.

Comparative study of ortho- and meta-nitrated inhibitors of catechol-O-methyltransferase: interactions with the active site and regioselectivity of O-methylation.

Palma PN, Rodrigues ML, Archer M, Bonifácio MJ, Loureiro AI, Learmonth DA, Carrondo MA, Soares-da-Silva P.

Mol Pharmacol. 2006 Jul;70(1):143-53.

11.

Bisubstrate inhibitors of the enzyme catechol O-methyltransferase (COMT): efficient inhibition despite the lack of a nitro group.

Paulini R, Lerner C, Jakob-Roetne R, Zürcher G, Borroni E, Diederich F.

Chembiochem. 2004 Sep 6;5(9):1270-4. No abstract available.

PMID:
15368579
12.

Molecular modeling and metabolic studies of the interaction of catechol-O-methyltransferase and a new nitrocatechol inhibitor.

Palma PN, Bonifácio MJ, Loureiro AI, Wright LC, Learmonth DA, Soares-da-Silva P.

Drug Metab Dispos. 2003 Mar;31(3):250-8.

13.

Microplate screening assay to identify inhibitors of human catechol-O-methyltransferase.

Kurkela M, Siiskonen A, Finel M, Tammela P, Taskinen J, Vuorela P.

Anal Biochem. 2004 Aug 1;331(1):198-200. No abstract available.

PMID:
15246016
14.

Structure-based design, synthesis, and in vitro evaluation of bisubstrate inhibitors for catechol O-methyltransferase (COMT).

Masjost B, Ballmer P, Borroni E, Zürcher G, Winkler FK, Jakob-Roetne R, Diederich F.

Chemistry. 2000 Mar 17;6(6):971-82.

PMID:
10785817
15.

Molecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitors.

Ellermann M, Paulini R, Jakob-Roetne R, Lerner C, Borroni E, Roth D, Ehler A, Schweizer WB, Schlatter D, Rudolph MG, Diederich F.

Chemistry. 2011 May 27;17(23):6369-81. doi: 10.1002/chem.201003648.

PMID:
21538606
16.

Crystal structures of rat catechol-O-methyltransferase complexed with coumarine-based inhibitor.

Tsuji E, Okazaki K, Takeda K.

Biochem Biophys Res Commun. 2009 Jan 16;378(3):494-7. doi: 10.1016/j.bbrc.2008.11.085.

PMID:
19056347
17.

Synthesis of 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenyl-ethanone and derivatives as potent and long-acting peripheral inhibitors of catechol-O-methyltransferase.

Learmonth DA, Vieira-Coelho MA, Benes J, Alves PC, Borges N, Freitas AP, da-Silva PS.

J Med Chem. 2002 Jan 31;45(3):685-95.

PMID:
11806720
18.

Exclusion of the catechol-o-methyltransferase gene from genes contributing to salt-sensitive hypertension in dahl salt-sensitive rats.

Kajimoto K, Hiura Y, Sumiya T, Yasui N, Okuda T, Iwai N.

Hypertens Res. 2007 May;30(5):459-67.

PMID:
17587758
20.

Molecular modelling study of the mechanism of high-potency inhibition of human catechol-O-methyltransferase by (-)-epigallocatechin-3-O-gallate.

Zhu BT, Shim JY, Nagai M, Bai HW.

Xenobiotica. 2008 Feb;38(2):130-46. doi: 10.1080/00498250701744641 .

PMID:
18197555

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