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Items: 1 to 20 of 199

1.

Ras and Rap1: two highly related small GTPases with distinct function.

Zwartkruis FJ, Bos JL.

Exp Cell Res. 1999 Nov 25;253(1):157-65. Review.

PMID:
10579920
2.
3.

The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytes.

Yoshikawa Y, Satoh T, Tamura T, Wei P, Bilasy SE, Edamatsu H, Aiba A, Katagiri K, Kinashi T, Nakao K, Kataoka T.

Mol Biol Cell. 2007 Aug;18(8):2949-59. Epub 2007 May 30.

4.
5.

CalDAG-GEFIII activation of Ras, R-ras, and Rap1.

Yamashita S, Mochizuki N, Ohba Y, Tobiume M, Okada Y, Sawa H, Nagashima K, Matsuda M.

J Biol Chem. 2000 Aug 18;275(33):25488-93.

6.

Crk activation of JNK via C3G and R-Ras.

Mochizuki N, Ohba Y, Kobayashi S, Otsuka N, Graybiel AM, Tanaka S, Matsuda M.

J Biol Chem. 2000 Apr 28;275(17):12667-71.

7.

The role of Rap1 in integrin-mediated cell adhesion.

Bos JL, de Bruyn K, Enserink J, Kuiperij B, Rangarajan S, Rehmann H, Riedl J, de Rooij J, van Mansfeld F, Zwartkruis F.

Biochem Soc Trans. 2003 Feb;31(Pt 1):83-6. Review.

PMID:
12546659
8.

Rap1, a mercenary among the Ras-like GTPases.

Frische EW, Zwartkruis FJ.

Dev Biol. 2010 Apr 1;340(1):1-9. doi: 10.1016/j.ydbio.2009.12.043. Epub 2010 Jan 7. Review.

9.

A growing family of guanine nucleotide exchange factors is responsible for activation of Ras-family GTPases.

Quilliam LA, Rebhun JF, Castro AF.

Prog Nucleic Acid Res Mol Biol. 2002;71:391-444. Review.

PMID:
12102558
10.

PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2.

de Rooij J, Boenink NM, van Triest M, Cool RH, Wittinghofer A, Bos JL.

J Biol Chem. 1999 Dec 31;274(53):38125-30.

11.

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

Enserink JM, Christensen AE, de Rooij J, van Triest M, Schwede F, Genieser HG, Døskeland SO, Blank JL, Bos JL.

Nat Cell Biol. 2002 Nov;4(11):901-6.

PMID:
12402047
12.

Rap1 GTPase: functions, regulation, and malignancy.

Hattori M, Minato N.

J Biochem. 2003 Oct;134(4):479-84. Review.

13.

Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor.

Rangarajan S, Enserink JM, Kuiperij HB, de Rooij J, Price LS, Schwede F, Bos JL.

J Cell Biol. 2003 Feb 17;160(4):487-93. Epub 2003 Feb 10.

14.

Nitric oxide activates Rap1 and Ral in a Ras-independent manner.

Mittar D, Sehajpal PK, Lander HM.

Biochem Biophys Res Commun. 2004 Sep 10;322(1):203-9.

PMID:
15313192
15.
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17.

p130Cas regulates the activity of AND-34, a novel Ral, Rap1, and R-Ras guanine nucleotide exchange factor.

Gotoh T, Cai D, Tian X, Feig LA, Lerner A.

J Biol Chem. 2000 Sep 29;275(39):30118-23.

18.

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling.

Zwartkruis FJ, Wolthuis RM, Nabben NM, Franke B, Bos JL.

EMBO J. 1998 Oct 15;17(20):5905-12.

19.

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP.

de Rooij J, Zwartkruis FJ, Verheijen MH, Cool RH, Nijman SM, Wittinghofer A, Bos JL.

Nature. 1998 Dec 3;396(6710):474-7.

PMID:
9853756
20.

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