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Items: 1 to 20 of 88

1.

p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB.

Bachelder RE, Ribick MJ, Marchetti A, Falcioni R, Soddu S, Davis KR, Mercurio AM.

J Cell Biol. 1999 Nov 29;147(5):1063-72.

2.

Activation of p53 function in carcinoma cells by the alpha6beta4 integrin.

Bachelder RE, Marchetti A, Falcioni R, Soddu S, Mercurio AM.

J Biol Chem. 1999 Jul 16;274(29):20733-7.

3.
4.

Integrin-linked kinase (ILK): a "hot" therapeutic target.

Yoganathan TN, Costello P, Chen X, Jabali M, Yan J, Leung D, Zhang Z, Yee A, Dedhar S, Sanghera J.

Biochem Pharmacol. 2000 Oct 15;60(8):1115-9. Review.

PMID:
11007949
5.

Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1).

Wrede CE, Dickson LM, Lingohr MK, Briaud I, Rhodes CJ.

J Biol Chem. 2002 Dec 20;277(51):49676-84. Epub 2002 Oct 21.

6.

Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways.

Akimoto T, Nonaka T, Ishikawa H, Sakurai H, Saitoh JI, Takahashi T, Mitsuhashi N.

Int J Radiat Oncol Biol Phys. 2001 May 1;50(1):195-201.

PMID:
11316564
7.

Oncogenic transformation of cells by a conditionally active form of the protein kinase Akt/PKB.

Mirza AM, Kohn AD, Roth RA, McMahon M.

Cell Growth Differ. 2000 Jun;11(6):279-92.

8.

Butyrate-treated colonic Caco-2 cells exhibit defective integrin-mediated signaling together with increased apoptosis and differentiation.

Lévy P, Robin H, Bertrand F, Kornprobst M, Capeau J.

J Cell Physiol. 2003 Dec;197(3):336-47.

PMID:
14566963
9.
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12.

The cleavage of Akt/protein kinase B by death receptor signaling is an important event in detachment-induced apoptosis.

Bachelder RE, Wendt MA, Fujita N, Tsuruo T, Mercurio AM.

J Biol Chem. 2001 Sep 14;276(37):34702-7. Epub 2001 Jul 19.

13.

Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion.

Shaw LM, Rabinovitz I, Wang HH, Toker A, Mercurio AM.

Cell. 1997 Dec 26;91(7):949-60.

14.

alpha(v) integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells.

Cruet-Hennequart S, Maubant S, Luis J, Gauduchon P, Staedel C, Dedhar S.

Oncogene. 2003 Mar 20;22(11):1688-702.

PMID:
12642872
15.

Ceramide and reactive oxygen species generated by H2O2 induce caspase-3-independent degradation of Akt/protein kinase B.

Martin D, Salinas M, Fujita N, Tsuruo T, Cuadrado A.

J Biol Chem. 2002 Nov 8;277(45):42943-52. Epub 2002 Sep 3.

16.

A function for the integrin alpha6beta4 in the invasive properties of colorectal carcinoma cells.

Chao C, Lotz MM, Clarke AC, Mercurio AM.

Cancer Res. 1996 Oct 15;56(20):4811-9.

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18.

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis.

Gottlieb TM, Leal JF, Seger R, Taya Y, Oren M.

Oncogene. 2002 Feb 14;21(8):1299-303.

20.

Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons.

Gary DS, Milhavet O, Camandola S, Mattson MP.

J Neurochem. 2003 Feb;84(4):878-90.

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