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Items: 1 to 20 of 98

2.
3.

A novel PTB-PDZ domain interaction mediates isoform-specific ubiquitylation of mammalian Numb.

Nie J, Li SS, McGlade CJ.

J Biol Chem. 2004 May 14;279(20):20807-15.

4.

Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.

Kyriazis GA, Wei Z, Vandermey M, Jo DG, Xin O, Mattson MP, Chan SL.

J Biol Chem. 2008 Sep 12;283(37):25492-502. doi: 10.1074/jbc.M802072200.

5.
6.

Evidence for altered Numb isoform levels in Alzheimer's disease patients and a triple transgenic mouse model.

Chigurupati S, Madan M, Okun E, Wei Z, Pattisapu JV, Mughal MR, Mattson MP, Chan SL.

J Alzheimers Dis. 2011;24(2):349-61. doi: 10.3233/JAD-2011-101797.

PMID:
21258150
7.

A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division.

Qin H, Percival-Smith A, Li C, Jia CY, Gloor G, Li SS.

J Biol Chem. 2004 Mar 19;279(12):11304-12.

8.

LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation.

Nie J, McGill MA, Dermer M, Dho SE, Wolting CD, McGlade CJ.

EMBO J. 2002 Jan 15;21(1-2):93-102.

9.

Asymmetric localization of Numb:EGFP in dividing neuroepithelial cells during neurulation in Danio rerio.

Reugels AM, Boggetti B, Scheer N, Campos-Ortega JA.

Dev Dyn. 2006 Apr;235(4):934-48.

11.

Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb.

Krieger JR, Taylor P, Gajadhar AS, Guha A, Moran MF, McGlade CJ.

Mol Cell Proteomics. 2013 Feb;12(2):499-514. doi: 10.1074/mcp.M112.020768.

12.

Functional analysis of the Numb phosphotyrosine-binding domain using site-directed mutagenesis.

Yaich L, Ooi J, Park M, Borg JP, Landry C, Bodmer R, Margolis B.

J Biol Chem. 1998 Apr 24;273(17):10381-8.

14.

Characterization and role of NUMB in the human extravillous trophopblast.

Haider M, Qiu Q, Bani-Yaghoub M, Tsang BK, Gruslin A.

Placenta. 2011 Jun;32(6):441-9. doi: 10.1016/j.placenta.2011.03.008.

PMID:
21486681
15.

Protein 4.1-mediated membrane targeting of human discs large in epithelial cells.

Hanada T, Takeuchi A, Sondarva G, Chishti AH.

J Biol Chem. 2003 Sep 5;278(36):34445-50.

17.

Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate.

Verdi JM, Schmandt R, Bashirullah A, Jacob S, Salvino R, Craig CG, Program AE, Lipshitz HD, McGlade CJ.

Curr Biol. 1996 Sep 1;6(9):1134-45.

18.

The Lnx family proteins function as molecular scaffolds for Numb family proteins.

Rice DS, Northcutt GM, Kurschner C.

Mol Cell Neurosci. 2001 Nov;18(5):525-40.

PMID:
11922143
19.

Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity.

Li SC, Zwahlen C, Vincent SJ, McGlade CJ, Kay LE, Pawson T, Forman-Kay JD.

Nat Struct Biol. 1998 Dec;5(12):1075-83.

PMID:
9846878
20.

Stress-induced switch in Numb isoforms enhances Notch-dependent expression of subtype-specific transient receptor potential channel.

Kyriazis GA, Belal C, Madan M, Taylor DG, Wang J, Wei Z, Pattisapu JV, Chan SL.

J Biol Chem. 2010 Feb 26;285(9):6811-25. doi: 10.1074/jbc.M109.074690.

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