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Items: 1 to 20 of 100

1.

PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance.

Kubota N, Terauchi Y, Miki H, Tamemoto H, Yamauchi T, Komeda K, Satoh S, Nakano R, Ishii C, Sugiyama T, Eto K, Tsubamoto Y, Okuno A, Murakami K, Sekihara H, Hasegawa G, Naito M, Toyoshima Y, Tanaka S, Shiota K, Kitamura T, Fujita T, Ezaki O, Aizawa S, Kadowaki T, et al.

Mol Cell. 1999 Oct;4(4):597-609.

2.

The role of PPARgamma in high-fat diet-induced obesity and insulin resistance.

Kadowaki T, Hara K, Kubota N, Tobe K, Terauchi Y, Yamauchi T, Eto K, Kadowaki H, Noda M, Hagura R, Akanuma Y.

J Diabetes Complications. 2002 Jan-Feb;16(1):41-5. Review.

PMID:
11872365
3.

The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance.

Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K, Komeda K, Ide T, Kubota N, Terauchi Y, Tobe K, Miki H, Tsuchida A, Akanuma Y, Nagai R, Kimura S, Kadowaki T.

J Biol Chem. 2001 Nov 2;276(44):41245-54. Epub 2001 Aug 31.

4.

Role of PPAR gamma in regulating adipocyte differentiation and insulin-responsive glucose uptake.

Hamm JK, el Jack AK, Pilch PF, Farmer SR.

Ann N Y Acad Sci. 1999 Nov 18;892:134-45.

PMID:
10842659
5.

Pan-PPAR agonist beneficial effects in overweight mice fed a high-fat high-sucrose diet.

Fernandes-Santos C, Carneiro RE, de Souza Mendonca L, Aguila MB, Mandarim-de-Lacerda CA.

Nutrition. 2009 Jul-Aug;25(7-8):818-27. doi: 10.1016/j.nut.2008.12.010. Epub 2009 Mar 5.

PMID:
19268533
6.

Differential influences of peroxisome proliferator-activated receptors gamma and -alpha on food intake and energy homeostasis.

Larsen PJ, Jensen PB, Sørensen RV, Larsen LK, Vrang N, Wulff EM, Wassermann K.

Diabetes. 2003 Sep;52(9):2249-59.

7.

The role of PPARgamma as a thrifty gene both in mice and humans.

Hara K, Kubota N, Tobe K, Terauchi Y, Miki H, Komeda K, Tamemoto H, Yamauchi T, Hagura R, Ito C, Akanuma Y, Kadowaki T.

Br J Nutr. 2000 Dec;84 Suppl 2:S235-9.

PMID:
11242476
9.

Novel genes regulated by the insulin sensitizer rosiglitazone during adipocyte differentiation.

Albrektsen T, Frederiksen KS, Holmes WE, Boel E, Taylor K, Fleckner J.

Diabetes. 2002 Apr;51(4):1042-51.

10.

Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-gamma-deficient mice on a high-fat diet.

Matsui J, Terauchi Y, Kubota N, Takamoto I, Eto K, Yamashita T, Komeda K, Yamauchi T, Kamon J, Kita S, Noda M, Kadowaki T.

Diabetes. 2004 Nov;53(11):2844-54.

11.

Impact of increased PPARgamma activity in adipocytes in vivo on adiposity, insulin sensitivity and the effects of rosiglitazone treatment.

Takasawa K, Kubota N, Terauchi Y, Kadowaki T.

Endocr J. 2008 Aug;55(4):767-76. Epub 2008 May 28.

12.

PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.

Guerre-Millo M, Rouault C, Poulain P, André J, Poitout V, Peters JM, Gonzalez FJ, Fruchart JC, Reach G, Staels B.

Diabetes. 2001 Dec;50(12):2809-14.

13.

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

Gavrilova O, Haluzik M, Matsusue K, Cutson JJ, Johnson L, Dietz KR, Nicol CJ, Vinson C, Gonzalez FJ, Reitman ML.

J Biol Chem. 2003 Sep 5;278(36):34268-76. Epub 2003 Jun 11.

14.

Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation.

Koh EH, Kim MS, Park JY, Kim HS, Youn JY, Park HS, Youn JH, Lee KU.

Diabetes. 2003 Sep;52(9):2331-7.

15.

A novel peroxisome proliferator-activated gamma (PPAR gamma) agonist, CLX-0921, has potent antihyperglycemic activity with low adipogenic potential.

Dey D, Medicherla S, Neogi P, Gowri M, Cheng J, Gross C, Sharma SD, Reaven GM, Nag B.

Metabolism. 2003 Aug;52(8):1012-8.

PMID:
12898466
16.

Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.

Iwata M, Haruta T, Usui I, Takata Y, Takano A, Uno T, Kawahara J, Ueno E, Sasaoka T, Ishibashi O, Kobayashi M.

Diabetes. 2001 May;50(5):1083-92.

17.

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma).

Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA.

J Biol Chem. 1995 Jun 2;270(22):12953-6.

18.

Hypertension and insulin resistance: role of peroxisome proliferator-activated receptor gamma.

Itoh H, Doi K, Tanaka T, Fukunaga Y, Hosoda K, Inoue G, Nishimura H, Yoshimasa Y, Yamori Y, Nakao K.

Clin Exp Pharmacol Physiol. 1999 Jul;26(7):558-60.

PMID:
10405788
19.

Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation.

Hosooka T, Noguchi T, Kotani K, Nakamura T, Sakaue H, Inoue H, Ogawa W, Tobimatsu K, Takazawa K, Sakai M, Matsuki Y, Hiramatsu R, Yasuda T, Lazar MA, Yamanashi Y, Kasuga M.

Nat Med. 2008 Feb;14(2):188-93. doi: 10.1038/nm1706. Epub 2008 Jan 20.

PMID:
18204460
20.

[PPAR gamma agonist and antagonist].

Kadowaki T.

Nihon Yakurigaku Zasshi. 2001 Nov;118(5):321-6. Review. Japanese.

PMID:
11729635

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