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Items: 1 to 20 of 254

1.

Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus.

Harvey BG, Leopold PL, Hackett NR, Grasso TM, Williams PM, Tucker AL, Kaner RJ, Ferris B, Gonda I, Sweeney TD, Ramalingam R, Kovesdi I, Shak S, Crystal RG.

J Clin Invest. 1999 Nov;104(9):1245-55.

2.

Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications.

Joseph PM, O'Sullivan BP, Lapey A, Dorkin H, Oren J, Balfour R, Perricone MA, Rosenberg M, Wadsworth SC, Smith AE, St George JA, Meeker DP.

Hum Gene Ther. 2001 Jul 20;12(11):1369-82.

PMID:
11485629
3.

[Aerosol administration of a replication defective recombinant adenovirus expressing normal human cDNA-CFTR in the respiratory tractus in patients with cystic fibrosis].

Bellon G, Calmard L, Thouvenot D, Levrey H, Jagneaux V, Poitevin F, Malcus C, Accart N, Séné C, Layani MP, Aymard M, Bienvenu J, Courtney M, Döring G, Gilly B, Gilly R, Lamy D, Morel Y, Paulin C, Perraud F, Rodillon L, So S, Touraine F, Schatz C, Pavirani A.

C R Seances Soc Biol Fil. 1996;190(1):109-42. French.

PMID:
8881273
4.

Gene therapy for the respiratory manifestations of cystic fibrosis.

Korst RJ, McElvaney NG, Chu CS, Rosenfeld MA, Mastrangeli A, Hay J, Brody SL, Eissa NT, Danel C, Jaffe HA, et al.

Am J Respir Crit Care Med. 1995 Mar;151(3 Pt 2):S75-87. Review.

PMID:
7533609
5.

Vector-specific complementation profiles of two independent primary defects in cystic fibrosis airways.

Zhang Y, Jiang Q, Dudus L, Yankaskas JR, Engelhardt JF.

Hum Gene Ther. 1998 Mar 20;9(5):635-48.

PMID:
9551612
6.

Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. II. Transfection efficiency in airway epithelium.

Perricone MA, Morris JE, Pavelka K, Plog MS, O'Sullivan BP, Joseph PM, Dorkin H, Lapey A, Balfour R, Meeker DP, Smith AE, Wadsworth SC, St George JA.

Hum Gene Ther. 2001 Jul 20;12(11):1383-94.

PMID:
11485630
7.

Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis.

Crystal RG, McElvaney NG, Rosenfeld MA, Chu CS, Mastrangeli A, Hay JG, Brody SL, Jaffe HA, Eissa NT, Danel C.

Nat Genet. 1994 Sep;8(1):42-51.

PMID:
7527271
10.

Adenovirus 5-fiber 35 chimeric vector mediates efficient apical correction of the cystic fibrosis transmembrane conductance regulator defect in cystic fibrosis primary airway epithelia.

Granio O, Ashbourne Excoffon KJ, Henning P, Melin P, Norez C, Gonzalez G, Karp PH, Magnusson MK, Habib N, Lindholm L, Becq F, Boulanger P, Zabner J, Hong SS.

Hum Gene Ther. 2010 Mar;21(3):251-69. doi: 10.1089/hum.2009.056.

PMID:
19788389
11.
12.

In vivo adenovirus-mediated transfer of human CFTR cDNA to rhesus monkey airway epithelium: efficacy, toxicity and safety.

Bout A, Imler JL, Schultz H, Perricaudet M, Zurcher C, Herbrink P, Valerio D, Pavirani A.

Gene Ther. 1994 Nov;1(6):385-94.

PMID:
7584104
14.

Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study.

Flotte TR, Zeitlin PL, Reynolds TC, Heald AE, Pedersen P, Beck S, Conrad CK, Brass-Ernst L, Humphries M, Sullivan K, Wetzel R, Taylor G, Carter BJ, Guggino WB.

Hum Gene Ther. 2003 Jul 20;14(11):1079-88.

PMID:
12885347
15.
16.

A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis.

Knowles MR, Hohneker KW, Zhou Z, Olsen JC, Noah TL, Hu PC, Leigh MW, Engelhardt JF, Edwards LJ, Jones KR, et al.

N Engl J Med. 1995 Sep 28;333(13):823-31.

17.

Variability of human systemic humoral immune responses to adenovirus gene transfer vectors administered to different organs.

Harvey BG, Hackett NR, El-Sawy T, Rosengart TK, Hirschowitz EA, Lieberman MD, Lesser ML, Crystal RG.

J Virol. 1999 Aug;73(8):6729-42.

18.

Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats.

Zabner J, Petersen DM, Puga AP, Graham SM, Couture LA, Keyes LD, Lukason MJ, St George JA, Gregory RJ, Smith AE, et al.

Nat Genet. 1994 Jan;6(1):75-83.

PMID:
7511023
19.

Partial correction of endogenous DeltaF508 CFTR in human cystic fibrosis airway epithelia by spliceosome-mediated RNA trans-splicing.

Liu X, Jiang Q, Mansfield SG, Puttaraju M, Zhang Y, Zhou W, Cohn JA, Garcia-Blanco MA, Mitchell LG, Engelhardt JF.

Nat Biotechnol. 2002 Jan;20(1):47-52.

PMID:
11753361
20.

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