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Items: 1 to 20 of 281

1.

Intra-articular delivery of a herpes simplex virus IL-1Ra gene vector reduces inflammation in a rabbit model of arthritis.

Oligino T, Ghivizzani S, Wolfe D, Lechman E, Krisky D, Mi Z, Evans C, Robbins P, Glorioso J.

Gene Ther. 1999 Oct;6(10):1713-20.

2.

Suppression of experimental osteoarthritis by adenovirus-mediated double gene transfer.

Wang HJ, Yu CL, Kishi H, Motoki K, Mao ZB, Muraguchi A.

Chin Med J (Engl). 2006 Aug 20;119(16):1365-73.

PMID:
16934183
3.

Adenoviral delivery of IL-1 receptor antagonist abrogates disease activity during the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.

Hur W, Cho ML, Yoon SK, Kim SY, Ju JH, Jhun JY, Heo SB, Moon YM, Min SY, Park SH, Kim HY.

Immunol Lett. 2006 Aug 15;106(2):154-62. Epub 2006 Jun 5.

PMID:
16793145
4.

Interleukin-1 receptor antagonist gene therapy for arthritis.

Krishnan BR.

Curr Opin Mol Ther. 1999 Aug;1(4):454-7. Review.

PMID:
11713759
5.
6.
7.

Intra-articular IL-4 gene therapy in arthritis: anti-inflammatory effect and enhanced th2activity.

Boyle DL, Nguyen KH, Zhuang S, Shi Y, McCormack JE, Chada S, Firestein GS.

Gene Ther. 1999 Dec;6(12):1911-8.

8.

A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis.

Arntz OJ, Geurts J, Veenbergen S, Bennink MB, van den Brand BT, Abdollahi-Roodsaz S, van den Berg WB, van de Loo FA.

Arthritis Res Ther. 2010;12(2):R61. doi: 10.1186/ar2974. Epub 2010 Apr 6.

9.

Enhanced gene transfer to arthritic joints using adeno-associated virus type 5: implications for intra-articular gene therapy.

Adriaansen J, Tas SW, Klarenbeek PL, Bakker AC, Apparailly F, Firestein GS, Jorgensen C, Vervoordeldonk MJ, Tak PP.

Ann Rheum Dis. 2005 Dec;64(12):1677-84. Epub 2005 May 5.

10.

Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy.

Nixon AJ, Haupt JL, Frisbie DD, Morisset SS, McIlwraith CW, Robbins PD, Evans CH, Ghivizzani S.

Gene Ther. 2005 Jan;12(2):177-86.

PMID:
15578043
11.

In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy.

Pelletier JP, Caron JP, Evans C, Robbins PD, Georgescu HI, Jovanovic D, Fernandes JC, Martel-Pelletier J.

Arthritis Rheum. 1997 Jun;40(6):1012-9.

PMID:
9182910
12.

Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction.

Lubberts E, Joosten LA, van Den Bersselaar L, Helsen MM, Bakker AC, van Meurs JB, Graham FL, Richards CD, van Den Berg WB.

J Immunol. 1999 Oct 15;163(8):4546-56.

13.

Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway.

Neumann E, Judex M, Kullmann F, Grifka J, Robbins PD, Pap T, Gay RE, Evans CH, Gay S, Schölmerich J, Müller-Ladner U.

Gene Ther. 2002 Nov;9(22):1508-19.

15.

Direct adenoviral gene transfer of viral IL-10 to rabbit knees with experimental arthritis ameliorates disease in both injected and contralateral control knees.

Lechman ER, Jaffurs D, Ghivizzani SC, Gambotto A, Kovesdi I, Mi Z, Evans CH, Robbins PD.

J Immunol. 1999 Aug 15;163(4):2202-8.

16.

Local delivery of a recombinant adenoassociated vector containing a tumour necrosis factor alpha antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study.

Mease PJ, Hobbs K, Chalmers A, El-Gabalawy H, Bookman A, Keystone E, Furst DE, Anklesaria P, Heald AE.

Ann Rheum Dis. 2009 Aug;68(8):1247-54. doi: 10.1136/ard.2008.089375. Epub 2008 Aug 4.

PMID:
18678578
17.

Intra-articular adenoviral-mediated gene transfer of trail induces apoptosis of arthritic rabbit synovium.

Yao Q, Wang S, Gambotto A, Glorioso JC, Evans CH, Robbins PD, Ghivizzani SC, Oligino TJ.

Gene Ther. 2003 Jun;10(12):1055-60.

PMID:
12776164
18.

Joint capsule treatment with enkephalin-encoding HSV-1 recombinant vector reduces inflammatory damage and behavioural sequelae in rat CFA monoarthritis.

Lu Y, McNearney TA, Wilson SP, Yeomans DC, Westlund KN.

Eur J Neurosci. 2008 Mar;27(5):1153-65. doi: 10.1111/j.1460-9568.2008.06076.x.

PMID:
18364035
20.

Suppression of intra-articular responses to interleukin-1 by transfer of the interleukin-1 receptor antagonist gene to synovium.

Hung GL, Galea-Lauri J, Mueller GM, Georgescu HI, Larkin LA, Suchanek MK, Tindal MH, Robbins PD, Evans CH.

Gene Ther. 1994 Jan;1(1):64-9.

PMID:
7584062

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