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Items: 1 to 20 of 244

1.

Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus.

Shimomura I, Bashmakov Y, Horton JD.

J Biol Chem. 1999 Oct 15;274(42):30028-32.

2.

Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver.

Horton JD, Shimomura I, Ikemoto S, Bashmakov Y, Hammer RE.

J Biol Chem. 2003 Sep 19;278(38):36652-60. Epub 2003 Jul 10.

4.

Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs.

Matsuzaka T, Shimano H, Yahagi N, Yoshikawa T, Amemiya-Kudo M, Hasty AH, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Takahashi A, Yato S, Sone H, Ishibashi S, Yamada N.

J Lipid Res. 2002 Jun;43(6):911-20.

5.

Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression.

Dentin R, Pégorier JP, Benhamed F, Foufelle F, Ferré P, Fauveau V, Magnuson MA, Girard J, Postic C.

J Biol Chem. 2004 May 7;279(19):20314-26. Epub 2004 Feb 25.

7.

A crucial role of sterol regulatory element-binding protein-1 in the regulation of lipogenic gene expression by polyunsaturated fatty acids.

Yahagi N, Shimano H, Hasty AH, Amemiya-Kudo M, Okazaki H, Tamura Y, Iizuka Y, Shionoiri F, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N.

J Biol Chem. 1999 Dec 10;274(50):35840-4.

9.

Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression.

Sekiya M, Yahagi N, Matsuzaka T, Najima Y, Nakakuki M, Nagai R, Ishibashi S, Osuga J, Yamada N, Shimano H.

Hepatology. 2003 Dec;38(6):1529-39.

PMID:
14647064
10.

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.

Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N.

J Biol Chem. 2002 May 31;277(22):19353-7. Epub 2002 Mar 28.

11.

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.

Kammoun HL, Chabanon H, Hainault I, Luquet S, Magnan C, Koike T, Ferré P, Foufelle F.

J Clin Invest. 2009 May;119(5):1201-15. doi: 10.1172/JCI37007. Epub 2009 Apr 13.

12.
13.

Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes.

Shimano H, Yahagi N, Amemiya-Kudo M, Hasty AH, Osuga J, Tamura Y, Shionoiri F, Iizuka Y, Ohashi K, Harada K, Gotoda T, Ishibashi S, Yamada N.

J Biol Chem. 1999 Dec 10;274(50):35832-9.

14.
15.

Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha.

Matsuzaka T, Shimano H, Yahagi N, Amemiya-Kudo M, Yoshikawa T, Hasty AH, Tamura Y, Osuga J, Okazaki H, Iizuka Y, Takahashi A, Sone H, Gotoda T, Ishibashi S, Yamada N.

J Lipid Res. 2002 Jan;43(1):107-14.

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17.

Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene.

Amemiya-Kudo M, Shimano H, Yoshikawa T, Yahagi N, Hasty AH, Okazaki H, Tamura Y, Shionoiri F, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Sato R, Kimura S, Ishibashi S, Yamada N.

J Biol Chem. 2000 Oct 6;275(40):31078-85.

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19.

Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis.

Zhang YL, Hernandez-Ono A, Siri P, Weisberg S, Conlon D, Graham MJ, Crooke RM, Huang LS, Ginsberg HN.

J Biol Chem. 2006 Dec 8;281(49):37603-15. Epub 2006 Sep 12.

20.

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