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Items: 1 to 20 of 432

1.

Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein.

Hahm KB, Cho K, Lee C, Im YH, Chang J, Choi SG, Sorensen PH, Thiele CJ, Kim SJ.

Nat Genet. 1999 Oct;23(2):222-7. Erratum in: Nat Genet 1999 Dec;23(4):481.

PMID:
10508522
2.

EWS-FLI1, EWS-ERG, and EWS-ETV1 oncoproteins of Ewing tumor family all suppress transcription of transforming growth factor beta type II receptor gene.

Im YH, Kim HT, Lee C, Poulin D, Welford S, Sorensen PH, Denny CT, Kim SJ.

Cancer Res. 2000 Mar 15;60(6):1536-40.

3.

Induction of tenascin-C by tumor-specific EWS-ETS fusion genes.

Watanabe G, Nishimori H, Irifune H, Sasaki Y, Ishida S, Zembutsu H, Tanaka T, Kawaguchi S, Wada T, Hata J, Kusakabe M, Yoshida K, Nakamura Y, Tokino T.

Genes Chromosomes Cancer. 2003 Mar;36(3):224-32.

PMID:
12557222
4.

The EWS/FLI1 oncogenic protein inhibits expression of the Wnt inhibitor DICKKOPF-1 gene and antagonizes beta-catenin/TCF-mediated transcription.

Navarro D, Agra N, Pestaña A, Alonso J, González-Sancho JM.

Carcinogenesis. 2010 Mar;31(3):394-401. doi: 10.1093/carcin/bgp317.

5.

Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma.

Lin PP, Brody RI, Hamelin AC, Bradner JE, Healey JH, Ladanyi M.

Cancer Res. 1999 Apr 1;59(7):1428-32.

6.

EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene.

Thompson AD, Braun BS, Arvand A, Stewart SD, May WA, Chen E, Korenberg J, Denny C.

Oncogene. 1996 Dec 19;13(12):2649-58.

PMID:
9000139
7.
8.

Suppression of the Ewing's sarcoma phenotype by FLI1/ERF repressor hybrids.

Athanasiou M, LeGallic L, Watson DK, Blair DG, Mavrothalassitis G.

Cancer Gene Ther. 2000 Aug;7(8):1188-95.

9.

EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro.

Kovar H, Aryee DN, Jug G, Henöckl C, Schemper M, Delattre O, Thomas G, Gadner H.

Cell Growth Differ. 1996 Apr;7(4):429-37.

10.

Homotypic and heterotypic interactions of EWS, FLI1 and their oncogenic fusion protein.

Spahn L, Siligan C, Bachmaier R, Schmid JA, Aryee DN, Kovar H.

Oncogene. 2003 Oct 9;22(44):6819-29.

PMID:
14534527
11.

DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells.

García-Aragoncillo E, Carrillo J, Lalli E, Agra N, Gómez-López G, Pestaña A, Alonso J.

Oncogene. 2008 Oct 9;27(46):6034-43. doi: 10.1038/onc.2008.203.

PMID:
18591936
12.
13.

EWS/ETS fusions activate telomerase in Ewing's tumors.

Takahashi A, Higashino F, Aoyagi M, Yoshida K, Itoh M, Kyo S, Ohno T, Taira T, Ariga H, Nakajima K, Hatta M, Kobayashi M, Sano H, Kohgo T, Shindoh M.

Cancer Res. 2003 Dec 1;63(23):8338-44.

14.

Treatment of Ewing's sarcoma using an antisense oligodeoxynucleotide to regulate the cell cycle.

Asami S, Chin M, Shichino H, Yoshida Y, Nemoto N, Mugishima H, Suzuki T.

Biol Pharm Bull. 2008 Mar;31(3):391-4.

15.

Identification of p21WAF1/CIP1 as a direct target of EWS-Fli1 oncogenic fusion protein.

Nakatani F, Tanaka K, Sakimura R, Matsumoto Y, Matsunobu T, Li X, Hanada M, Okada T, Iwamoto Y.

J Biol Chem. 2003 Apr 25;278(17):15105-15.

16.

EWS-Fli1 up-regulates expression of the Aurora A and Aurora B kinases.

Wakahara K, Ohno T, Kimura M, Masuda T, Nozawa S, Dohjima T, Yamamoto T, Nagano A, Kawai G, Matsuhashi A, Saitoh M, Takigami I, Okano Y, Shimizu K.

Mol Cancer Res. 2008 Dec;6(12):1937-45. doi: 10.1158/1541-7786.MCR-08-0054.

17.

The COOH-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-1.

Arvand A, Welford SM, Teitell MA, Denny CT.

Cancer Res. 2001 Jul 1;61(13):5311-7.

18.

Aberrant laminin beta3 isoforms downstream of EWS-ETS fusion genes in Ewing family tumors.

Irifune H, Nishimori H, Watanabe G, Yoshida K, Ikeda T, Matsui C, Morohashi M, Kawaguchi S, Nagoya S, Wada T, Yamashita T, Nakamura Y, Tokino T.

Cancer Biol Ther. 2005 Apr;4(4):449-55.

PMID:
15846078
19.

Downregulation and forced expression of EWS-Fli1 fusion gene results in changes in the expression of G(1)regulatory genes.

Matsumoto Y, Tanaka K, Nakatani F, Matsunobu T, Matsuda S, Iwamoto Y.

Br J Cancer. 2001 Mar 23;84(6):768-75.

20.
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