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Items: 1 to 20 of 267

1.

Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome.

James SJ, Pogribna M, Pogribny IP, Melnyk S, Hine RJ, Gibson JB, Yi P, Tafoya DL, Swenson DH, Wilson VL, Gaylor DW.

Am J Clin Nutr. 1999 Oct;70(4):495-501.

2.

Gene polymorphism and folate metabolism: a maternal risk factor for Down syndrome.

Sheth JJ, Sheth FJ.

Indian Pediatr. 2003 Feb;40(2):115-23.

PMID:
12626825
3.

Abnormal folate metabolism and genetic polymorphism of the folate pathway in a child with Down syndrome and neural tube defect.

Al-Gazali LI, Padmanabhan R, Melnyk S, Yi P, Pogribny IP, Pogribna M, Bakir M, Hamid ZA, Abdulrazzaq Y, Dawodu A, James SJ.

Am J Med Genet. 2001 Oct 1;103(2):128-32.

PMID:
11568918
5.

[The relationship between polymorphism of gene involved in folate metabolism, homocysteine level and risk of Down syndrome].

Wang W, Xie W, Wang Xy.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2007 Oct;24(5):533-7. Chinese.

PMID:
17922421
6.

Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.

Ma J, Stampfer MJ, Giovannucci E, Artigas C, Hunter DJ, Fuchs C, Willett WC, Selhub J, Hennekens CH, Rozen R.

Cancer Res. 1997 Mar 15;57(6):1098-102.

7.

Folate levels and N(5),N(10)-methylenetetrahydrofolate reductase genotype (MTHFR) in mothers of offspring with neural tube defects: a case-control study.

Martínez de Villarreal LE, Delgado-Enciso I, Valdéz-Leal R, Ortíz-López R, Rojas-Martínez A, Limón-Benavides C, Sánchez-Peña MA, Ancer-Rodríguez J, Barrera-Saldaña HA, Villarreal-Pérez JZ.

Arch Med Res. 2001 Jul-Aug;32(4):277-82.

PMID:
11440783
8.

Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome?

Martínez-Frías ML, Pérez B, Desviat LR, Castro M, Leal F, Rodríguez L, Mansilla E, Martínez-Fernández ML, Bermejo E, Rodríguez-Pinilla E, Prieto D, Ugarte M; ECEMC Working Group.

Am J Med Genet A. 2006 May 1;140(9):987-97.

PMID:
16575899
9.

MTRR and MTHFR polymorphism: link to Down syndrome?

O'Leary VB, Parle-McDermott A, Molloy AM, Kirke PN, Johnson Z, Conley M, Scott JM, Mills JL.

Am J Med Genet. 2002 Jan 15;107(2):151-5.

PMID:
11807890
10.

Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome in China.

Wang SS, Qiao FY, Feng L, Lv JJ.

J Zhejiang Univ Sci B. 2008 Feb;9(2):93-9. doi: 10.1631/jzus.B0710599.

11.

A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida.

Wilson A, Platt R, Wu Q, Leclerc D, Christensen B, Yang H, Gravel RA, Rozen R.

Mol Genet Metab. 1999 Aug;67(4):317-23.

PMID:
10444342
12.

Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome.

Hobbs CA, Sherman SL, Yi P, Hopkins SE, Torfs CP, Hine RJ, Pogribna M, Rozen R, James SJ.

Am J Hum Genet. 2000 Sep;67(3):623-30. Epub 2000 Aug 7.

13.

Methylenetetrahydrofolate reductase enzyme polymorphisms as maternal risk for Down syndrome among Turkish women.

Boduroğlu K, Alanay Y, Koldan B, Tunçbilek E.

Am J Med Genet A. 2004 May 15;127A(1):5-10.

PMID:
15103709
14.

[Mutations in the methylene-tetrahydrofolate reductase gene and Down syndrome].

Grillo LB, Acácio GL, Barini R, Pinto W Jr, Bertuzzo CS.

Cad Saude Publica. 2002 Nov-Dec;18(6):1795-7. Portuguese.

15.

Abnormal folate metabolism in mothers with Down syndrome offspring: review of the literature.

Eskes TK.

Eur J Obstet Gynecol Reprod Biol. 2006 Feb 1;124(2):130-3. Epub 2005 Oct 5. Review.

PMID:
16169148
16.

Methylenetetrahydrofolate reductase 677C-->T genotype modulates homocysteine responses to a folate-rich diet or a low-dose folic acid supplement: a randomized controlled trial.

Ashfield-Watt PA, Pullin CH, Whiting JM, Clark ZE, Moat SJ, Newcombe RG, Burr ML, Lewis MJ, Powers HJ, McDowell IF.

Am J Clin Nutr. 2002 Jul;76(1):180-6.

17.

Genetic polymorphisms involved in folate metabolism and elevated plasma concentrations of homocysteine: maternal risk factors for Down syndrome in Brazil.

Biselli JM, Goloni-Bertollo EM, Zampieri BL, Haddad R, Eberlin MN, Pavarino-Bertelli EC.

Genet Mol Res. 2008 Jan 22;7(1):33-42.

18.

A common mutation in the methylenetetrahydrofolate reductase gene and risk of coronary heart disease: results among U.S. men.

Verhoef P, Rimm EB, Hunter DJ, Chen J, Willett WC, Kelsey K, Stampfer MJ.

J Am Coll Cardiol. 1998 Aug;32(2):353-9.

19.

Influence of methylenetetrahydrofolate reductase genotype, age, vitamin B-12, and folate status on plasma homocysteine in children.

Delvin EE, Rozen R, Merouani A, Genest J Jr, Lambert M.

Am J Clin Nutr. 2000 Dec;72(6):1469-73.

20.

Folate intake, serum homocysteine and methylenetetrahydrofolate reductase (MTHFR) C677T genotype are not associated with oral cancer risk in Puerto Rico.

Weinstein SJ, Gridley G, Harty LC, Diehl SR, Brown LM, Winn DM, Bravo-Otero E, Hayes RB.

J Nutr. 2002 Apr;132(4):762-7.

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