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Items: 1 to 20 of 72

1.

Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice.

Saigoh K, Wang YL, Suh JG, Yamanishi T, Sakai Y, Kiyosawa H, Harada T, Ichihara N, Wakana S, Kikuchi T, Wada K.

Nat Genet. 1999 Sep;23(1):47-51.

PMID:
10471497
2.

Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia.

Kurihara LJ, Kikuchi T, Wada K, Tilghman SM.

Hum Mol Genet. 2001 Sep 1;10(18):1963-70.

PMID:
11555633
3.

Characterization of the testis in congenitally ubiquitin carboxy-terminal hydrolase-1 (Uch-L1) defective (gad) mice.

Kwon J, Kikuchi T, Setsuie R, Ishii Y, Kyuwa S, Yoshikawa Y.

Exp Anim. 2003 Jan;52(1):1-9.

4.

[The ubiquitin-proteasome system and neurodegeneration].

Wada K, Osaka H, Aoki S, Wang YL.

Rinsho Shinkeigaku. 2001 Dec;41(12):1072-4. Review. Japanese.

PMID:
12235799
5.

Proteomic and histochemical analysis of proteins involved in the dying-back-type of axonal degeneration in the gracile axonal dystrophy (gad) mouse.

Goto A, Wang YL, Kabuta T, Setsuie R, Osaka H, Sawa A, Ishiura S, Wada K.

Neurochem Int. 2009 May-Jun;54(5-6):330-8. doi: 10.1016/j.neuint.2008.12.012. Epub 2008 Dec 25.

PMID:
19154771
6.

Ubiquitin carboxy-terminal hydrolase L1 binds to and stabilizes monoubiquitin in neuron.

Osaka H, Wang YL, Takada K, Takizawa S, Setsuie R, Li H, Sato Y, Nishikawa K, Sun YJ, Sakurai M, Harada T, Hara Y, Kimura I, Chiba S, Namikawa K, Kiyama H, Noda M, Aoki S, Wada K.

Hum Mol Genet. 2003 Aug 15;12(16):1945-58.

PMID:
12913066
7.

Reduction in memory in passive avoidance learning, exploratory behaviour and synaptic plasticity in mice with a spontaneous deletion in the ubiquitin C-terminal hydrolase L1 gene.

Sakurai M, Sekiguchi M, Zushida K, Yamada K, Nagamine S, Kabuta T, Wada K.

Eur J Neurosci. 2008 Feb;27(3):691-701. doi: 10.1111/j.1460-9568.2008.06047.x.

PMID:
18279321
8.
9.

Sulfatide accumulation in the dystrophic terminals of gracile axonal dystrophy mice: lipid analysis using matrix-assisted laser desorption/ionization imaging mass spectrometry.

Onishi S, Tatsumi Y, Wada K, Yang HJ, Sugiura Y, Setou M, Yoshikawa H.

Med Mol Morphol. 2013 Sep;46(3):160-5. doi: 10.1007/s00795-013-0019-y. Epub 2013 Feb 16.

PMID:
23417724
10.

The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice.

Mi W, Beirowski B, Gillingwater TH, Adalbert R, Wagner D, Grumme D, Osaka H, Conforti L, Arnhold S, Addicks K, Wada K, Ribchester RR, Coleman MP.

Brain. 2005 Feb;128(Pt 2):405-16. Epub 2005 Jan 11.

PMID:
15644421
11.

Accumulation of beta- and gamma-synucleins in the ubiquitin carboxyl-terminal hydrolase L1-deficient gad mouse.

Wang YL, Takeda A, Osaka H, Hara Y, Furuta A, Setsuie R, Sun YJ, Kwon J, Sato Y, Sakurai M, Noda M, Yoshikawa Y, Wada K.

Brain Res. 2004 Sep 3;1019(1-2):1-9.

PMID:
15306232
12.

Developmental regulation of ubiquitin C-terminal hydrolase isozyme expression during spermatogenesis in mice.

Kwon J, Wang YL, Setsuie R, Sekiguchi S, Sakurai M, Sato Y, Lee WW, Ishii Y, Kyuwa S, Noda M, Wada K, Yoshikawa Y.

Biol Reprod. 2004 Aug;71(2):515-21. Epub 2004 Apr 14.

PMID:
15084487
13.

Deficiency of ubiquitin carboxy-terminal hydrolase-L1 (UCH-L1) leads to vulnerability to lipid peroxidation.

Nagamine S, Kabuta T, Furuta A, Yamamoto K, Takahashi A, Wada K.

Neurochem Int. 2010 Sep;57(2):102-10. doi: 10.1016/j.neuint.2010.04.015. Epub 2010 May 4.

PMID:
20447430
14.

Two closely related ubiquitin C-terminal hydrolase isozymes function as reciprocal modulators of germ cell apoptosis in cryptorchid testis.

Kwon J, Wang YL, Setsuie R, Sekiguchi S, Sato Y, Sakurai M, Noda M, Aoki S, Yoshikawa Y, Wada K.

Am J Pathol. 2004 Oct;165(4):1367-74.

15.

Localization of ubiquitin C-terminal hydrolase L1 in mouse ova and its function in the plasma membrane to block polyspermy.

Sekiguchi S, Kwon J, Yoshida E, Hamasaki H, Ichinose S, Hideshima M, Kuraoka M, Takahashi A, Ishii Y, Kyuwa S, Wada K, Yoshikawa Y.

Am J Pathol. 2006 Nov;169(5):1722-9.

16.

[Ubiquitin immunoreactivity in the central nervous system of gracile axonal dystrophy (GAD) mouse].

Wu J, Ichihara N, Chui DH, Yamazaki K, Kikuchi T.

No To Shinkei. 1995 Sep;47(9):881-5. Japanese.

PMID:
7546937
17.

Microarray expression analysis of gad mice implicates involvement of Parkinson's disease associated UCH-L1 in multiple metabolic pathways.

Bonin M, Poths S, Osaka H, Wang YL, Wada K, Riess O.

Brain Res Mol Brain Res. 2004 Jul 5;126(1):88-97.

PMID:
15207921
18.

YAC/BAC-based physical and transcript mapping around the gracile axonal dystrophy (gad) locus identifies Uchl1, Pmx2b, Atp3a2, and Hip2 genes.

Wang Y, Saigoh K, Osaka H, Yamanishi T, Suh J, Kiyosawa H, Sakai Y, Wakana S, Wada K.

Genomics. 2000 Jun 15;66(3):333-6.

PMID:
10873389
19.

Cloning, expression, and mapping of a mouse gene, Uchl4, highly homologous to human and mouse Uchl3.

Osawa Y, Wang YL, Osaka H, Aoki S, Wada K.

Biochem Biophys Res Commun. 2001 May 11;283(3):627-33.

PMID:
11341770
20.

Ubiquitin dimers control the hydrolase activity of UCH-L3.

Setsuie R, Sakurai M, Sakaguchi Y, Wada K.

Neurochem Int. 2009 May-Jun;54(5-6):314-21. doi: 10.1016/j.neuint.2008.12.013. Epub 2008 Dec 25.

PMID:
19154770

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