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Items: 1 to 20 of 86

1.

Cytochrome P-450 3A4: regulation and role in drug metabolism.

Guengerich FP.

Annu Rev Pharmacol Toxicol. 1999;39:1-17. Review.

PMID:
10331074
2.

Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions.

Tang W, Stearns RA.

Curr Drug Metab. 2001 Jun;2(2):185-98. Review.

PMID:
11469725
3.

Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor.

Goodwin B, Hodgson E, D'Costa DJ, Robertson GR, Liddle C.

Mol Pharmacol. 2002 Aug;62(2):359-65.

4.

Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells.

Schuetz JD, Schuetz EG, Thottassery JV, Guzelian PS, Strom S, Sun D.

Mol Pharmacol. 1996 Jan;49(1):63-72.

PMID:
8569713
5.
6.

Role of a potent inhibitory monoclonal antibody to cytochrome P-450 3A4 in assessment of human drug metabolism.

Mei Q, Tang C, Assang C, Lin Y, Slaughter D, Rodrigues AD, Baillie TA, Rushmore TH, Shou M.

J Pharmacol Exp Ther. 1999 Nov;291(2):749-59.

7.

A novel cis-acting element in a liver cytochrome P450 3A gene confers synergistic induction by glucocorticoids plus antiglucocorticoids.

Quattrochi LC, Mills AS, Barwick JL, Yockey CB, Guzelian PS.

J Biol Chem. 1995 Dec 1;270(48):28917-23.

8.

Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment.

Baas BJ, Denisov IG, Sligar SG.

Arch Biochem Biophys. 2004 Oct 15;430(2):218-28.

PMID:
15369821
9.
11.

Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).

He K, Woolf TF, Hollenberg PF.

J Pharmacol Exp Ther. 1999 Feb;288(2):791-7.

12.

Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.

Gillam EM, Baba T, Kim BR, Ohmori S, Guengerich FP.

Arch Biochem Biophys. 1993 Aug 15;305(1):123-31.

PMID:
8342945
13.

Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation.

Pascussi JM, Gerbal-Chaloin S, Fabre JM, Maurel P, Vilarem MJ.

Mol Pharmacol. 2000 Dec;58(6):1441-50.

14.

Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen.

Desai PB, Nallani SC, Sane RS, Moore LB, Goodwin BJ, Buckley DJ, Buckley AR.

Drug Metab Dispos. 2002 May;30(5):608-12.

17.

The cytochrome P450 3A4 inducer metyrapone is an activator of the human pregnane X receptor.

Wright MC.

Biochem Soc Trans. 1999 Aug;27(4):387-91. No abstract available.

PMID:
10917608
18.

Interindividual differences in hepatic expression of CYP3A4: relationship to genetic polymorphism in the 5'-upstream regulatory region.

Westlind A, Löfberg L, Tindberg N, Andersson TB, Ingelman-Sundberg M.

Biochem Biophys Res Commun. 1999 May 27;259(1):201-5.

PMID:
10334940
19.

Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans.

Wilkinson GR.

J Pharmacokinet Biopharm. 1996 Oct;24(5):475-90. Review.

PMID:
9131486
20.

CYP3A4 inducible model for in vitro analysis of human drug metabolism using a bioartificial liver.

Iwahori T, Matsuura T, Maehashi H, Sugo K, Saito M, Hosokawa M, Chiba K, Masaki T, Aizaki H, Ohkawa K, Suzuki T.

Hepatology. 2003 Mar;37(3):665-73.

PMID:
12601364

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