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Items: 1 to 20 of 64

1.

DNA damage response during mouse oocyte maturation.

Mayer A, Baran V, Sakakibara Y, Brzakova A, Ferencova I, Motlik J, Kitajima TS, Schultz RM, Solc P.

Cell Cycle. 2016;15(4):546-58. doi: 10.1080/15384101.2015.1128592. Epub 2016 Jan 8.

2.

Functions of the MRE11 complex in the development and maintenance of oocytes.

Inagaki A, Roset R, Petrini JH.

Chromosoma. 2016 Mar;125(1):151-62. doi: 10.1007/s00412-015-0535-8. Epub 2015 Aug 1.

3.

High NaCl causes Mre11 to leave the nucleus, disrupting DNA damage signaling and repair.

Dmitrieva NI, Bulavin DV, Burg MB.

Am J Physiol Renal Physiol. 2003 Aug;285(2):F266-74. Epub 2003 Apr 8.

4.

The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression.

Kim JH, Grosbart M, Anand R, Wyman C, Cejka P, Petrini JH.

Cell Rep. 2017 Jan 10;18(2):496-507. doi: 10.1016/j.celrep.2016.12.035.

5.

Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation.

Kanakkanthara A, Jeganathan KB, Limzerwala JF, Baker DJ, Hamada M, Nam HJ, van Deursen WH, Hamada N, Naylor RM, Becker NA, Davies BA, van Ree JH, Mer G, Shapiro VS, Maher LJ 3rd, Katzmann DJ, van Deursen JM.

Science. 2016 Sep 30;353(6307):1549-1552.

6.

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking.

Kondo T, Kobayashi J, Saitoh T, Maruyama K, Ishii KJ, Barber GN, Komatsu K, Akira S, Kawai T.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):2969-74. doi: 10.1073/pnas.1222694110. Epub 2013 Feb 6.

7.

The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.

Yu Z, Vogel G, Coulombe Y, Dubeau D, Spehalski E, H├ębert J, Ferguson DO, Masson JY, Richard S.

Cell Res. 2012 Feb;22(2):305-20. doi: 10.1038/cr.2011.128. Epub 2011 Aug 9.

8.

The mre11 complex and the response to dysfunctional telomeres.

Attwooll CL, Akpinar M, Petrini JH.

Mol Cell Biol. 2009 Oct;29(20):5540-51. doi: 10.1128/MCB.00479-09. Epub 2009 Aug 10.

9.

Role of mammalian Mre11 in classical and alternative nonhomologous end joining.

Xie A, Kwok A, Scully R.

Nat Struct Mol Biol. 2009 Aug;16(8):814-8. doi: 10.1038/nsmb.1640. Epub 2009 Jul 26.

10.

Nuclear export of NBN is required for normal cellular responses to radiation.

Vissinga CS, Yeo TC, Warren S, Brawley JV, Phillips J, Cerosaletti K, Concannon P.

Mol Cell Biol. 2009 Feb;29(4):1000-6. doi: 10.1128/MCB.01131-08. Epub 2008 Dec 15.

12.

MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene-Induced Replication Stress.

Spehalski E, Capper KM, Smith CJ, Morgan MJ, Dinkelmann M, Buis J, Sekiguchi JM, Ferguson DO.

Cancer Res. 2017 Oct 1;77(19):5327-5338. doi: 10.1158/0008-5472.CAN-17-1355. Epub 2017 Aug 17.

PMID:
28819025
13.

Recruitment and activation of the ATM kinase in the absence of DNA-damage sensors.

Hartlerode AJ, Morgan MJ, Wu Y, Buis J, Ferguson DO.

Nat Struct Mol Biol. 2015 Sep;22(9):736-43. doi: 10.1038/nsmb.3072. Epub 2015 Aug 17.

14.

Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms.

Regal JA, Festerling TA, Buis JM, Ferguson DO.

Hum Mol Genet. 2013 Dec 20;22(25):5146-59. doi: 10.1093/hmg/ddt368. Epub 2013 Aug 2.

15.

Mre11 is expressed in mammalian mitochondria where it binds to mitochondrial DNA.

Dmitrieva NI, Malide D, Burg MB.

Am J Physiol Regul Integr Comp Physiol. 2011 Sep;301(3):R632-40. doi: 10.1152/ajpregu.00853.2010. Epub 2011 Jun 15.

16.

Multiple functions of MRN in end-joining pathways during isotype class switching.

Dinkelmann M, Spehalski E, Stoneham T, Buis J, Wu Y, Sekiguchi JM, Ferguson DO.

Nat Struct Mol Biol. 2009 Aug;16(8):808-13. doi: 10.1038/nsmb.1639. Epub 2009 Jul 26.

17.

Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.

Buis J, Wu Y, Deng Y, Leddon J, Westfield G, Eckersdorff M, Sekiguchi JM, Chang S, Ferguson DO.

Cell. 2008 Oct 3;135(1):85-96. doi: 10.1016/j.cell.2008.08.015.

18.

Cancer predisposition and hematopoietic failure in Rad50(S/S) mice.

Bender CF, Sikes ML, Sullivan R, Huye LE, Le Beau MM, Roth DB, Mirzoeva OK, Oltz EM, Petrini JH.

Genes Dev. 2002 Sep 1;16(17):2237-51.

19.

The Mre11 complex suppresses oncogene-driven breast tumorigenesis and metastasis.

Gupta GP, Vanness K, Barlas A, Manova-Todorova KO, Wen YH, Petrini JH.

Mol Cell. 2013 Nov 7;52(3):353-65. doi: 10.1016/j.molcel.2013.09.001. Epub 2013 Oct 10.

20.

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