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Items: 1 to 20 of 216

1.

Protective role of Indoleamine 2,3 dioxygenase in Respiratory Syncytial Virus associated immune response in airway epithelial cells.

Rajan D, Chinnadurai R, Keefe EO, Boyoglu-Barnum S, Todd SO, Hartert TV, Galipeau J, Anderson LJ.

Virology. 2017 Dec;512:144-150. doi: 10.1016/j.virol.2017.09.007. Epub 2017 Sep 28.

PMID:
28963880
2.

Indoleamine 2,3-dioxygenase 1 deficiency attenuates CCl4-induced fibrosis through Th17 cells down-regulation and tryptophan 2,3-dioxygenase compensation.

Zhong W, Gao L, Zhou Z, Lin H, Chen C, Huang P, Huang W, Zhou C, Huang S, Nie L, Liu Y, Chen Y, Zhou D, Lv Z.

Oncotarget. 2017 Jun 20;8(25):40486-40500. doi: 10.18632/oncotarget.17119.

3.

A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells.

Mondanelli G, Bianchi R, Pallotta MT, Orabona C, Albini E, Iacono A, Belladonna ML, Vacca C, Fallarino F, Macchiarulo A, Ugel S, Bronte V, Gevi F, Zolla L, Verhaar A, Peppelenbosch M, Mazza EMC, Bicciato S, Laouar Y, Santambrogio L, Puccetti P, Volpi C, Grohmann U.

Immunity. 2017 Feb 21;46(2):233-244. doi: 10.1016/j.immuni.2017.01.005. Epub 2017 Feb 14.

4.

Platelet-activating Factor Mediates Endotoxin Tolerance by Regulating Indoleamine 2,3-Dioxygenase-dependent Expression of the Suppressor of Cytokine Signaling 3.

Noh KT, Jung ID, Cha GS, Han MK, Park YM.

J Biol Chem. 2017 Feb 24;292(8):3290-3298. doi: 10.1074/jbc.M116.764464. Epub 2017 Jan 11.

5.

IDO1 is an Integral Mediator of Inflammatory Neovascularization.

Mondal A, Smith C, DuHadaway JB, Sutanto-Ward E, Prendergast GC, Bravo-Nuevo A, Muller AJ.

EBioMedicine. 2016 Dec;14:74-82. doi: 10.1016/j.ebiom.2016.11.013. Epub 2016 Nov 9.

6.

Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine.

Laugeray A, Launay JM, Callebert J, Mutlu O, Guillemin GJ, Belzung C, Barone PR.

PLoS One. 2016 Nov 9;11(11):e0164337. doi: 10.1371/journal.pone.0164337. eCollection 2016.

7.

Indoleamine 2,3-Dioxygenase Is Not a Pivotal Regulator Responsible for Suppressing Allergic Airway Inflammation through Adipose-Derived Stem Cells.

Cho KS, Park MK, Mun SJ, Park HY, Yu HS, Roh HJ.

PLoS One. 2016 Nov 3;11(11):e0165661. doi: 10.1371/journal.pone.0165661. eCollection 2016.

8.

Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment.

Schafer CC, Wang Y, Hough KP, Sawant A, Grant SC, Thannickal VJ, Zmijewski J, Ponnazhagan S, Deshane JS.

Oncotarget. 2016 Nov 15;7(46):75407-75424. doi: 10.18632/oncotarget.12249.

9.

IDO1 and TGF-β Mediate Protective Effects of IFN-α in Antigen-Induced Arthritis.

Chalise JP, Pallotta MT, Narendra SC, Carlsson B, Iacono A, Namale J, Boon L, Grohmann U, Magnusson M.

J Immunol. 2016 Oct 15;197(8):3142-3151. Epub 2016 Sep 19.

10.

The Deficiency of Indoleamine 2,3-Dioxygenase Aggravates the CCl4-Induced Liver Fibrosis in Mice.

Ogiso H, Ito H, Ando T, Arioka Y, Kanbe A, Ando K, Ishikawa T, Saito K, Hara A, Moriwaki H, Shimizu M, Seishima M.

PLoS One. 2016 Sep 6;11(9):e0162183. doi: 10.1371/journal.pone.0162183. eCollection 2016.

11.

Hepatic stellate cells increase the immunosuppressive function of natural Foxp3+ regulatory T cells via IDO-induced AhR activation.

Kumar S, Wang J, Thomson AW, Gandhi CR.

J Leukoc Biol. 2017 Feb;101(2):429-438. doi: 10.1189/jlb.2A0516-239R. Epub 2016 Aug 31.

12.

IDO-orchestrated crosstalk between pDCs and Tregs inhibits autoimmunity.

Lippens C, Duraes FV, Dubrot J, Brighouse D, Lacroix M, Irla M, Aubry-Lachainaye JP, Reith W, Mandl JN, Hugues S.

J Autoimmun. 2016 Dec;75:39-49. doi: 10.1016/j.jaut.2016.07.004. Epub 2016 Jul 26.

13.

Tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice.

Larkin PB, Sathyasaikumar KV, Notarangelo FM, Funakoshi H, Nakamura T, Schwarcz R, Muchowski PJ.

Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2345-2354. doi: 10.1016/j.bbagen.2016.07.002. Epub 2016 Jul 5.

14.

Deletion of TDO2, IDO-1 and IDO-2 differentially affects mouse behavior and cognitive function.

Too LK, Li KM, Suarna C, Maghzal GJ, Stocker R, McGregor IS, Hunt NH.

Behav Brain Res. 2016 Oct 1;312:102-17. doi: 10.1016/j.bbr.2016.06.018. Epub 2016 Jun 15.

PMID:
27316339
15.

Differential Transcriptome Networks between IDO1-Knockout and Wild-Type Mice in Brain Microglia and Macrophages.

Gonzalez-Pena D, Nixon SE, Southey BR, Lawson MA, McCusker RH, Hernandez AG, Dantzer R, Kelley KW, Rodriguez-Zas SL.

PLoS One. 2016 Jun 17;11(6):e0157727. doi: 10.1371/journal.pone.0157727. eCollection 2016.

16.

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase.

Huang L, Ou R, Rabelo de Souza G, Cunha TM, Lemos H, Mohamed E, Li L, Pacholczyk G, Randall J, Munn DH, Mellor AL.

PLoS Pathog. 2016 May 11;12(5):e1005615. doi: 10.1371/journal.ppat.1005615. eCollection 2016 May.

17.

Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells.

Yun TJ, Lee JS, Machmach K, Shim D, Choi J, Wi YJ, Jang HS, Jung IH, Kim K, Yoon WK, Miah MA, Li B, Chang J, Bego MG, Pham TN, Loschko J, Fritz JH, Krug AB, Lee SP, Keler T, Guimond JV, Haddad E, Cohen EA, Sirois MG, El-Hamamsy I, Colonna M, Oh GT, Choi JH, Cheong C.

Cell Metab. 2016 May 10;23(5):852-66. doi: 10.1016/j.cmet.2016.04.010. Erratum in: Cell Metab. 2016 Dec 13;24(6):886.

18.

Dendritic cells transfected with indoleamine 2,3-dioxygenase gene suppressed acute rejection of cardiac allograft.

Li C, Liu T, Zhao N, Zhu L, Wang P, Dai X.

Int Immunopharmacol. 2016 Jul;36:31-38. doi: 10.1016/j.intimp.2016.03.048. Epub 2016 Apr 20.

PMID:
27107370
19.

Blockage of indoleamine 2,3-dioxygenase regulates Japanese encephalitis via enhancement of type I/II IFN innate and adaptive T-cell responses.

Kim SB, Choi JY, Uyangaa E, Patil AM, Hossain FM, Hur J, Park SY, Lee JH, Kim K, Eo SK.

J Neuroinflammation. 2016 Apr 18;13(1):79. doi: 10.1186/s12974-016-0551-5.

20.

Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1.

Moyer BJ, Rojas IY, Kerley-Hamilton JS, Hazlett HF, Nemani KV, Trask HW, West RJ, Lupien LE, Collins AJ, Ringelberg CS, Gimi B, Kinlaw WB 3rd, Tomlinson CR.

Toxicol Appl Pharmacol. 2016 Jun 1;300:13-24. doi: 10.1016/j.taap.2016.03.011. Epub 2016 Mar 25.

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