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Items: 1 to 20 of 148


Autoantibodies against the Second Extracellular Loop of M3R Do neither Induce nor Indicate Primary Sjögren's Syndrome.

Chen Y, Zheng J, Huang Q, Deng F, Huang R, Zhao W, Yin J, Song L, Chen J, Gao X, Liu Z, Petersen F, Yu X.

PLoS One. 2016 Feb 22;11(2):e0149485. doi: 10.1371/journal.pone.0149485. eCollection 2016.


BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation.

Tóth JT, Gulyás G, Tóth DJ, Balla A, Hammond GR, Hunyady L, Balla T, Várnai P.

Biochim Biophys Acta. 2016 Mar;1861(3):177-87. doi: 10.1016/j.bbalip.2015.12.005. Epub 2015 Dec 12.


Autocrine Activation of CHRM3 Promotes Prostate Cancer Growth and Castration Resistance via CaM/CaMKK-Mediated Phosphorylation of Akt.

Wang N, Yao M, Xu J, Quan Y, Zhang K, Yang R, Gao WQ.

Clin Cancer Res. 2015 Oct 15;21(20):4676-85. doi: 10.1158/1078-0432.CCR-14-3163. Epub 2015 Jun 12.


Acetylcholine ameliorates endoplasmic reticulum stress in endothelial cells after hypoxia/reoxygenation via M3 AChR-AMPK signaling.

Bi X, He X, Xu M, Zhao M, Yu X, Lu X, Zang W.

Cell Cycle. 2015 Aug 3;14(15):2461-72. doi: 10.1080/15384101.2015.1060383. Epub 2015 Jun 11.


Activation of M3 muscarinic receptor by acetylcholine promotes non-small cell lung cancer cell proliferation and invasion via EGFR/PI3K/AKT pathway.

Xu R, Shang C, Zhao J, Han Y, Liu J, Chen K, Shi W.

Tumour Biol. 2015 Jun;36(6):4091-100. doi: 10.1007/s13277-014-2911-z. Epub 2015 May 12.


Gβ4γ1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ1 subunits in the modulation of cellular signalling.

Khan SM, Min A, Gora S, Houranieh GM, Campden R, Robitaille M, Trieu P, Pétrin D, Jacobi AM, Behlke MA, Angers S, Hébert TE.

Cell Signal. 2015 Aug;27(8):1597-608. doi: 10.1016/j.cellsig.2015.04.007. Epub 2015 Apr 23.


The molecular basis of oligomeric organization of the human M3 muscarinic acetylcholine receptor.

Liste MJ, Caltabiano G, Ward RJ, Alvarez-Curto E, Marsango S, Milligan G.

Mol Pharmacol. 2015 Jun;87(6):936-53. doi: 10.1124/mol.114.096925. Epub 2015 Mar 13.


Cigarette smoking promotes inflammation in patients with COPD by affecting the polarization and survival of Th/Tregs through up-regulation of muscarinic receptor 3 and 5 expression.

Zhang MQ, Wan Y, Jin Y, Xin JB, Zhang JC, Xiong XZ, Chen L, Chen G.

PLoS One. 2014 Nov 6;9(11):e112350. doi: 10.1371/journal.pone.0112350. eCollection 2014.


Influence of gαq on the dynamics of m3-acetylcholine receptor-g-protein-coupled receptor kinase 2 interaction.

Wolters V, Krasel C, Brockmann J, Bünemann M.

Mol Pharmacol. 2015 Jan;87(1):9-17. doi: 10.1124/mol.114.094722. Epub 2014 Oct 14.


Changes in Membrane Cholesterol Differentially Influence Preferential and Non-preferential Signaling of the M1 and M3 Muscarinic Acetylcholine Receptors.

Michal P, El-Fakahany EE, Doležal V.

Neurochem Res. 2015 Oct;40(10):2068-77. doi: 10.1007/s11064-014-1325-z. Epub 2014 May 13.


M3 muscarinic acetylcholine receptor dysfunction inhibits Rac1 activity and disrupts VE-cadherin/β-catenin and actin cytoskeleton interaction.

Jiao ZY, Wu J, Wen B, Zhao WZ, Du XL.

Biochem Cell Biol. 2014 Apr;92(2):137-44. doi: 10.1139/bcb-2013-0042. Epub 2014 Jan 8.


M3 muscarinic receptor interaction with phospholipase C β3 determines its signaling efficiency.

Kan W, Adjobo-Hermans M, Burroughs M, Faibis G, Malik S, Tall GG, Smrcka AV.

J Biol Chem. 2014 Apr 18;289(16):11206-18. doi: 10.1074/jbc.M113.538546. Epub 2014 Mar 4.


M3 mAChR-mediated IL-8 expression through PKC/NF-κB signaling pathways.

Xu ZP, Song Y, Yang K, Zhou W, Hou LN, Zhu L, Chen HZ, Cui YY.

Inflamm Res. 2014 Jun;63(6):463-73. doi: 10.1007/s00011-014-0718-4. Epub 2014 Feb 13.


CHRM2 but not CHRM1 or CHRM3 polymorphisms are associated with asthma susceptibility in Mexican patients.

Jiménez-Morales S, Jiménez-Ruíz JL, Del Río-Navarro BE, Navarro-Olivos E, Escamilla-Guerrero G, Savan R, Dean M, Orozco L.

Mol Biol Rep. 2014;41(4):2109-17. doi: 10.1007/s11033-014-3060-6. Epub 2014 Jan 16.


Overexpression of muscarinic receptor 3 promotes metastasis and predicts poor prognosis in non-small-cell lung cancer.

Lin G, Sun L, Wang R, Guo Y, Xie C.

J Thorac Oncol. 2014 Feb;9(2):170-8. doi: 10.1097/JTO.0000000000000066.


High expression of M3 muscarinic acetylcholine receptor is a novel biomarker of poor prognostic in patients with non-small cell lung cancer.

Wu J, Zhou J, Yao L, Lang Y, Liang Y, Chen L, Zhang J, Wang F, Wang Y, Chen H, Ma J.

Tumour Biol. 2013 Dec;34(6):3939-44. doi: 10.1007/s13277-013-0982-x. Epub 2013 Jul 10.


Gastric body cholinergic contractile signal transduction in M2 and M3 receptor knockout mice.

Ruggieri MR, Braverman AS.

J Recept Signal Transduct Res. 2013 Aug;33(4):249-54. doi: 10.3109/10799893.2013.802803. Epub 2013 Jun 20.


Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).

Billet A, Luo Y, Balghi H, Hanrahan JW.

J Biol Chem. 2013 Jul 26;288(30):21815-23. doi: 10.1074/jbc.M113.479360. Epub 2013 Jun 11.

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