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Items: 1 to 20 of 151

1.

SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.

Hwang G, Sun F, O'Brien M, Eppig JJ, Handel MA, Jordan PW.

Development. 2017 May 1;144(9):1648-1660. doi: 10.1242/dev.145607. Epub 2017 Mar 16.

PMID:
28302748
2.

Concerted action of the MutLβ heterodimer and Mer3 helicase regulates the global extent of meiotic gene conversion.

Duroc Y, Kumar R, Ranjha L, Adam C, Guérois R, Md Muntaz K, Marsolier-Kergoat MC, Dingli F, Laureau R, Loew D, Llorente B, Charbonnier JB, Cejka P, Borde V.

Elife. 2017 Jan 4;6. pii: e21900. doi: 10.7554/eLife.21900.

3.

Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.

Alavattam KG, Kato Y, Sin HS, Maezawa S, Kowalski IJ, Zhang F, Pang Q, Andreassen PR, Namekawa SH.

Cell Rep. 2016 Oct 18;17(4):1141-1157. doi: 10.1016/j.celrep.2016.09.073.

4.

Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein.

Finsterbusch F, Ravindranathan R, Dereli I, Stanzione M, Tränkner D, Tóth A.

PLoS Genet. 2016 Oct 19;12(10):e1006393. doi: 10.1371/journal.pgen.1006393. eCollection 2016 Oct.

5.

High Mutation Levels are Compatible with Normal Embryonic Development in Mlh1-Deficient Mice.

Fan X, Li Y, Zhang Y, Sang M, Cai J, Li Q, Ozaki T, Ono T, He D.

Radiat Res. 2016 Oct;186(4):377-384. Epub 2016 Sep 19.

PMID:
27643877
6.

High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium; Jackson Laboratory; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource Center, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bućan M, Murray SA.

Nature. 2016 Sep 22;537(7621):508-514. doi: 10.1038/nature19356. Epub 2016 Sep 14.

7.

Loss of mutL homolog-1 (MLH1) expression promotes acquisition of oncogenic and inhibitor-resistant point mutations in tyrosine kinases.

Springuel L, Losdyck E, Saussoy P, Turcq B, Mahon FX, Knoops L, Renauld JC.

Cell Mol Life Sci. 2016 Dec;73(24):4739-4748. Epub 2016 Jul 19.

PMID:
27436342
8.

The genetics of human infertility by functional interrogation of SNPs in mice.

Singh P, Schimenti JC.

Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10431-6. doi: 10.1073/pnas.1506974112. Epub 2015 Aug 3.

9.

CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination.

Marjanović M, Sánchez-Huertas C, Terré B, Gómez R, Scheel JF, Pacheco S, Knobel PA, Martínez-Marchal A, Aivio S, Palenzuela L, Wolfrum U, McKinnon PJ, Suja JA, Roig I, Costanzo V, Lüders J, Stracker TH.

Nat Commun. 2015 Jul 9;6:7676. doi: 10.1038/ncomms8676.

10.

Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium.

Elliott EN, Sheaffer KL, Schug J, Stappenbeck TS, Kaestner KH.

Development. 2015 Jun 15;142(12):2163-72. doi: 10.1242/dev.117341. Epub 2015 May 28.

11.

SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination.

Hasegawa K, Sin HS, Maezawa S, Broering TJ, Kartashov AV, Alavattam KG, Ichijima Y, Zhang F, Bacon WC, Greis KD, Andreassen PR, Barski A, Namekawa SH.

Dev Cell. 2015 Mar 9;32(5):574-88. doi: 10.1016/j.devcel.2015.01.014. Epub 2015 Feb 19.

12.

Meikin is a conserved regulator of meiosis-I-specific kinetochore function.

Kim J, Ishiguro K, Nambu A, Akiyoshi B, Yokobayashi S, Kagami A, Ishiguro T, Pendas AM, Takeda N, Sakakibara Y, Kitajima TS, Tanno Y, Sakuno T, Watanabe Y.

Nature. 2015 Jan 22;517(7535):466-71. doi: 10.1038/nature14097. Epub 2014 Dec 24.

PMID:
25533956
13.

Ionizing radiation, inflammation, and their interactions in colon carcinogenesis in Mlh1-deficient mice.

Morioka T, Miyoshi-Imamura T, Blyth BJ, Kaminishi M, Kokubo T, Nishimura M, Kito S, Tokairin Y, Tani S, Murakami-Murofushi K, Yoshimi N, Shimada Y, Kakinuma S.

Cancer Sci. 2015 Mar;106(3):217-26. doi: 10.1111/cas.12591. Epub 2015 Feb 12.

14.

Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses.

Peng M, Xie J, Ucher A, Stavnezer J, Cantor SB.

EMBO J. 2014 Aug 1;33(15):1698-712. doi: 10.15252/embj.201387530. Epub 2014 Jun 25.

15.

Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites.

Holloway JK, Sun X, Yokoo R, Villeneuve AM, Cohen PE.

J Cell Biol. 2014 Jun 9;205(5):633-41. doi: 10.1083/jcb.201401122. Epub 2014 Jun 2.

16.

A role for retrotransposon LINE-1 in fetal oocyte attrition in mice.

Malki S, van der Heijden GW, O'Donnell KA, Martin SL, Bortvin A.

Dev Cell. 2014 Jun 9;29(5):521-533. doi: 10.1016/j.devcel.2014.04.027. Epub 2014 May 29.

17.

STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis.

Fukuda T, Fukuda N, Agostinho A, Hernández-Hernández A, Kouznetsova A, Höög C.

EMBO J. 2014 Jun 2;33(11):1243-55. doi: 10.1002/embj.201387329. Epub 2014 May 5.

18.
19.

Complex relationship between mismatch repair proteins and MBD4 during immunoglobulin class switch recombination.

Grigera F, Bellacosa A, Kenter AL.

PLoS One. 2013 Oct 29;8(10):e78370. doi: 10.1371/journal.pone.0078370. eCollection 2013.

20.

Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice.

Pussila M, Sarantaus L, Dermadi Bebek D, Valo S, Reyhani N, Ollila S, Päivärinta E, Peltomäki P, Mutanen M, Nyström M.

PLoS One. 2013 Oct 8;8(10):e76865. doi: 10.1371/journal.pone.0076865. eCollection 2013.

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